John (Jack) C. O'Horo, M.D., M.P.H.

  1. Critical Care Specialist
  2. Infectious Disease Specialist
  3. Internist

Publications

  1. Abad CLR, Lahr B, O'Horo JC, Vijayvargiya P, Walker RC, Hogan WJ, Tande AJ. The D-index is not correlated with invasive fungal infection during the early-post engraftment phase among allogeneic hematopoietic stem cell transplant recipients. Int J Hematol. 2019 Nov 11 [Epub ahead of print]
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  2. Daniels LM, Durani U, Barreto JN, O'Horo JC, Siddiqui MA, Park JG, Tosh PK. Impact of time to antibiotic on hospital stay, intensive care unit admission, and mortality in febrile neutropenia. Support Care Cancer. 2019 Nov; 27 (11):4171-4177 Epub 2019 Feb 25
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  3. Shah AS, O'Horo JC, Tang S, Bryson AL, Wengenack NL, Sampathkumar P. Fungal Diagnostic Stewardship in Bronchoscopy Specimens for Immunocompetent Patients in the Intensive Care Unit. Mayo Clin Proc. 2019 Sep; 94 (9):1781-1785 Epub 2019 Aug 07
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  4. O'Horo JC, Marcelin JR, Abu Saleh OM, Barwise AK, Odean PM, Rivera CG, Tande AJ, Wilson JW, Osmon DR, Tosh PK. Standardizing Febrile Neutropenia Management: Antimicrobial Stewardship in the Hematologic Malignancy Population. J Oncol Pract. 2019 Sep; 15 (9):e843-e848 Epub 2019 July 19
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  5. Vallabhajosyula S, O'Horo JC, Antharam P, Ananthaneni S, Vallabhajosyula S, Stulak JM, Dunlay SM, Holmes DR Jr, Barsness GW. Venoarterial Extracorporeal Membrane Oxygenation With Concomitant Impella Versus Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock. ASAIO J. 2019 Jul 17 Epub 2019 July 17
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  6. Fida M, Challener D, Hamdi A, O'horo J, Abu Saleh O. Babesiosis: A Retrospective Review of 38 Cases in the Upper Midwest. Open Forum Infect Dis. 2019 Jul 1; 6 (7)
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  7. Mahmood M, Kendi AT, Ajmal S, Farid S, O'Horo JC, Chareonthaitawee P, Baddour LM, Sohail MR. Meta-analysis of 18F-FDG PET/CT in the diagnosis of infective endocarditis. J Nucl Cardiol. 2019 Jun; 26 (3):922-935 Epub 2017 Oct 30
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  8. Yetmar ZA, Lahr B, O'Horo J, Behfar A, Sampathkumar P, Beam E. Pulmonary artery catheter epidemiology of risk in pre-heart-transplant recipients. Infect Control Hosp Epidemiol. 2019 Jun; 40 (6):632-638 Epub 2019 Apr 30
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  9. Musuuza JS, Guru PK, O'Horo JC, Bongiorno CM, Korobkin MA, Gangnon RE, Safdar N. The impact of chlorhexidine bathing on hospital-acquired bloodstream infections: a systematic review and meta-analysis. BMC Infect Dis. 2019 May 14; 19 (1):416
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  10. Kashyap R, Singh TD, Rayes H, O'Horo JC, Wilson G, Bauer P, Gajic O. Association of septic shock definitions and standardized mortality ratio in a contemporary cohort of critically ill patients. J Crit Care. 2019 Apr; 50:269-274 Epub 2019 Jan 11
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  11. Sakusic A, Gajic O, Singh TD, O'Horo JC, Jenkins G, Wilson GA, Petersen R, Fryer JD, Kashyap R, Rabinstein AA. Risk Factors for Persistent Cognitive Impairment After Critical Illness, Nested Case-Control Study. Crit Care Med. 2018 Dec; 46 (12):1977-1984
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  12. Bauer PR, O'Horo JC. Ventilator-Associated Pneumonia: Are the Antibiotics the Solution? Crit Care Med 2018 Oct; 46 (10):1703-1705
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  13. Vallabhajosyula S, O'Horo JC, Antharam P, Ananthaneni S, Vallabhajosyula S, Stulak JM, Eleid MF, Dunlay SM, Gersh BJ, Rihal CS, Barsness GW. Concomitant Intra-Aortic Balloon Pump Use in Cardiogenic Shock Requiring Veno-Arterial Extracorporeal Membrane Oxygenation. Circ Cardiovasc Interv. 2018 Sep; 11 (9):e006930
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  14. O'Horo JC, Dziadzko M, Sakusic A, Ali R, Sohail MR, Kor DJ, Gajic O. Seeking out SARI: an automated search of electronic health records. Epidemiol Infect. 2018 Jun; 146 (8):1065-1069 Epub 2018 Apr 18
