Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of lithium extended-release tablets in children younger than 12 years of age or lithium capsules, solution, and tablets in children younger than 7 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies on the relationship of age to the effects of lithium have not been performed in the geriatric population. However, elderly patients are more likely to have age-related heart, kidney, or liver problems, which may require caution and an adjustment in the dose for patients receiving lithium.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aceclofenac
  • Acemetacin
  • Acetazolamide
  • Acetophenazine
  • Alacepril
  • Alclofenac
  • Alfentanil
  • Almotriptan
  • Amifampridine
  • Amineptine
  • Amitriptyline
  • Amitriptylinoxide
  • Amoxapine
  • Amphetamine
  • Amtolmetin Guacil
  • Anileridine
  • Aspirin
  • Azilsartan Medoxomil
  • Azosemide
  • Bemetizide
  • Benazepril
  • Bendroflumethiazide
  • Benzhydrocodone
  • Benzphetamine
  • Benzthiazide
  • Bexagliflozin
  • Bromfenac
  • Bromperidol
  • Brompheniramine
  • Bufexamac
  • Bumetanide
  • Buprenorphine
  • Bupropion
  • Buspirone
  • Butorphanol
  • Canagliflozin
  • Candesartan Cilexetil
  • Canrenoate
  • Captopril
  • Carprofen
  • Celecoxib
  • Chlorothiazide
  • Chlorpheniramine
  • Chlorpromazine
  • Chlorprothixene
  • Chlorthalidone
  • Choline Salicylate
  • Cilazapril
  • Citalopram
  • Clomipramine
  • Clonixin
  • Clozapine
  • Cocaine
  • Codeine
  • Cyclobenzaprine
  • Dapagliflozin
  • Desipramine
  • Desvenlafaxine
  • Dexibuprofen
  • Dexketoprofen
  • Dextroamphetamine
  • Dextromethorphan
  • Diazoxide
  • Dibenzepin
  • Diclofenac
  • Difenoxin
  • Diflunisal
  • Dihydrocodeine
  • Diphenoxylate
  • Dipyrone
  • Dolasetron
  • Domperidone
  • Donepezil
  • Doxepin
  • Droperidol
  • Droxicam
  • Duloxetine
  • Eletriptan
  • Empagliflozin
  • Enalapril
  • Enalaprilat
  • Eprosartan
  • Ertugliflozin
  • Escitalopram
  • Ethacrynic Acid
  • Ethopropazine
  • Ethylmorphine
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenbufen
  • Fenfluramine
  • Fenoprofen
  • Fentanyl
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Fluoxetine
  • Flupenthixol
  • Fluphenazine
  • Flurbiprofen
  • Fluvoxamine
  • Fosinopril
  • Frovatriptan
  • Furazolidone
  • Furosemide
  • Gepirone
  • Granisetron
  • Haloperidol
  • Hydrochlorothiazide
  • Hydrocodone
  • Hydroflumethiazide
  • Hydromorphone
  • Hydroxyamphetamine
  • Hydroxytryptophan
  • Ibuprofen
  • Imipramine
  • Indapamide
  • Indomethacin
  • Iproniazid
  • Irbesartan
  • Isocarboxazid
  • Ketobemidone
  • Ketoprofen
  • Ketorolac
  • Lasmiditan
  • Levomilnacipran
  • Levorphanol
  • Linezolid
  • Lisdexamfetamine
  • Lisinopril
  • Lofepramine
  • Lorcaserin
  • Lornoxicam
  • Losartan
  • Loxapine
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Melitracen
  • Meloxicam
  • Melperone
  • Meperidine
  • Mesoridazine
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methotrimeprazine
  • Methyclothiazide
  • Methylene Blue
  • Metolazone
  • Metronidazole
  • Milnacipran
  • Mirtazapine
  • Moclobemide
  • Moexipril
  • Molindone
  • Morniflumate
  • Morphine
  • Morphine Sulfate Liposome
  • Nabumetone
  • Nalbuphine
  • Naproxen
  • Naratriptan
  • Nefazodone
  • Nepafenac
  • Nialamide
  • Nicomorphine
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Nortriptyline
  • Olanzapine
  • Oliceridine
  • Olmesartan Medoxomil
  • Ondansetron
  • Opipramol
  • Opium
  • Opium Alkaloids
  • Oxaprozin
  • Oxycodone
  • Oxymorphone
  • Oxyphenbutazone
  • Palonosetron
  • Papaveretum
  • Parecoxib
  • Paregoric
  • Paroxetine
  • Penfluridol
  • Pentazocine
  • Periciazine
  • Perindopril
  • Perphenazine
  • Phenelzine
  • Phenylbutazone
  • Piketoprofen
  • Pimozide
  • Pipamperone
  • Pipotiazine
  • Piretanide
  • Piritramide
  • Piroxicam
  • Polythiazide
  • Pranoprofen
  • Procarbazine
  • Prochlorperazine
  • Proglumetacin
  • Promazine
  • Promethazine
  • Propyphenazone
  • Proquazone
  • Protriptyline
  • Quinapril
  • Ramipril
  • Rasagiline
  • Remifentanil
  • Remoxipride
  • Risperidone
  • Rizatriptan
  • Rofecoxib
  • Safinamide
  • Salicylic Acid
  • Salsalate
  • Selegiline
  • Sertindole
  • Sertraline
  • Sibutramine
  • Sodium Salicylate
  • Sotagliflozin
  • Spirapril
  • Spironolactone
  • St John's Wort
  • Sufentanil
  • Sulindac
  • Sulpiride
  • Sumatriptan
  • Suprofen
  • Tapentadol
  • Telmisartan
  • Tenoxicam
  • Thiopropazate
  • Thioproperazine
  • Thioridazine
  • Thiothixene
  • Tianeptine
  • Tiapride
  • Tiaprofenic Acid
  • Tilidine
  • Tolfenamic Acid
  • Tolmetin
  • Topiramate
  • Torsemide
  • Tramadol
  • Trandolapril
  • Tranylcypromine
  • Trichlormethiazide
  • Trifluoperazine
  • Triflupromazine
  • Trimeprazine
  • Trimipramine
  • Tryptophan
  • Valdecoxib
  • Valsartan
  • Venlafaxine
  • Vilazodone
  • Vortioxetine
  • Xipamide
  • Ziprasidone
  • Zofenopril
  • Zolmitriptan
  • Zotepine
  • Zuclopenthixol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Calcitonin
  • Carbamazepine
  • Cisplatin
  • Diltiazem
  • Lactulose
  • Mazindol
  • Phenytoin
  • Succinylcholine
  • Verapamil
  • Yohimbine

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Caffeine

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Brugada syndrome (heart disorder), or family history of or
  • Decreased urination or
  • Diarrhea, prolonged or
  • Infection, severe with fever or
  • Kidney disease or
  • Sweating, prolonged or
  • Vomiting, prolonged—May increase risk for serious side effects.
  • Dehydration, severe or
  • Heart or blood vessel disease or
  • Hyponatremia (low sodium in the blood) or
  • Kidney disease, severe or
  • Muscle weakness, severe or
  • Weakened physical condition—Should not be used in patients with these conditions.
  • Encephalopathic syndrome (brain disease) or
  • Goiter or other thyroid problems or
  • Nervous system problems—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

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Portions of this document last updated: May 01, 2024

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