Drug information provided by: IBM Micromedex
Medicines used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
This medicine comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.
Palbociclib is given together with letrozole or fulvestrant. It is important that you take each medicine at the right time. Follow your doctor's instructions on when to take these medicines.
Your doctor may also give you other medicines (eg, luteinizing hormone-releasing hormone agonists) in combination with palbociclib plus letrozole or fulvestrant if you are a pre/perimenopausal woman or a man.
Swallow the capsule or tablet whole. Do not open, crush, break, or chew it.
Take the oral capsules with food. Take the oral tablets with or without food.
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage forms (capsules or tablets):
For metastatic breast cancer with letrozole or fulvestrant:
Adults—125 milligrams (mg) once a day for 21 days, followed by 7 days without medicine. Your doctor may adjust your dose as needed and tolerated.
Children—Use and dose must be determined by your doctor.
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
If you miss a dose or vomit after you take this medicine, do not take another dose on the same day. Wait until your next dose and take it when you normally would.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.