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  15. O'Horo JC, Abu Saleh OM, Stulak JM, Wilhelm MP, Baddour LM, Rizwan Sohail M, Sohail MR. Left Ventricular Assist Device Infections: A Systematic Review. ASAIO J. 2018 May/Jun; 64 (3):287-294
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  16. Sevilla-Berrios R, O'Horo JC, Schmickl CN, Erdogan A, Chen X, Garcia Arguello LY, Dong Y, Kilickaya O, Pickering B, Kashyap R, Gajic O. Prompting with electronic checklist improves clinician performance in medical emergencies: a high-fidelity simulation study. Int J Emerg Med. 2018 Apr 27; 11 (1):26
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  17. Sims JR, Anavekar NS, Bhatia S, O'Horo JC, Geske JB, Chandrasekaran K, Wilson WR, Baddour LM, Gersh BJ, DeSimone DC. Clinical, Radiographic, and Microbiologic Features of Infective Endocarditis in Patients With Hypertrophic Cardiomyopathy. Am J Cardiol. 2018 Feb 15; 121 (4):480-484 Epub 2017 Nov 23
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  18. Singh TD, O'Horo JC, Gajic O, Sakusic A, Day CN, Mandrekar J, Kashyap R, Reddy DRS, Rabinstein AA. Risk factors and outcomes of critically ill patients with acute brain failure: A novel end point. J Crit Care. 2018 Feb; 43:42-47 Epub 2017 Aug 18
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  19. Sakusic A, O'Horo JC, Dziadzko M, Volha D, Ali R, Singh TD, Kashyap R, Farrell AM, Fryer JD, Petersen R, Gajic O, Rabinstein AA. Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review. Mayo Clin Proc. 2018 Jan; 93 (1):68-82
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  20. Shah A, O'Horo JC, Wilson JW, Granger D, Theel ES. An Unusual Cluster of Neuroinvasive Lyme Disease Cases Presenting With Bannwarth Syndrome in the Midwest United States. Open Forum Infect Dis. 2018 Jan; 5 (1):ofx276 Epub 2017 Dec 23
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  21. Gallo de Moraes A, O'Horo JC, Sevilla-Berrios RA, Iacovella G, Lenhertz A, Schmidt J, Elmer J, Oeckler R, Caples S, Jensen JB. Expanding the Presence of Primary Services at Rapid Response Team Activations: A Quality Improvement Project. Qual Manag Health Care. 2018 Jan/Mar; 27 (1):50-55
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  22. O'Horo JC, Harper EP, El Rafei A, Ali R, DeSimone DC, Sakusic A, Abu Saleh OM, Marcelin JR, Tan EM, Rao AK, Sobel J, Tosh PK. Efficacy of Antitoxin Therapy in Treating Patients With Foodborne Botulism: A Systematic Review and Meta-analysis of Cases, 1923-2016. Clin Infect Dis. 2017 Dec 27; 66 (suppl_1):S43-S56
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  23. O'Horo JC, Sampathkumar P. Infections in Neurocritical Care. Neurocrit Care. 2017 Dec; 27 (3):458-467
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  24. Kogan A, Pennington KM, Vallabhajosyula S, Dziadzko M, Bennett CE, Jensen JB, Gajic O, O'Horo JC. Reliability and Validity of the Checklist for Early Recognition and Treatment of Acute Illness and Injury as a Charting Tool in the Medical Intensive Care Unit. Indian J Crit Care Med. 2017 Nov; 21 (11):746-750
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  25. Olchanski N, Dziadzko MA, Tiong IC, Daniels CE, Peters SG, O'Horo JC, Gong MN. Can a Novel ICU Data Display Positively Affect Patient Outcomes and Save Lives? J Med Syst. 2017 Sep 18; 41 (11):171 Epub 2017 Sept 18
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  26. O'Horo JC, Osmon DR, Abu Saleh OM, Marcelin JR, Gharaibeh KA, Hamadah AM, Barwise AK, Kayhart BM, McDonald JS, McDonald RJ, Leung N. Coadministration of Liposomal Amphotericin B and Contrast Medium Does Not Increase Risk of Kidney Injury. Antimicrob Agents Chemother. 2017 Aug; 61 (8) Epub 2017 July 25
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  27. Hoskote SS, Racedo Africano CJ, Braun AB, O'Horo JC, Sevilla Berrios RA, Loftsgard TO, Bryant KM, Iyer VN, Smischney NJ. Improving the Quality of Handoffs in Patient Care Between Critical Care Providers in the Intensive Care Unit. Am J Med Qual. 2017 Jul/Aug; 32 (4):376-383 Epub 2016 June 20
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  28. Garcia-Arguello LY, O'Horo JC, Farrell A, Blakney R, Sohail MR, Evans CT, Safdar N. Infections in the spinal cord-injured population: a systematic review. Spinal Cord. 2017 Jun; 55 (6):526-534 Epub 2016 Dec 06
