Proper Use

Drug information provided by: IBM Micromedex

A nurse or other trained health professional will give you this medicine. This medicine is given as a shot under the skin.

This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

You might be taught how to give your medicine at home. If you are using this medicine at home:

  • Wash your hands with soap and water and use a clean work area to prepare your injection.
  • Make sure you understand and carefully follow your doctor's instructions on how to give yourself an injection, including the proper use of a needle and syringe.
  • Check the solution in the vial. It should be clear and colorless. If it is cloudy, discolored, or contains large particles, do not use it.
  • Do not inject more or less of the medicine than your doctor ordered.
  • You will be shown the body areas (eg, stomach, upper arm, or upper leg) where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will prevent skin problems.
  • Use a new needle and syringe each time you inject your medicine.
  • It is very important that you keep track of each dose you inject. Your doctor or nurse will help you with this.

Tell your doctor when you use the last dose of follitropin alfa. Follitropin alfa often requires that another hormone called human chorionic gonadotropin (hCG) be given as a single dose the day after the last dose of follitropin alfa is given. Your doctor will give you this medicine or arrange for you to get this medicine at the right time.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (powder for solution):
    • For treatment of female infertility:
      • Adults—At first, 75 international units (IU) injected under the skin once a day for 14 days. Your doctor will adjust your dose up to 37.5 IU every 7 days. However, the dose is usually not more than 300 IU per day.
      • Children—Use is not recommended.
    • For use with assisted reproductive technology (ART) procedures:
      • Adults—At first, 150 international units (IU) injected under the skin once a day for not more than 10 days beginning on Day 2 or Day 3 of your menstrual cycle. Your doctor will adjust your dose to 75 to 150 IU every 3 to 5 days. However, the dose is usually not more than 450 IU per day. Some patients may start treatment at a dose of 225 IU once a day.
      • Children—Use is not recommended.
    • For treatment of male infertility
      • Adults—150 international units (IU) injected under the skin 3 times a week together with 1000 USP Units of human chorionic gonadotropin (hCG) 3 times a week. Your doctor will adjust your dose if needed. However, dose is not usually more than 300 IU 3 times a week. You may be given this medicine up to 18 months.
      • Children—Use is not recommended.

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Gonal-F®: Store the unused powder in the refrigerator or at room temperature. Protect from light. You may store the mixed medicine in the refrigerator or at room temperature. Throw away unused mixed medicine after 28 days.

Gonal-F RFF®: Store the unused powder in the refrigerator or at room temperature. Protect from light. Use this medicine right away after mixing. Throw away unused mixed medicine.

Throw away used needles and syringes in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.