Precautions
Drug information provided by: Merative, Micromedex®
It is very important that your doctor check your progress at regular visits. This is necessary to allow dose adjustments and to check for serious unwanted effects.
Serious skin reactions (including drug reaction with eosinophilia and systemic symptoms (DRESS) may occur during treatment with cenobamate. Tell your doctor right away if you have a fever, skin rashes or blisters, or swollen, painful, or tender lymph glands in neck, armpit, or groin while using this medicine.
Contact your doctor right away if you have any changes to your heart rhythm. You might feel dizzy or faint, or you might have a fast or uneven heartbeat that last a long time. These may be symptoms of a heart rhythm problem called QT shortening.
If you develop any unusual or strange thoughts and behavior while taking this medicine, be sure to discuss it with your doctor. Other changes might be confusion, worsening of depression, suicidal thoughts, and unusual excitement, nervousness, or irritability.
Cenobamate may cause blurred vision, double vision, or other changes in vision. It may also cause some people to become dizzy, drowsy, clumsy, or feel tired. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to see well.
Do not stop taking cenobamate without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping completely. Stopping the medicine suddenly may cause your seizures to return or to occur more often.
This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, barbiturates, medicine for seizures, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor or dentist before taking any of the above while you are taking this medicine.
Birth control pills may not work while you are using cenobamate. To keep from getting pregnant, use another form of birth control including condoms, diaphragms, or contraceptive foams or jellies.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Portions of this document last updated: April 01, 2024
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