Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

1. Abdominal or stomach pain or tenderness
2. back pain
3. black, tarry stools
4. blurred vision
5. chest pain
6. chills
7. clay colored stools
8. cloudy urine
9. cough
10. dark urine
11. decrease in urine output or decrease in urine-concentrating ability
12. decreased appetite
13. dizziness
14. drowsiness
15. fever
16. headache
17. headache, severe and throbbing
18. itching
19. loss of appetite
20. muscle spasms (tetany) or twitching
21. nausea and vomiting
22. nervousness
23. painful or difficult urination
24. pounding in the ears
25. shakiness in the legs, arms, hands, or feet
26. shortness of breath
27. skin rash
28. slow or fast heartbeat
29. sore throat
30. sores, ulcers, or white spots on the lips or in the mouth
31. swelling of the feet or lower legs
32. swollen glands
33. trembling or shaking of the hands or feet
34. unusual bleeding or bruising
35. unusual tiredness or weakness
36. yellow eyes or skin

Less common

1. Bleeding gums
2. blood in the urine
3. blood in the vomit
4. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
5. convulsions
6. difficulty swallowing
7. hives
8. pale skin
9. pinpoint red spots on the skin
10. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
11. severe or continuing stomach pain
12. tightness in the chest
13. troubled breathing with exertion

Rare

1. Bloating
2. chest discomfort
3. constipation
4. darkened urine
5. hoarseness
6. indigestion
7. lower back or side pain
8. night sweats
9. pain or discomfort in the arms, jaw, back, or neck
10. pains in the stomach, side, or abdomen, possibly radiating to the back
11. sweating
12. vomiting of blood or material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

1. Abdominal or stomach discomfort
2. bleeding, tender, or enlarged gums
3. blemishes on the skin
4. increased hair growth, especially on the face
5. pain or tenderness around the eyes and cheekbones
6. pimples
7. stuffy or runny nose

Less common

1. Brittle fingernails
2. burning feeling in the chest or stomach
3. burning, dry, or itching eyes
4. continuing ringing or buzzing or other unexplained noise in the ears
5. cramps
6. discharge or excessive tearing
7. feeling of warmth
8. hearing loss
9. redness of the face, neck, arms, and occasionally, upper chest
10. redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
11. swelling of the breasts or breast soreness in both females and males
12. weight loss

Rare

1. Blurred or loss of vision
2. discouragement
3. disturbed color perception
4. double vision
5. fear
6. feeling sad or empty
7. halos around lights
8. irritability
9. joint pain
10. loss of interest or pleasure
11. night blindness
12. overbright appearance of lights
13. tiredness
14. trouble concentrating
15. trouble sleeping
16. tunnel vision
17. unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
18. weakness
19. weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Portions of this document last updated: Sept. 01, 2023

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