Pituitary tumor care at Mayo Clinic

Your Mayo Clinic care team

At Mayo Clinic, endocrinologists with expertise in pituitary disease coordinate a team to comprehensively evaluate pituitary tumors. Your care team may include specialists from:

Specialists from other areas can be included as needed.

Advanced diagnosis and treatment

Mayo Clinic surgeons have experience and expertise in a wide variety of treatment choices for pituitary tumors, including:

Mayo Clinic endocrinologists also are leaders in treating hormone-producing pituitary tumors and in providing pituitary hormone replacement therapy.

In Cushing syndrome, some pituitary adenomas that lead to too much adrenocorticotropic hormone, also known as ACTH, may be too small for detection with traditional MRI scans. Mayo Clinic's high-field, 3-tesla MRI scanner provides better viewing of these tumors.

Mayo Clinic's neuroradiologists are experienced in performing inferior petrosal sinus sampling to help find and identify pituitary tumors. This test involves taking a sample from the veins where the pituitary gland drains hormones into the bloodstream.

Mayo Clinic was among the first institutions to extensively research an endoscopic through-the-nose, or transnasal, surgical tumor removal technique. It has now become standard practice. This method is highly successful, lowers discomfort and usually requires only an overnight stay in the hospital.

Expertise and rankings

Nationally recognized experience

Mayo Clinic in Rochester, Minnesota, ranks No. 1 for diabetes and endocrinology in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for diabetes and endocrinology by U.S. News & World Report. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2023-2024 "Best Children's Hospitals" rankings.

Pituitary tumor expertise

Mayo Clinic is one of the largest pituitary centers in the United States. Every year, Mayo Clinic specialists evaluate and treat more than 2,600 people with pituitary tumors.

Specialized testing

A state-of-the-art facility, the Mayo Clinic Endocrine Testing Center accurately and safely performs complex hormonal stimulation and suppression tests. These tests define the nature of pituitary tumors and how well the pituitary gland is working.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.



  • Mayo Clinic Pituitary Tumor Program
  • 4500 San Pablo Road
    Jacksonville, FL 32224
  • Phone: 904-953-0818


  • Mayo Clinic Pituitary Tumor Program
  • 200 First St. SW
    Rochester, MN 55905
  • Phone: 507-284-2111