Proper Use

Drug information provided by: IBM Micromedex

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Also, do not change the dose, switch medicines, or stop using this medicine without checking first with your doctor. When your supply of this medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of this medicine.

Abacavir, dolutegravir, and lamivudine combination contains a fixed amount of each medicine in the tablet and the tablet for suspension (oral liquid). Do not substitute these dosage forms for each other. Always check your medicine each time your prescription is filled to make sure you receive the correct dosage form.

This medicine should come with a Medication Guide and instructions for use. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Keep taking this medicine for the full time of treatment, even if you begin to feel better. It is also important to take this medicine together with other medicines for HIV. Be sure to take all of the medicines your doctor ordered, and to take them at the right times.

You may take this medicine with or without food.

Swallow the tablet whole. Do not chew, cut, or crush it.

To use the oral liquid:

  • Mix the tablet for suspension with 20 milliliters (mL) of drinking water in the supplied cup. Use drinking water only. Do not mix this medicine with any other drink or food.
  • Swirl the cup gently for 1 to 2 minutes to dissolve the tablet. The medicine will become cloudy. Swirl the cup again to make sure there are no lumps of the tablet remain.
  • Swallow the liquid within 30 minutes of mixing. If the medicine has not been taken after 30 minutes, wash away all the liquid in the cup with water and prepare a new dose.
  • Do not chew, cut, or crush the tablet for suspension.

Take this medicine at least 2 hours before or 6 hours after you take sucralfate, an antacid or laxative that contains aluminum, calcium, or magnesium, or a buffered medicine.

You may take calcium or iron supplements together with this medicine if you take them with food. If not, take this medicine 2 hours before or 6 hours after you take these supplements.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For HIV infection:
    • For oral dosage form (tablets):
      • Adults and children weighing 25 kilograms (kg) or more—One tablet once a day. Each tablet contains 600 milligrams (mg) abacavir, 50 mg dolutegravir, and 300 mg lamivudine.
      • Children weighing less than 25 kg—Use of tablets for suspension is recommended.
    • For oral dosage form (tablets for suspension):
      • Children weighing less than 25 kg—Dose is base on body weight and must be determined by your doctor. Each tablet contains 60 milligrams (mg) abacavir, 5 mg dolutegravir, and 30 mg lamivudine.
        • Weighing 20 kg to less than 25 kg—6 tablets (360 mg abacavir, 30 mg dolutegravir, and 180 mg lamivudine) once a day.
        • Weighing 14 kg to less than 20 kg—5 tablets (300 mg abacavir, 25 mg dolutegravir, and 150 mg lamivudine) once a day.
        • Weighing 10 kg to less than 14 kg—4 tablets (240 mg abacavir, 20 mg dolutegravir, and 120 mg lamivudine) once a day.
      • Children weighing less than 10 kg—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.