Ofloxacin (Oral Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

1. Abdominal or stomach pain
2. anxiety
3. black, tarry stools
4. bleeding gums
5. blood in the urine or stools
6. blurred vision
7. body aches or pain
8. chest pain
9. chills
10. cloudy urine
11. cold sweats
12. coma
13. confusion
14. congestion
15. cool, pale skin
16. cough
17. depression
18. diarrhea
19. dry mouth
20. dryness or soreness of the throat
21. eye pain
22. fast heartbeat
23. fever
24. flushed, dry skin
25. fruit-like breath odor
26. general feeling of illness
27. headache
28. hoarseness
29. increased hunger
30. increased thirst
31. increased urination
32. lower back or side pain
33. nausea
34. nightmares
35. painful or difficult urination
36. pale skin
37. pinpoint red spots on the skin
38. pus in the urine
39. runny nose
40. seizures
41. shakiness
42. slurred speech
43. sore throat
44. sores, ulcers, or white spots on the lips or in the mouth
45. sweating
46. swollen glands
47. tender, swollen glands in the neck
48. trouble with swallowing
49. troubled breathing with exertion
50. unexplained weight loss
51. unusual bleeding or bruising
52. unusual tiredness or weakness
53. voice changes
54. vomiting

Rare

1. Burning while urinating
2. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
3. change in color vision
4. continuing ringing or buzzing or other unexplained noise in the ears
5. convulsions
6. decrease in frequency of urination
7. decrease in urine volume
8. decreased hearing or any change in hearing
9. difficult or painful urination
10. difficulty in passing urine (dribbling)
11. difficulty seeing at night
12. difficulty with moving
13. discouragement
14. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
15. false or unusual sense of well-being
16. fast, irregular, pounding, or racing heartbeat or pulse
17. feeling of constant movement of self or surroundings
18. feeling of warmth or heat
19. feeling sad or empty
20. flushing or redness of the skin, especially on the face and neck
21. hearing loss
22. hives or welts, itching, or skin rash
23. increased need to urinate
24. increased sensitivity of the eyes to sunlight
25. increased sweating
26. irritability
27. joint pain
28. lack of appetite
29. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
30. loss of bladder control
31. loss of interest or pleasure
32. muscle aching or cramping
33. muscle pains or stiffness
34. muscle spasm or jerking of all extremities
35. no blood pressure or pulse
36. no breathing
37. passing urine more often
38. pounding in the ears
39. redness, soreness, or itching skin
40. seeing, hearing, or feeling things that are not there
41. sensation of spinning
42. shakiness in the legs, arms, hands, or feet
43. slow or fast heartbeat
44. sores, welting, or blisters
45. stopping of the heart
46. sudden loss of consciousness
47. swelling
48. swollen joints
49. trembling or shaking of the hands or feet
50. trouble concentrating
51. trouble performing routine tasks
52. trouble sleeping
53. unconsciousness

Incidence not known

1. Abdominal or stomach tenderness
2. actions that are out of control
3. back, leg, or stomach pains
4. blistering, peeling, or loosening of the skin
5. bloating
6. blue lips and fingernails
7. burning, dry, or itching eyes
8. changes in behavior
9. confusion about identity, place, and time
10. coughing that sometimes produces a pink frothy sputum
11. coughing up blood
12. cracks in the skin
13. crying
14. dark-colored urine
15. darkening of the skin
16. delusions of persecution, mistrust, suspiciousness, and/or combativeness
17. depersonalization
18. diarrhea, watery and severe, which may also be bloody
19. difficulty with breathing, chewing, speaking, or swallowing
20. discharge or excessive tearing
21. double vision
22. drooling
23. drooping eyelids
24. dysphoria
25. euphoria
26. feeling of discomfort
27. general body swelling
28. heartburn
29. high fever
30. hyperventilation
31. increased blood pressure
32. increased menstrual flow or vaginal bleeding
33. increased sensitivity of the skin to sunlight
34. increased sweating
35. indigestion
36. inflammation of the joints
37. irregular heartbeats
38. irregular or slow heart rate
39. itching of the vagina or outside the genitals
40. loss of ability to use or understand speech or language
41. loss of appetite
42. loss of balance control
43. loss of heat from the body
44. mental depression
45. mood or mental changes
46. muscle weakness
47. noisy breathing
48. nosebleeds
49. numbness of the hands
50. pain during sexual intercourse
51. pain in the ankles or knees
52. pain, inflammation, or swelling in the calves, shoulders, or hands
53. painful, red lumps under the skin, mostly on the legs
54. paralysis
55. prolonged bleeding from cuts
56. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
57. quick to react or overreact emotionally
58. rapidly changing moods
59. red or black, tarry stools
60. red or dark brown urine
61. red skin lesions, often with a purple center
62. red, irritated eyes
63. red, swollen skin
64. redness or other discoloration of the skin
65. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
66. restlessness
67. scaly skin
68. severe abdominal or stomach pain, cramping, or burning
69. severe sunburn
70. severe tiredness
71. shaking
72. shuffling walk
73. stiffness of the limbs
74. stomach pain, continuing
75. swelling of the face, fingers, or lower legs
76. swollen lymph glands
77. talking, feeling, and acting with excitement
78. thick, white, curd-like vaginal discharge without odor or with mild odor
79. thoughts of killing oneself
80. twisting movements of the body
81. uncontrolled eye movements
82. uncontrolled movements, especially of the face, neck, and back
83. unexplained bleeding or bruising
84. unpleasant breath odor
85. unsteadiness or awkwardness
86. unusual behavior, such as disorientation to time or place, failure to recognize people, hyperactivity, or restlessness, especially in children using 2% cyclopentolate
87. unusual weight loss
88. upper right abdominal or stomach pain
89. vomiting of blood or material that looks like coffee grounds
90. weakness in the arms, hands, legs, or feet
91. weight gain
92. yellowing of the eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

1. Change in taste
2. excess air or gas in the stomach or intestines
3. full feeling
4. loss of taste
5. passing gas
6. runny nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: Sept. 01, 2024

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