Inherited Hearing Loss By Mayo Clinic Staff Inherited Hearing Loss Your Result You are not likely to be a carrier for GJB2-related hearing loss. https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/30/no-select.png No genetic variants found https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/03/carrier.png Carrier, no signs https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/14/likely.png Likely has GJB2-related hearing loss Here's What You Need to Know This test ruled out the most common variants in the GJB2 gene. It's unlikely your children will be born with GJB2-related hearing loss. Even though this test didn't identify any variants, there is a chance that you still could be a carrier. Your risk to still be a carrier depends on your race, ethnicity, and family history. GJB2 is not the only gene that is associated with nonsyndromic hearing loss. You may have a variant in a different gene that causes nonsyndromic hearing loss, that this test is not designed to detect. Here's what you can do For most people, there's nothing more to do based on this result. If you have a family history of inherited hearing loss, you may want to consider more comprehensive testing. What will more testing tell me? Contact Us with Questions Chance of having a GJB2 genetic variant with this result: Ashkenazi Jewish 1 in 13 carry the c.167deIT GJB2 variant (7.5%) Non-Hispanic White 1 in 25 to 50 carry the c.35delG GJB2 variant (2-4%) Asian (specifically Japanese) 1 in 50-100 carry the c.235delC GJB2 variant (1-2%) African-American Carrier frequency unknown but low Hispanic White Carrier frequency unknown but low Other/Mixed Race Specific data not available Learn more About GJB2-related hearing loss About the GJB2-related hearing loss test Home Inherited Hearing Loss