Before Using
Drug information provided by: Merative, Micromedex®
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Use of progesterone is not indicated in children. Safety and efficacy have not been established.
Geriatric
Although appropriate studies on the relationship of age to the effects of progesterone have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have breast cancer, stroke, or dementia, which may require caution in patients receiving progesterone.
Breastfeeding
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Abametapir
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Avacopan
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Carbamazepine
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Clarithromycin
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Conivaptan
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Eslicarbazepine Acetate
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Fedratinib
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Fexinidazole
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Fosnetupitant
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Itraconazole
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Lonafarnib
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Mavacamten
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Netupitant
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Omaveloxolone
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Phenobarbital
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Primidone
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
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Abnormal or unusual vaginal bleeding or
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Allergy to peanuts or peanut oil or
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Blood clots (e.g., deep vein thrombosis, pulmonary embolism), active or history of or
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Breast cancer, known, suspected, or a history of or
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Heart attack, active or history of or
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Liver disease or
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Stroke, active or history of—Should not be used in patients with these conditions.
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Asthma or
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Diabetes or
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Edema (fluid retention or body swelling) or
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Endometriosis or
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Epilepsy (seizures) or
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Heart disease or
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Hypercalcemia (high calcium in the blood) or
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Hypercholesterolemia (high cholesterol in the blood) or
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Hypertension (high blood pressure) or
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Kidney disease or
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Migraine headache or
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Systemic lupus erythematosus (SLE) or
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Thyroid problems—Use with caution. May make these conditions worse.
Portions of this document last updated: Aug. 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.