Proper Use

Drug information provided by: Micromedex

Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine should come with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

You should stop smoking completely before you start using this medicine. Do not use any tobacco products during therapy. If you continue to smoke with the nasal spray, you may have serious unwanted effects from nicotine.

It is also important to use a stop-smoking program that may include education, counseling, and psychological support. This may make it easier for you to stop smoking.

This medicine should only be used in the nose. Do not get it on your skin, or in the mouth, eyes, or ears. If the spray gets on these areas, rinse the affected area immediately and only with water.

To use:

  • Prime the spray before using it the first time.
  • Hold a tissue or paper towel over the tip. Pump the bottle 6 to 8 times until medicine sprays out.
  • If you do not use the medicine for 24 hours or longer, prime the spray again by pumping 1 or 2 times.
  • Tilt your head back slightly. Breathe through your mouth. Spray once in each nostril. Do not sniff, swallow, or inhale the spray.
  • If your nose runs after using the spray, sniff gently. You can blow your nose after 2 or 3 minutes.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For the nasal dosage form (spray):
    • To help you stop smoking:
      • Adults—At first, 1 spray in each nostril (1 milligram (mg)). The dose may be repeated 1 to 4 times during the same hour if needed. Your doctor may adjust the dose based on the number of cigarettes you smoke per day or based on how well you tolerate the medicine. However, the total dose is usually not more than 40 mg per day (40 sprays in each nostril). Your dose will be gradually reduced before stopping treatment completely.
      • Children—Use is not recommended.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

When the bottle is empty, replace the cap and throw it away. Make sure it is out of the reach of children and pets.

If the spray bottle breaks or medicine leaks out of the bottle, wear rubber gloves to wipe up the spill. Wash the area completely using a paper towel. Nicotine can be absorbed through your skin and may cause serious unwanted effects.