Proper Use

Drug information provided by: IBM Micromedex

It is very important that you use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects.

This medicine comes with a patient information leaflet. Read and follow the instructions in the leaflet carefully. Ask your doctor if you have any questions.

This medicine is to be used only in the vagina. Use at bedtime unless your doctor tells you otherwise.

To use the cream:

  • Wash your hands with soap and water before and after using this medicine.
  • Remove cap from the tube and screw the nozzle end of the applicator to the tube.
  • Gently squeeze tube from the bottom to force enough amount into the barrel. Use the marked stopping points on the applicator to measure the correct dose.
  • Unscrew the applicator from the tube, and lie on the back with knees drawn up, and gently insert the applicator deeply into the vagina and press plunger downward to its original position.
  • Wash the applicator with mild soap and water. Do not use hot water.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For vaginal dosage form (cream):
    • For treatment of atrophic vaginitis and kraurosis vulvae:
      • Adults—At first, use 0.5 gram (g) into the vagina once a day. Your doctor may adjust your dose as needed. The medicine is used in cycles (using the medicine for 21 days, followed by 7 days without medicine).
      • Children—Use is not recommended.
    • For treatment of painful sexual intercourse:
      • Adults—Use 0.5 gram (g) in the vagina two times a week, or in cycles (using the medicine for 21 days, followed by 7 days without medicine).
      • Children—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.