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  29. Iyer AS, O'Horo JC, Thompson R. Purpura from a Tick Bite. Am J Med. 2017 Apr; 130 (4):e131-e132 Epub 2016 Dec 21
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  30. Amra S, O'Horo JC, Singh TD, Wilson GA, Kashyap R, Petersen R, Roberts RO, Fryer JD, Rabinstein AA, Gajic O. Derivation and validation of the automated search algorithms to identify cognitive impairment and dementia in electronic health records. J Crit Care. 2017 Feb; 37:202-205 Epub 2016 Oct 08
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  31. Ellsworth MA, Dziadzko M, O'Horo JC, Farrell AM, Zhang J, Herasevich V. An appraisal of published usability evaluations of electronic health records via systematic review. J Am Med Inform Assoc. 2017 Jan; 24 (1):218-226 Epub 2016 Apr 23
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  32. Velagapudi V, O'Horo JC, Vellanki A, Baker SP, Pidikiti R, Stoff JS, Tighe DA. Computer-assisted image processing 12 lead ECG model to diagnose hyperkalemia. J Electrocardiol. 2017 Jan - Feb; 50 (1):131-138 Epub 2016 Sept 09
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  33. O'Horo JC, Lan H, Thongprayoon C, Schenck L, Ahmed A, Dziadzko M, Gajic O, Sampathkumar P. "Bundle" Practices and Ventilator-Associated Events: Not Enough. Infect Control Hosp Epidemiol. 2016 Dec; 37 (12):1453-1457 Epub 2016 Sept 19
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  34. Guru PK, O Horo JC, Lehrke HD, Winters JL, Wilson JW. Exchange transfusion for babesiosis when, how, and how long? Indian J Crit Care Med. 2016 Nov; 20 (11):674-676
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  35. O'Horo JC, Farrell A, Sohail MR, Safdar N. Carbapenem-resistant Enterobacteriaceae and endoscopy: An evolving threat. Am J Infect Control. 2016 Sep 1; 44 (9):1032-6 Epub 2016 May 11
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  36. Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA. Identification of acute brain failure using electronic medical records. J Crit Care. 2016 Aug; 34:12-6 Epub 2016 Mar 16
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  37. O'Horo JC, Kashyap R, Sevilla Berrios R, Herasevich V, Sampathkumar P. Differentiating infectious and noninfectious ventilator-associated complications: A new challenge. Am J Infect Control. 2016 Jun 1; 44 (6):661-5 Epub 2016 Feb 18
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  38. Birkenkamp K, O'Horo JC, Kashyap R, Kloesel B, Lahr BD, Daniels CE, Nichols FC 3rd, Baddour LM. Empyema management: A cohort study evaluating antimicrobial therapy. J Infect. 2016 May; 72: (5)537-43.
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  39. Thongprayoon C, Harrison AM, O'Horo JC, Berrios RA, Pickering BW, Herasevich V. The Effect of an Electronic Checklist on Critical Care Provider Workload, Errors, and Performance. J Intensive Care Med. 2016 Mar; 31: (3)205-12.
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  40. Erdogan A, Dong Y, Chen X, Schmickl C, Sevilla Berrios RA, Garcia Arguello LY, Kashyap R, Kilickaya O, Pickering B, Gajic O, O'Horo JC. Development and validation of clinical performance assessment in simulated medical emergencies: an observational study. BMC Emerg Med. 2016 Jan 15; 16:4
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  41. O'Horo JC, Cawcutt KA, De Moraes AG, Sampathkumar P, Schears GJ. The Evidence Base for Prophylactic Antibiotics in Patients Receiving Extracorporeal Membrane Oxygenation. ASAIO J. 2016 Jan-Feb; 62: (1)6-10.
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  42. Tedja R, Wentink J, O'Horo JC, Thompson R, Sampathkumar P. Catheter-Associated Urinary Tract Infections in Intensive Care Unit Patients. Infect Control Hosp Epidemiol. 2015 Nov; 36: (11)1330-4.
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  43. Blakney R, Gudnadottir U, Warrack S, O'Horo JC, Anderson M, Sethi A, Schmitz M, Wang J, Duster M, Ide E, Safdar N. The relationship between patient functional status and environmental contamination by Clostridium difficile: a pilot study. Infection. 2015 Aug; 43(4):483-7. Epub 2015 Apr 14.
