Proper Use

Drug information provided by: IBM Micromedex

Your doctor may have special instructions for you, depending on the schedule of your colonoscopy you are going to have. If you have not received such instructions, or if you do not understand them, check with your doctor in advance.

Take this medicine exactly as directed by your doctor. Otherwise, the test you are going to have may not work as well and may have to be done again.

This medicine comes with a Medication Guide and patient instructions. You must read, understand, and follow these instructions carefully. Ask your doctor if you have any questions.

It is best if you do not eat any solid food before taking this medicine and until after your colonoscopy.

You may drink clear liquids (eg, water, clear fruit juices (without pulp), strained limeade or lemonade, coffee or tea, broth, soda, gelatin, popsicles) before, during, and up until 2 hours before the time of your colonoscopy. Do not eat or drink alcohol, milk, anything colored red or purple or containing pulp. However, check first with your doctor.

You may have clear soup or plain yogurt for dinner on the evening that you start taking MoviPrep®. Dinner should be at least 1 hour before you take MoviPrep®.

To prepare the medicine:

  • The powder must be mixed with water before it is used. Add lukewarm water to the fill mark on the bottle. Do not add any extra flavorings or starch-based thickeners to the solution.
  • Shake well until all the ingredients are dissolved.
  • After you mix the solution, you must use it within 24 hours. You may refrigerate the solution before drinking.
  • You will need to drink 8 ounces (240 milliliters) of the mixed medicine about every 15 minutes until it is gone.
  • About 1 hour after you drink the first glass of liquid, you should have your first loose stool or mild diarrhea. This is how the medicine cleans out your bowels. You may have bloating or an upset stomach before the loose stools start.
  • If you cannot swallow the liquid, tell your doctor right away.

You will need to consume 2 liters (about 64 ounces) of the oral solution and one additional liter (about 32 ounces) of clear liquid before the test. You may do one of the following ways:

  • Split-dose (2-day regimen) method: The night before the test, drink the first liter of oral solution over 1 hour and then drink 0.5 liters (about 16 ounces) of clear liquid. Then, on the morning of the test, drink the second liter of the oral solution over 1 hour and then drink another 0.5 liters of clear liquid at least 2 hours before the test.
  • Evening-only (1-day regimen) method: The night (around 6 pm) before the test, drink the first liter of the oral solution over 1 hour. After about 1.5 hours, drink the second liter of the oral solution over one hour. Drink an additional liter of clear liquid the night before the test.
  • Do not eat or drink anything 2 hours before your colonoscopy, unless your doctor provides you with different instructions.

Do not take any medicine by mouth within 1 hour before using this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (powder for oral solution):
    • For cleansing the colon:
      • Adults—Your doctor will prescribe your dosing regimen to be taken the day or night before your colonoscopy. The dose is usually 8 ounces (240 milliliters) every 15 minutes.
        • Two-day split dosing regimen: Take the first dose between 10 to 12 hours before the second dose. The second dose must be taken at least 3 ½ hours before your colonoscopy.
        • One-day evening only dosing regimen: Take the first dose 3 1/2 hours before bedtime the evening before the colonoscopy. Take the second dose 1 1/2 hours after starting Dose 1.
      • Children—Use and dose must be determined by your doctor.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep the mixed solution in the refrigerator and use it within 24 hours.

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