Print Departments and specialties Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery. Departments that treat this condition Cornea and external eye Ophthalmology ResearchMayo Clinic's Department of Ophthalmology has a strong tradition of advanced research to improve the diagnosis and treatment of cornea disorders, and is a leader in Fuchs dystrophy research, from genetics of the disease to clinical management. The common form of Fuchs dystrophy begins in the 30s and 40s and accounts for most cases in the United States. Mayo Clinic researchers discovered that 75% of these cases were associated with a specific genetic abnormality, a trinucleotide expansion repeat in a gene called transcription factor 4 (TCF4). Researchers at Mayo Clinic and elsewhere are now using this information to discover medical therapies that might slow or stop the progression of the disease. Mayo Clinic researchers also have described how to best use imaging techniques to help manage the disease in clinical practice, and to predict the prognosis of the disease. Learn more about ongoing clinical trials at Mayo Clinic for people with Fuchs dystrophy. PublicationsSee a list of publications by Mayo Clinic authors on Fuchs dystrophy on PubMed, a service of the National Library of Medicine. Research Profiles Edit search filters close Narrow your search By location Arizona Florida Minnesota View all View all physicians • All Locations Baratz, Keith H. M.D. Minnesota Fautsch, Michael P. Ph.D. Minnesota Patel, Sanjay V. M.D. Minnesota By Mayo Clinic Staff Fuchs dystrophy care at Mayo Clinic Request an appointment Diagnosis & treatmentCare at Mayo Clinic July 13, 2024 Print Living with fuchs dystrophy? Connect with others like you for support and answers to your questions in the Transplants support group on Mayo Clinic Connect, a patient community. Transplants Discussions Anyone having issues with gaining weight after liver transplant? 24 Replies Thu, Apr 23, 2026 chevron-right 3 weeks post liver transplant: when will I feel better? 114 Replies Mon, Apr 20, 2026 chevron-right Looking for long-term Transplant success stories 33 Replies Fri, Apr 17, 2026 chevron-right See more discussions Related Fuchs dystrophy Associated Procedures Cornea transplant Products & Services A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Fuchs dystrophySymptoms&causesDiagnosis&treatmentDoctors&departmentsCare atMayoClinic Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. CON-20305527 Diseases & Conditions Fuchs dystrophy