Proper Use

Drug information provided by: Merative, Micromedex®

Medicines used to treat cancer are very strong and can have many side effects. Before using this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine should come with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Take this medicine on an empty stomach. Do not eat for at least 2 hours before and 2 hours after using this medicine. Take it at the same time each day.

Swallow the tablet whole. Do not cut, crush, or chew it.

You may receive other medicines to help prevent nausea and vomiting.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (extended-release tablets):
    • For myelodysplastic syndromes:
      • Adults—One tablet once a day on Days 1 to 5 of each 28-day cycle for at least 4 cycles. Each tablet contains 35 milligrams (mg) of decitabine and 100 mg of cedazuridine. Your doctor may adjust your dose as needed or tolerated.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss a dose and it is within 12 hours of your usual dose, take it as soon possible and go back to your regular dosing schedule. If you miss a dose and it is more than 12 hours of your usual dose, skip the missed dose and go back to your regular dosing schedule.

If you vomit after taking a dose, do not take an additional dose. Take the next dose at the regular time.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep the medicine in its original container.

Portions of this document last updated: Feb. 01, 2024

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