Proper Use

Drug information provided by: IBM Micromedex

Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Take this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine should come with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the capsule whole. Do not crush, break, chew, or open it. Take this medicine with food.

You may also receive medicines to help prevent nausea and vomiting.

If you missed a dose or vomit after taking your medicine, do not take an extra dose. Take your next dose at your scheduled dose.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For treatment of acute myeloid leukemia:
      • Adults—50 milligrams (mg) two times a day on Days 8 to 21 of each cycle of induction with cytarabine and daunorubicin, and on Days 8 to 21 of each cycle of consolidation with high-dose cytarabine.
      • Children—Use and dose must be determined by your doctor.
    • For treatment of ASM, SM-AHN, and MCL:
      • Adults—100 milligrams (mg) two times a day (about every 12 hours apart).
      • Children—Use and dose must be determined by your doctor.

Missed Dose

This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the medicine in the original package to protect from moisture.