Drug information provided by: Micromedex
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Infants up to 1 year of age—Safety and efficacy have not been established.
Children 1 year of age and older—This medicine has been studied in children 1 year of age and older and has not been shown to cause different side effects or problems than it does in adults. In fact, the side effects of this medicine seem to be less severe in children than in adults.
There is no specific information comparing the use of pegaspargase in the elderly with use in other age groups. Safety and efficacy of pegaspargase in the elderly have not been established.
Information about this pegaspargase-intramuscular-route-intravenous-route
||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Anticoagulant therapy (treatment with blood thinners) or
Bleeding problems—The chance of bleeding may be increased
Chickenpox (including recent exposure) or
Herpes zoster (shingles)—Risk of severe disease affecting other parts of the body
Type 2 diabetes mellitus—The chance of side effects may be increased
Infection—Pegaspargase can decrease your body's ability to fight infection
Liver disease—Effects of pegaspargase may be increased because of slower removal of this medicine from the body
Pancreatitis—The chance of side effects may be increased