Malignant Hyperthermia Susceptibility By Mayo Clinic Staff Your Result You are not likely to be at increased risk of malignant hyperthermia. https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/30/no-select.png No increased risk https://www.mayoclinic.org//-/media/kcms/gbs/patient-consumer/images/2017/08/30/17/14/likely.png Increased Risk Here's What You Need to Know This test did not identify variants in the RYR1 and CACNA1S genes. You are not likely to have complications from anesthesia drugs associated with malignant hyperthermia. The variants included in this test have strong scientific evidence of their association with malignant hyperthermia. Other genes and genetic variants that may carry an increased risk of malignant hyperthermia are not included in this test. View the list of variants we test. Here's what you can do For most people, there's nothing more you need to do based on this result. If you have a personal history OR family history of malignant hyperthermia, your risk may still be increased. Talk with your health care provider about your risk. Learn more About malignant hyperthermia susceptibility About the malignant hyperthermia susceptibility test Did you know? About 1 in 2,000 patients have a genetic variant that makes them susceptible to malignant hyperthermia. Home Malignant Hyperthermia Susceptibility