Proper Use

Drug information provided by: IBM Micromedex

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions.

Keep taking cabotegravir for the full time of treatment, even if you begin to feel better. Do not stop taking it without checking first with your doctor.

It is important to take cabotegravir together with rilpivirine. Take all other medicines your doctor has prescribed at the right time of day. This will make your medicines work better.

You may take this medicine alone with or without food. Take this medicine with food it taking together with rilpivirine.

Take antacid containing aluminum, magnesium, or calcium 2 hours before or 4 hours after you take cabotegravir.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For short-term treatment of HIV infection:
      • To assess the tolerability of cabotegravir before receiving Cabenuva:
        • Adults—30 milligrams (mg) in combination with 25 mg of rilpivirine once a day for at least 28 days. Your last dose should be taken on the same day injections Cabenuva injections are started.
        • Children—Use and dose must be determined by your doctor.
      • For patients who will miss a planned injection of Cabenuva (up to 2 consecutive monthly injections):
        • Adults—If you miss or plan to miss a scheduled monthly injection of Cabenuva injection by more than 7 days, take 30 milligrams (mg) in combination with 25 mg of rilpivirine once a day. Your first dose should be taken at least 1 month after the last Cabenuva injection and continued until the day injection dosing is restarted.
        • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.