Drug information provided by: IBM Micromedex
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Use of alendronate and cholecalciferol combination is not indicated in children.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alendronate and cholecalciferol combination in the elderly.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
Blood clotting problems or
Dental or tooth problems or
Dental procedures (eg, dental implants, tooth extraction) or
Poor oral hygiene or
Surgery (eg, dental surgery)—May increase risk for severe jaw problems.
Blood or bone marrow problems (eg, leukemia, lymphoma, sarcoidosis)—Use with caution. May cause changes in vitamin D.
Esophagus (the tube that runs from your throat to your stomach) problems (eg, achalasia, stricture) or
Hypocalcemia (low calcium in the blood) or
Inability to stand or sit upright for at least 30 minutes or
Kidney disease, severe or
Trouble with swallowing—Should not be used in patients with these conditions.
Stomach or bowel problems (eg, Barrett's esophagus, duodenitis, gastritis, heartburn, inflammation of the esophagus, or ulcers)—Use with caution. May make these conditions worse.
Vitamin D deficiency—Should be treated first before using this medicine.
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