To help clear up your infection completely, simeprevir must be taken together with peginterferon alfa and ribavirin, or with sofosbuvir, for the full time of treatment, even if you begin to feel better after a few days. Also, it is important to keep the amount of medicine in your body at a steady level. To help keep the amount constant, simeprevir must be used on a regular schedule.
This medicine should come with a patient information leaflet. Read and follow the information carefully. Ask your doctor if you have any questions.
Swallow the capsule whole. Do not crush, break, or chew it. Take this medicine with food.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage form (capsules):
For hepatitis C virus infection, in combination with peginterferon alfa and ribavirin, or with sofosbuvir:
Adults—150 milligrams (mg) once a day.
Children—Use and dose must be determined by your doctor.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
If you miss a dose or forget to take your medicine and it is less than 12 hours from the time your regular dose was scheduled, take the capsule as soon as you can. If you miss a dose and it is more than 12 hours from the time your regular dose was scheduled, skip the missed dose and take your next dose at the regular time. Call your doctor if you have questions about this.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.