Request an appointment Print Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need. U.S. patients Online requests Request an appointment at Mayo Clinic Telephone requests Mayo Clinic's campus in Rochester, Minnesota 507-284-4340 7 a.m. to 6 p.m. Central time Monday through Friday Central Appointment Office 507-538-3270 7 a.m. to 6 p.m. Central time Monday through Friday March 03, 2022 Print Share on: FacebookTwitter ORG-20458995 Medical Departments & Centers Occupational Medicine