Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Take this medicine with meals.

To help clear up your leprosy completely, it is very important that you keep using clofazimine for the full time of treatment, even if you begin to feel better after a few months. You may have to take it every day for as long as 2 to 3 years. If you stop using this medicine too soon, your symptoms may return, worsen, or infect other people.

This medicine is taken together with other medicines (eg, other antileprosy medicines, steroids). Follow your doctor's orders on the right times to take these medicines.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take each dose at the same time every day. If you need help in planning the best time to take your medicines, check with your doctor or pharmacist.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For lepromatous leprosy (dapsone-sensitive):
      • Adults—100 milligrams (mg) in combination with two other antileprosy drugs for at least 2 years. Your doctor may give you an appropriate antileprosy drug after.
      • Children—Use and dose must be determined by your doctor.
    • For lepromatous leprosy (dapsone-resistant):
      • Adults—100 milligrams (mg) in combination with one or more other antileprosy drugs for 3 years. Your doctor may then give you 100 mg of clofazimine once a day.
      • Children—Use and dose must be determined by your doctor.
    • For lepromatous leprosy complicated by erythema nodosum leprosum:
      • Adults—100 to 200 milligrams (mg) once a day for up to 3 months, in combination with other antileprosy drugs and steroids. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.