Proper Use

Drug information provided by: Merative, Micromedex®

This medicine is given as a shot under the skin of your thigh, stomach, or upper arm. It may be given at home to patients who do not need to be in the hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use this medicine.

It is very important that you understand the requirements of the Siliq™ REMS program, and become familiar with the Siliq™ Medication Guide and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions. Ask your pharmacist for the medication guide if you do not have one.

You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections. Do not inject into skin areas that are bruised, red, hard, tender, thick, scaly, or areas with psoriasis.

You might not use all of the medicine in each prefilled syringe. Use each prefilled syringe only one time. Do not save an open syringe. If the medicine in the syringe has changed color, or if you see particles in it, do not use it. Do not shake.

To use the prefilled syringe:

  • Wash your hands with soap and water before and after using this medicine.
  • Allow 30 minutes for the prefilled syringe to warm up to room temperature. Do not warm using heat sources (eg, hot water, microwave, or sunlight).
  • Check the liquid in the prefilled syringe. It should be clear and colorless to slightly yellow. Do not use it if it is cloudy, discolored, or has flakes or particles in it. Do not shake.
  • Pull the gray needle cap straight off and away from your body. Do not twist or bend the gray needle cap. Do not recap the needle.
  • Pinch skin firmly between your thumb and fingers. Insert the needle into your skin.
  • Push the plunger rod all the way down until it reaches the bottom. Gently lift the syringe and pull the needle our of your skin.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (prefilled syringe):
    • For plaque psoriasis:
      • Adults—210 milligrams (mg) injected under your skin as a single dose at Weeks 0, 1, and 2. This is followed by 210 mg every 2 weeks.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Keep the medicine in the original carton until you are ready to use it. You may store the prefilled syringe at room temperature for up to 14 days. Do not put it back in the refrigerator once it has reached room temperature. Throw away any unused medicine that has been stored at room temperature after 14 days. Do not freeze.

Throw away used syringes in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Portions of this document last updated: Sept. 01, 2024

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