Drug information provided by: IBM Micromedex
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Use of progesterone is not indicated in children. Safety and efficacy have not been established.
Although appropriate studies on the relationship of age to the effects of progesterone have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have breast cancer, stroke, or dementia, which may require caution in patients receiving progesterone.
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Abnormal or unusual vaginal bleeding or
Allergy to peanuts or peanut oil or
Blood clots (e.g., deep vein thrombosis, pulmonary embolism), active or history of or
Breast cancer, known, suspected, or a history of or
Heart attack, active or history of or
Liver disease or
Stroke, active or history of—Should not be used in patients with these conditions.
Edema (fluid retention or body swelling) or
Epilepsy (seizures) or
Heart disease or
Hypercalcemia (high calcium in the blood) or
Hypercholesterolemia (high cholesterol in the blood) or
Hypertension (high blood pressure) or
Kidney disease or
Migraine headache or
Systemic lupus erythematosus (SLE) or
Thyroid problems—Use with caution. May make these conditions worse.
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