Precautions

It is very important that your doctor check you and your child's progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

Receiving this medicine while you are pregnant can harm your unborn baby. It may also cause birth defects if the father is receiving it when his sexual partner becomes pregnant. Female patients should use effective birth control during treatment with this medicine and for 7 months after the last dose. Male patients who have female partners should use effective birth control during treatment with this medicine and for 4 months after the last dose. If you think you have become pregnant while receiving this medicine, tell your doctor right away.

You or your child will be exposed to radiation when this medicine is given. Talk with your doctor if you have concerns about this.

This medicine is passed mainly in the urine where radioactivity is present. Follow these guidelines after receiving iobenguane I 131 injection, to help reduce the chance of contaminating other persons or the environment with radiation:

  • Use a normal toilet, if available, instead of a urinal.
  • To prevent contamination of your home environment, flush the toilet several times after using.
  • Wipe any spilled urine with a tissue and flush it away.
  • Wash your hands after using or cleaning the toilet.
  • Wash your clothes and bed linens right away if they become soiled with your urine or blood. Wash them separately from other clothes.
  • If you cut yourself, was h away any spilled blood.

This medicine may lower the number of some types of blood cells in your body. Because of this, you or your child may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.

Check with your doctor right away if you or your child have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, troubled breathing, unusual tiredness or weakness, vomiting, or weight gain. These could be symptoms of a serious kidney problem.

This medicine may cause swelling of the lungs (pneumonitis), which can be life-threatening and requires immediate medical attention. Check with your doctor right away if you or your child have new or worsening cough, fever, or trouble breathing.

If you plan to have children, talk with your doctor before receiving this medicine. Some men and women receiving this medicine have become infertile (unable to have children).

Do not take other medicines until at least 7 days after each dose of iobenguane I 131 injection or unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, ma huang, St. John’s Wort, yohimbine) or vitamin supplements.