Desmoplastic small round cell tumors care at Mayo Clinic

Mayo Clinic specialists are respected for their expertise and experience caring for people with rare cancers, including those with desmoplastic small round cell tumors.

Diagnosis at Mayo Clinic

Tests and procedures used to diagnose desmoplastic small round cell tumors include:

  • Removing a sample of tissue for testing. A biopsy procedure involves removing samples of cells from the tumor. Doctors can collect tissue samples during surgery or with a needle that's passed through the skin.

    Tissue samples are sent to a laboratory for testing. Mayo Clinic's Molecular Anatomic Pathology Laboratory conducts technical and specialized testing, including molecular genetic tests. Using the latest technology, doctors in the lab are able to make an accurate and timely diagnosis.

  • Imaging tests. Imaging tests may be used to give your doctors a better indication of the extent of your cancer and whether it involves nearby structures.

    Imaging tests may include ultrasound, CT, MRI and positron emission tomography (PET).

Treatment at Mayo Clinic

Treatment options for desmoplastic small round cell tumors include:

  • Surgery. When possible, surgeons work to remove all of the cancer. It's not always possible though, if the tumor has grown to involve nearby structures. In these cases, your doctor may recommend other treatments to shrink the tumor first.

    When it's not possible to remove the cancer entirely, your surgeon may work to remove as much of the cancer as possible.

  • Chemotherapy. Chemotherapy uses drugs to kill cancer cells. Chemotherapy may be used before surgery to shrink a tumor and make it more likely that it can be successfully removed during an operation. Chemotherapy may also be used after surgery to kill any cells that might remain after the operation.
  • Radiation therapy. Radiation therapy uses powerful energy beams, such as X-rays and protons, to kill cancer cells. Radiation therapy may be recommended after surgery to kill any cancer cells that remain.

Expertise and rankings

Your Mayo Clinic care team

At Mayo Clinic, general surgeons, oncologists, radiation oncologists, radiologists and pathologists work as a multidisciplinary team to provide whole-person care for those with desmoplastic tumors. Other professionals are included as needed.

Advanced diagnosis and treatment

Though desmoplastic small round cell tumors are rare, Mayo Clinic doctors have extensive experience diagnosing and treating these cancers.

Experts will work with you to review all of your treatment options and choose the treatment that best suits your needs and goals. The range of treatments offered to people with desmoplastic tumors includes surgery, chemotherapy and radiation therapy.

Nationally ranked expertise

Mayo Clinic doctors are respected for their expertise in diagnosing and treating rare cancers, including desmoplastic small round cell tumors.

Mayo Clinic in Rochester, Minn., Mayo Clinic in Jacksonville, Fla., and Mayo Clinic in Scottsdale, Ariz., are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic also ranks among the Best Children's Hospitals for cancer.

The Mayo Clinic Cancer Center meets strict standards for a National Cancer Institute comprehensive cancer center, which recognizes scientific excellence and a multidisciplinary approach to cancer prevention, diagnosis and treatment.

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

April 25, 2017
References
  1. Goldblum JR, et al. Malignant soft tissue tumors of an uncertain type. In: Enzinger and Weiss's Soft Tissue Tumors. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2014. http://www.clinicalkey.com. Accessed Jan. 31, 2017.
  2. Honore C, et al. Abdominal desmoplastic small round cell tumor: Multimodal treatment combining chemotherapy, surgery and radiotherapy is the best option. Annals of Surgical Oncology. 2015;22:1073.
  3. Jordan AH, et al. Management of desmoplastic small round-cell tumors in children and young adults. Journal of Pediatric Hematology/Oncology. 2012;34(suppl):S73.

Desmoplastic small round cell tumors