Drug information provided by: IBM Micromedex
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
No information is available on the relationship of age to the effects of primaquine in pediatric patients.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of primaquine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Bradycardia (slow heartbeat) or
Heart disease or
Heart rhythm problems, or history of or
Hypokalemia (low potassium in the blood), uncorrected or
Hypomagnesemia (low magnesium in the blood), uncorrected—Use with caution. May prolong the QT interval.
Favism, family or personal history of or
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, mild to moderate or
Hemolytic anemia, personal or family history of or
Nicotinamide adenine dinucleotide (NADH) methemoglobin reductase deficiency—May make these conditions worse. May cause hemolytic anemia in patients with these conditions.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, severe or
Rheumatoid arthritis—Should not be used in patients with these conditions.