Description and Brand Names

Drug information provided by: IBM Micromedex

Descriptions


Fosdenopterin injection is used to help reduce the risk of death caused by molybdenum cofactor deficiency (MoCD) type A.

This medicine is to be given only by or under the supervision of your doctor.

This product is available in the following dosage forms:

  • Powder for Solution

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fosdenopterin injection in the pediatric population. Safety and efficacy have been established.

Geriatric

No information is available on the relationship of age to the effects of fosdenopterin injection in geriatric patients. MoCD is usually a disease of young children.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use

A nurse or other trained health professional will give you this medicine in a medical facility. It is given through a needle placed into one of your veins. You or your child's caregiver may be trained to prepare and inject this medicine at home. Be sure that you understand how to use the medicine.

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Precautions

It is very important that your doctor check your child's progress closely while your child is receiving this medicine to make sure that the medicine is working properly.

This medicine may cause photosensitivity. Check with your doctor right away if your child has increased sensitivity of the skin to sunlight, itching, redness or other discoloration of the skin, severe sunburn, or skin rash. Use sunscreen or sunblock lotions with a sun protection factor (SPF) on a regular basis when you are outdoors. Wear protective clothing and hats and avoid sunlamps and tanning beds.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Chills
  2. cold flu-like symptoms
  3. cough or hoarseness
  4. fever
  5. increased sensitivity of the skin to sunlight
  6. itching
  7. redness or other discoloration of the skin
  8. severe sunburn
  9. skin rash

Less common

  1. Agitation
  2. body aches or pain
  3. chest pain or tightness
  4. cough
  5. diarrhea
  6. earache
  7. ear congestion
  8. headache
  9. loss of appetite
  10. loss of voice
  11. nausea
  12. pale skin
  13. rash with flat lesions or small raised lesions on the skin
  14. redness or swelling in the ear
  15. runny or stuffy nose
  16. seizures
  17. sneezing
  18. sore throat
  19. stomach pain
  20. swelling of the eye
  21. trouble breathing
  22. unusual bleeding or bruising
  23. unusual tiredness or weakness
  24. vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.