Antibiotic resistance: Understanding the connection to antibiotic use in animals raised for food
For both humans and animals, misusing and overusing antibiotics can lead to the development and spread of antibiotic-resistant bacteria that may cause untreatable infections.By Mayo Clinic Staff
Antibiotics are powerful medications designed to kill bacteria or stop its growth. However, there are times when antibiotics can actually be harmful. For both humans and animals, misusing and overusing antibiotics can lead to the development and spread of antibiotic-resistant bacteria, which in turn may lead to antibiotic-resistant infections.
All animals have bacteria in their intestines. Antibiotics that are given to food-producing animals treat infection and kill some bacteria, but resistant bacteria will often survive and multiply.
Antibiotic-resistant bacteria can then spread to:
- Other animals that are raised in the same environment
- Animal products that we eat, such as chicken and steak
- Produce, through contaminated water or soil
- The environment, through animal feces
- Prepared food, through contaminated surfaces, such as chopping vegetables on an unwashed cutting board that was used to cut raw chicken
People can become sick with antibiotic-resistant infections when they eat food that's been contaminated with antibiotic-resistant bacteria and not properly prepared, or from handling contaminated animals or surfaces and not practicing proper hand washing or environmental cleaning afterward.
Antibiotic-resistant infections can lead to mild illnesses, or in some cases, severe illnesses that may lead to death.
The U.S. Food and Drug Administration (FDA) regulates antibiotics that are used in humans and animals. In animals raised for food, FDA-approved uses of antibiotics include:
- Treating sick animals
- Controlling illness in a group of animals when some of the animals are sick
- Preventing illness in a group of animals at risk of becoming sick
- Promoting growth and weight gain
The FDA and Centers for Disease Control and Prevention recommend antibiotics that are important for human health be limited for use in food-producing animals only when it's necessary to ensure the health of the animal, not to promote growth. A doctor who treats animals (veterinarian) should oversee or advise these conditions.
July 09, 2015
See more In-depth
- Friedman M. Antibiotic-resistant bacteria: Prevalence in food and inactivation by food-compatible compounds and plant extracts. Journal of Agricultural and Food Chemistry. In press. Accessed April 13, 2015.
- Vasoo S, et al. Emerging issues in gram-negative bacterial resistance: An update for the practicing clinician. Mayo Clinic Proceedings. 2015;90(3):395.
- Tosh PK, et al. Infection control in the multidrug-resistant era: Tending the human microbiome. Clinical Infectious Diseases. 2012;54(5):707.
- Antibiotic resistance threats in the United States, 2013. Centers for Disease Control and Prevention. http://www.cdc.gov/narms/resources/threats.html. Accessed April 13, 2015.
- Antibiotic use in food-producing animals: Tracking and reducing the public health impact. Centers for Disease Control and Prevention. http://www.cdc.gov/narms/animals.html. Accessed April 13, 2015.
- Guidance for industry #213: New animal drugs and new animal drug combination products administered in or on medicated feed or drinking water of food-producing animals. U.S. Food and Drug Administration. http://www.fda.gov/AnimalVeterinary/NewsEvents/CVMUpdates/ucm435635.htm. Accessed April 13, 2015.
- Guidance for industry #209: The judicious use of medically important antimicrobial drugs in food-producing animals. U.S. Food and Drug Administration. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm299802.htm. Accessed April 13, 2015.
- Frequently asked questions about antibiotic resistance and food safety. Centers for Disease Control and Prevention. http://www.cdc.gov/narms/faq.html. Accessed April 13, 2015.