Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

  1. Mental depression
  2. swelling of the feet and lower legs

Rare

  1. Anxiety
  2. blistering, burning, crusting, dryness, or flaking of the skin
  3. chest pain or discomfort
  4. confusion as to time, place, or person
  5. decreased urine output
  6. dilated neck veins
  7. drowsiness
  8. dry mouth
  9. fast, pounding, or irregular heartbeat or pulse
  10. fever
  11. general feeling of discomfort or illness
  12. holding false beliefs that cannot be changed by fact
  13. hyperventilation
  14. irregular breathing
  15. irritability
  16. itching, scaling, severe redness, soreness, or swelling of the skin
  17. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  18. lightheadedness, dizziness, or fainting
  19. mental depression
  20. paleness or cold feeling in the fingertips and toes
  21. pounding, slow heartbeat
  22. problems in urination or increase in the amount of urine
  23. raised red swellings on the skin, lips, tongue, or in the throat
  24. restlessness
  25. seeing or hearing things that are not there
  26. shaking
  27. shortness of breath
  28. skin rash
  29. swelling of the face, fingers, feet, or lower legs
  30. tightness in the chest
  31. tingling or pain in the fingers or toes when exposed to cold
  32. trouble with sleeping
  33. troubled breathing
  34. unusual excitement, nervousness, or restlessness
  35. unusual tiredness or weakness
  36. vivid dreams or nightmares
  37. weight gain
  38. wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Dizziness (extreme) or faintness
  2. feeling cold
  3. pinpoint pupils of the eyes
  4. unusual tiredness or weakness (extreme)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Constipation

Less common

  1. Darkening of the skin
  2. decreased sexual ability
  3. dry, itching, or burning eyes
  4. loss of appetite
  5. nausea or vomiting

Rare

  1. Blurred vision
  2. decreased interest in sexual intercourse
  3. hair loss or thinning of the hair
  4. inability to have or keep an erection
  5. leg cramps
  6. loss in sexual ability, desire, drive, or performance
  7. muscle or joint pain
  8. pale skin
  9. swelling of the breasts or breast soreness in both females and males
  10. weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.

Portions of this document last updated: Sept. 01, 2023