Before Using
Drug information provided by: Merative, Micromedex®
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of quinine in children younger than 16 years of age. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of quinine in the elderly.
Breastfeeding
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
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Astemizole
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Aurothioglucose
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Bepridil
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Cisapride
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Dronedarone
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Eliglustat
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Fluconazole
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Ketoconazole
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Levoketoconazole
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Mesoridazine
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Nelfinavir
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Pimozide
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Piperaquine
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Posaconazole
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Saquinavir
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Sparfloxacin
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Terfenadine
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Thioridazine
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Ziprasidone
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Adagrasib
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Alfuzosin
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Aluminum Carbonate, Basic
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Aluminum Hydroxide
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Aluminum Phosphate
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Amiodarone
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Amisulpride
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Amitriptyline
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Amoxapine
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Amphetamine
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Anagrelide
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Apomorphine
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Aripiprazole
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Aripiprazole Lauroxil
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Arsenic Trioxide
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Artemether
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Asciminib
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Asenapine
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Atazanavir
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Avacopan
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Azithromycin
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Bedaquiline
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Benzphetamine
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Berotralstat
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Buprenorphine
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Buserelin
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Carbamazepine
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Ceritinib
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Chloroquine
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Chlorpromazine
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Ciprofloxacin
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Citalopram
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Clarithromycin
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Clofazimine
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Clomipramine
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Clothiapine
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Clozapine
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Codeine
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Crizotinib
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Cyclosporine
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Dabigatran Etexilate
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Dabrafenib
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Daridorexant
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Dasatinib
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Degarelix
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Delamanid
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Desipramine
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Deslorelin
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Deutetrabenazine
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Dexmedetomidine
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Dextroamphetamine
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Digoxin
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Dihydrocodeine
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Dihydroxyaluminum Aminoacetate
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Dihydroxyaluminum Sodium Carbonate
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Disopyramide
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Dolasetron
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Domperidone
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Donepezil
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Droperidol
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Efavirenz
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Enasidenib
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Encorafenib
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Entrectinib
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Enzalutamide
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Erythromycin
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Escitalopram
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Etrasimod
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Fexinidazole
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Fingolimod
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Fluoxetine
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Formoterol
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Foscarnet
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Fostemsavir
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Gatifloxacin
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Gemifloxacin
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Gepirone
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Givinostat
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Glasdegib
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Gonadorelin
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Goserelin
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Granisetron
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Halofantrine
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Haloperidol
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Histrelin
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Hydroxyamphetamine
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Hydroxychloroquine
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Hydroxyzine
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Ibutilide
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Iloperidone
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Imipramine
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Inotuzumab Ozogamicin
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Itraconazole
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Ivabradine
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Ivosidenib
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Lacosamide
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Lanreotide
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Lapatinib
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Lefamulin
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Lenvatinib
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Leuprolide
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Levofloxacin
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Lisdexamfetamine
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Lofexidine
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Lonafarnib
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Lumefantrine
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Macimorelin
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Magaldrate
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Magnesium Carbonate
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Magnesium Hydroxide
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Magnesium Trisilicate
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Mavacamten
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Mavorixafor
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Mefloquine
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Methadone
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Methamphetamine
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Metronidazole
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Mifepristone
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Mirtazapine
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Mitotane
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Mobocertinib
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Morphine
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Morphine Sulfate Liposome
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Moxifloxacin
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Nafarelin
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Nebivolol
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Nevirapine
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Nilotinib
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Nirogacestat
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Norfloxacin
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Nortriptyline
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Octreotide
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Ofloxacin
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Olanzapine
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Ondansetron
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Osilodrostat
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Osimertinib
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Oxaliplatin
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Oxycodone
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Ozanimod
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Pacritinib
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Palbociclib
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Paliperidone
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Pancuronium
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Panobinostat
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Paroxetine
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Pasireotide
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Pazopanib
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Phenobarbital
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Pimavanserin
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Pitolisant
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Ponesimod
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Primidone
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Procainamide
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Prochlorperazine
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Promethazine
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Propafenone
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Protriptyline
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Quetiapine
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Quinidine
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Quizartinib
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Ranolazine
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Relugolix
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Repotrectinib
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Ribociclib
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Rifampin
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Rilpivirine
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Ritonavir
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Selpercatinib
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Sertraline
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Sevoflurane
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Siponimod
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Sodium Phosphate
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Sodium Phosphate, Dibasic
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Sodium Phosphate, Monobasic
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Solifenacin
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Sorafenib
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Sotalol
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Sotorasib
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Succinylcholine
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Sulpiride
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Sunitinib
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Tacrolimus
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Tamoxifen
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Taurursodiol
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Telavancin
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Telithromycin
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Tenofovir Alafenamide
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Tetrabenazine
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Tocilizumab
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Toremifene
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Tovorafenib
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Tramadol
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Trazodone
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Triclabendazole
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Trifluoperazine
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Trimipramine
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Triptorelin
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Troleandomycin
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Tubocurarine
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Tucatinib
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Vandetanib
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Vardenafil
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Vemurafenib
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Venlafaxine
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Vilanterol
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Vinflunine
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Voclosporin
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Vonoprazan
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Voriconazole
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Zuclopenthixol
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Atorvastatin
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Fosphenytoin
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Phenytoin
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Rifapentine
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Tetracycline
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
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Atrial fibrillation or flutter (abnormal heart rhythms) or
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Bradycardia (slow heartbeat) or
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Heart disease (eg, myocardial ischemia) or
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Hypokalemia (low potassium in the blood), uncorrected or
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Sick sinus syndrome (type of abnormal heart rhythm)—Use with caution. May cause side effects to become worse.
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Blackwater fever (blood disorder) or
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Hemolytic uremic syndrome (blood disorder causing serious kidney problems) or
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Idiopathic thrombocytopenia purpura (bleeding disorder) or
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Thrombocytopenia (low number of platelets) or
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Thrombotic thrombocytopenic purpura (blood disorder)—Should not be used in patients who have had these serious side effects to quinine.
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Heart rhythm problems (eg, prolonged QT interval) or
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Liver disease, severe or
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Myasthenia gravis (severe muscle weakness) or
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Optic neuritis (swelling of a nerve in the eye)—Should not be used in patients with these conditions.
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Glucose-6-phosphate dehydrogenase (G6PD) deficiency (blood disorder) or
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Hypoglycemia (low blood sugar)—Use with caution. May make this condition worse.
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Kidney disease, severe or
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Liver disease, mild to moderate—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Portions of this document last updated: Aug. 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.