Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of paclitaxel injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of paclitaxel injection in the elderly. However, elderly patients are more likely to have unwanted side effects (e.g., heart disease, bone marrow problems, and nerve problems), which may require caution in patients receiving paclitaxel injection.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Measles Virus Vaccine, Live
  • Mumps Virus Vaccine, Live
  • Rotavirus Vaccine, Live
  • Rubella Virus Vaccine, Live
  • Varicella Virus Vaccine, Live
  • Zoster Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abametapir
  • Abiraterone Acetate
  • Abiraterone Acetate, Micronized
  • Adenovirus Vaccine Type 4, Live
  • Adenovirus Vaccine Type 7, Live
  • Amiodarone
  • Aprepitant
  • Asciminib
  • Atazanavir
  • Avacopan
  • Bacillus of Calmette and Guerin Vaccine, Live
  • Belumosudil
  • Berotralstat
  • Bexarotene
  • Candesartan
  • Carbamazepine
  • Ceftobiprole Medocaril
  • Ceritinib
  • Cholera Vaccine, Live
  • Cisplatin
  • Clopidogrel
  • Conivaptan
  • Crizotinib
  • Dabrafenib
  • Daridorexant
  • Darolutamide
  • Dengue Tetravalent Vaccine, Live
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Ebola Zaire Vaccine, Live
  • Elexacaftor
  • Eltrombopag
  • Enasidenib
  • Enzalutamide
  • Ethinyl Estradiol
  • Fedratinib
  • Fexinidazole
  • Fluconazole
  • Fosaprepitant
  • Fosnetupitant
  • Fosphenytoin
  • Idarubicin
  • Infliximab
  • Influenza Virus Vaccine, Live
  • Itraconazole
  • Ketoconazole
  • Lanreotide
  • Lazertinib
  • Leflunomide
  • Lonafarnib
  • Mavacamten
  • Mavorixafor
  • Mitotane
  • Mobocertinib
  • Netupitant
  • Nilotinib
  • Nirogacestat
  • Octreotide
  • Omaveloxolone
  • Oxcarbazepine
  • Palbociclib
  • Pazopanib
  • Phenobarbital
  • Phenytoin
  • Pirtobrutinib
  • Pixantrone
  • Poliovirus Vaccine, Live
  • Repotrectinib
  • Resmetirom
  • Ribociclib
  • Selpercatinib
  • Smallpox Monkeypox Vaccine, Live Non-Replicating
  • Smallpox Vaccine
  • Sotorasib
  • St John's Wort
  • Taurursodiol
  • Tazemetostat
  • Teriflunomide
  • Testosterone
  • Tocilizumab
  • Tovorafenib
  • Tretinoin
  • Tucatinib
  • Typhoid Vaccine, Live
  • Valspodar
  • Voclosporin
  • Vonoprazan
  • Vorasidenib
  • Yellow Fever Vaccine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Dalfopristin
  • Lapatinib
  • Quinupristin

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bradycardia (slow heart rate) or
  • Heart rhythm problems or
  • Hypertension (high blood pressure) or
  • Hypotension (low blood pressure) or
  • Peripheral neuropathy (pain, numbness, or tingling of hands, arms, legs, or feet)—Use with caution. May make these conditions worse.
  • Infection—May decrease your body's ability to fight an infection.
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
  • Neutropenia, severe (very low white blood cells)—Should not be used in patients with this condition.

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