Precautions

Drug information provided by: Merative, Micromedex®

Your doctor will want to check your or your child's progress at regular visits, especially during the first few weeks that you take this medicine. Blood and urine tests may be needed to check for any unwanted effects.

Do not use this medicine together with carbamazepine (Tegretol®), enzalutamide (Xtandi®), mitotane (Lysodren®), oxcarbazepine (Trileptal®), phenobarbital (Luminal®), phenytoin (Dilantin®), rifampin (Rifadine®), rifapentine (Priftin®), or St John's wort. Tell your doctor if your have taken any of these medicines within the past 4 weeks before you start treatment with this medicine.

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.

This medicine may increase the risk of kidney problems (eg, acute kidney failure, Fanconi syndrome). To lower this risk, avoid other medicines that can be harmful to the kidneys including aminoglycoside antibiotics, certain other antiviral medicines, and NSAID pain medicines.

This medicine may also increase your risk of developing fractures (broken bones). Ask your doctor about this if you have any concerns.

Your immune system may get stronger when you start taking HIV medicines. Tell your doctor right away if you notice any changes in your health. Sometimes the immune system will start to fight infections that were hidden in your body, such as pneumonia, herpes, or tuberculosis. Autoimmune disorders (eg, Graves' disease, polymyositis, autoimmune hepatitis, and Guillain-Barré syndrome) may also occur.

This medicine does not decrease the risk of transmitting the HIV infection to others through sexual contact or by contaminated blood. Make sure you understand and practice safe sex, even if your partner also has HIV. Avoid sharing needles with anyone.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or non-prescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.