Before Using

Drug information provided by: Merative, Micromedex®

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of glycopyrrolate injection in children to treat peptic ulcer. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of glycopyrrolate injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Potassium Chloride
  • Potassium Citrate

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aclidinium
  • Amantadine
  • Amifampridine
  • Amitriptyline
  • Amoxapine
  • Atropine
  • Belladonna
  • Benztropine
  • Biperiden
  • Brompheniramine
  • Buprenorphine
  • Bupropion
  • Carbinoxamine
  • Carisoprodol
  • Chlorpheniramine
  • Chlorpromazine
  • Clemastine
  • Clidinium
  • Clomipramine
  • Clozapine
  • Codeine
  • Cyclobenzaprine
  • Cyclopentolate
  • Cyproheptadine
  • Darifenacin
  • Desipramine
  • Dicyclomine
  • Dimenhydrinate
  • Diphenhydramine
  • Donepezil
  • Doxepin
  • Fentanyl
  • Fesoterodine
  • Flavoxate
  • Fluphenazine
  • Glucagon
  • Glycopyrronium Tosylate
  • Homatropine
  • Hydroxyzine
  • Hyoscyamine
  • Imipramine
  • Ipratropium
  • LetibotulinumtoxinA-wlbg
  • Loxapine
  • Meclizine
  • Mepenzolate
  • Methacholine
  • Methadone
  • Nortriptyline
  • Olanzapine
  • Oliceridine
  • Orphenadrine
  • Oxitropium Bromide
  • Oxybutynin
  • Oxycodone
  • Paroxetine
  • Perphenazine
  • Pimozide
  • Pipenzolate Bromide
  • Pirenzepine
  • Prochlorperazine
  • Procyclidine
  • Promethazine
  • Propantheline
  • Propiverine
  • Protriptyline
  • Quetiapine
  • Revefenacin
  • Scopolamine
  • Secretin Human
  • Solifenacin
  • Stramonium
  • Sufentanil
  • Tapentadol
  • Terodiline
  • Thioridazine
  • Thiothixene
  • Tiotropium
  • Tizanidine
  • Tolterodine
  • Tramadol
  • Trifluoperazine
  • Trihexyphenidyl
  • Trimipramine
  • Tropicamide
  • Trospium
  • Umeclidinium

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Brain damage or
  • Down syndrome or
  • Spastic paralysis (persistent muscle spasms)—Use with caution in children with these conditions. May increase risk for more serious side effects.
  • Glaucoma or
  • Heart or blood vessel problem with bleeding, unstable or
  • Myasthenia gravis (severe muscle weakness) or
  • Problems passing urine (eg, bladder neck obstruction, prostatic hypertrophy) or
  • Stomach or bowel blockage (eg, achalasia, pyloroduodenal stenosis, paralytic ileus) or
  • Stomach or bowel problems (eg, bowel weakness, ulcerative colitis, toxic megacolon)—Should not be used in patients with these conditions.
  • Heart disease or
  • Heart failure or
  • Heart rhythm problems (eg, arrhythmia) or
  • Hiatal hernia or
  • Hypertension (high blood pressure) or
  • Hyperthyroidism (overactive thyroid) or
  • Kidney disease or
  • Liver disease or
  • Neuropathy (nerve disease) or
  • Surgery in your bowels (eg, colostomy, ileostomy)—Use with caution. May cause side effects to become worse.

Portions of this document last updated: May 01, 2024

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