Proper Use

Drug information provided by: IBM Micromedex

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor or pharmacist if you have any questions.

It is important that you take this medicine together with other medicines for HIV. Be sure to take all of the medicines your doctor ordered, and to take them at the right times. If you need help in planning the best times to take your medicine, talk with your doctor.

It is best to take etravirine following a meal.

Swallow the tablet whole with a liquid (eg, water). Do not chew it. If you or your child cannot swallow the tablet whole, you may dissolve it in a glass with a small amount of water (1 teaspoon). Stir until the water looks milky. You may also add more water, orange juice, or milk to make it easier to take. Do not use grapefruit juice, or warm or carbonated drinks. Be sure to drink or swallow the entire mixture right away. Then refill your glass with water, orange juice, or milk and drink it so that none of the medicine is left in the glass. .

Keep taking etravirine for the full time of treatment, even if you or your child begin to feel better. Do not change the amount or stop taking this medicine without checking first with your doctor. .

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. .


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For HIV infection:
      • Adults—200 milligrams (mg) (one 200 mg tablet or two 100 mg tablets) taken 2 times a day.
      • Children 2 to 17 years of age—Dose is based on body weight and must be determined by your doctor.
        • Weighing 30 kilograms (kg) or more—200 mg taken 2 times a day.
        • Weighing 25 kg to less than 30 kg—150 mg taken 2 times a day.
        • Weighing 20 kg to less than 25 kg—125 mg taken 2 times a day.
        • Weighing 10 kg to less than 20 kg—100 mg taken 2 times a day.
      • Children younger than 2 years of age and weighing less than 10 kg—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.