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  44. Thompson G, O'Horo JC, Pickering BW, Herasevich V. Impact of the Electronic Medical Record on Mortality, Length of Stay, and Cost in the Hospital and ICU: A Systematic Review and Metaanalysis. Crit Care Med. 2015 Jun; 43 (6):1276-82
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  45. O'Horo JC, Rogus-Pulia N, Garcia-Arguello L, Robbins J, Safdar N. Bedside diagnosis of dysphagia: a systematic review. J Hosp Med. 2015 Apr; 10 (4):256-65 Epub 2015 Jan 12
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  46. O'Horo JC, Sevilla Berrios RA, Elmer JL, Velagapudi V, Caples SM, Kashyap R, Jensen JB. The role of the primary care team in the rapid response system. J Crit Care. 2015 Apr; 30 (2):353-7 Epub 2014 Oct 30
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  47. Lan H, Thongprayoon C, Ahmed A, Herasevich V, Sampathkumar P, Gajic O, O'Horo JC. Automating Quality Metrics in the Era of Electronic Medical Records: Digital Signatures for Ventilator Bundle Compliance. Biomed Res Int. 2015; 2015:396508 Epub 2015 June 08
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  48. Sevilla Berrios RA, O'Horo JC, Velagapudi V, Pulido JN. Correlation of left ventricular systolic dysfunction determined by low ejection fraction and 30-day mortality in patients with severe sepsis and septic shock: a systematic review and meta-analysis. J Crit Care. 2014 Aug; 29 (4):495-9 Epub 2014 Mar 21
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  49. Smischney NJ, Cawcutt KA, O'Horo JC, Sevilla Berrios RA, Whalen FX. Intensive care unit readmission prevention checklist: is it worth the effort? J Eval Clin Pract. 2014 Aug; 20(4):348-51. Epub 2014 Apr 29.
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  50. Safdar N, O'Horo JC, Ghufran A, Bearden A, Didier ME, Chateau D, Maki DG. Chlorhexidine-impregnated dressing for prevention of catheter-related bloodstream infection: a meta-analysis*. Crit Care Med. 2014 Jul; 42 (7):1703-13
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  51. O'Horo JC, Maki DG, Krupp AE, Safdar N. Arterial catheters as a source of bloodstream infection: a systematic review and meta-analysis. Crit Care Med. 2014 Jun; 42 (6):1334-9
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  52. O'Horo JC, Jindai K, Kunzer B, Safdar N. Treatment of recurrent Clostridium difficile infection: a systematic review. Infection. 2014 Feb; 42 (1):43-59 Epub 2013 July 10
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  53. Safdar N, O'Horo JC, Maki DG. Arterial catheter-related bloodstream infection: incidence, pathogenesis, risk factors and prevention. J Hosp Infect. 2013 Nov; 85(3):189-95. Epub 2013 Sep 23.
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  54. Chopra V, O'Horo JC, Rogers MA, Maki DG, Safdar N. The risk of bloodstream infection associated with peripherally inserted central catheters compared with central venous catheters in adults: a systematic review and meta-analysis. Infect Control Hosp Epidemiol. 2013 Sep; 34(9):908-18. Epub 2013 Jul 26.
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  55. Chlebicki MP, Safdar N, O'Horo JC, Maki DG. Preoperative chlorhexidine shower or bath for prevention of surgical site infection: a meta-analysis. Am J Infect Control. 2013 Feb; 41(2):167-73. Epub 2012 Jun 19.
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  56. Kashiouris M, O'Horo JC, Pickering BW, Herasevich V. Diagnostic performance of electronic syndromic surveillance systems in acute care: a systematic review. Appl Clin Inform. 2013; 4 (2):212-24 Epub 2013 May 08
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  57. Safdar N, O'Horo JC, Mak R, Medow J. Agreement between the clinical pulmonary infection score and NHSN criteria for surveillance of ventilator associated pneumonia International Journal of Infection Control. 2013; 9: (1)10817.
  58. O'Horo JC, Thompson D, Safdar N. Is the gram stain useful in the microbiologic diagnosis of VAP? A meta-analysis. Clin Infect Dis. 2012 Aug; 55(4):551-61. Epub 2012 Jun 07.
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  59. O'Horo JC, Jones A, Sternke M, Harper C, Safdar N. Molecular techniques for diagnosis of Clostridium difficile infection: systematic review and meta-analysis. Mayo Clin Proc. 2012 Jul; 87(7):643-51.
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  60. Brauer E, O'Horo JC. An acute, progressive encephalopathy. WMJ. 2012 Apr; 111(2):66-7.
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  61. O'Horo JC, Silva GL, Munoz-Price LS, Safdar N. The efficacy of daily bathing with chlorhexidine for reducing healthcare-associated bloodstream infections: a meta-analysis. Infect Control Hosp Epidemiol. 2012 Mar; 33(3):257-67. Epub 2012 Jan 25.
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  62. O'Horo JC, Andreev M, Hassan W, Anwar A. Evaluating traditional prognostic measures in patients undergoing hypothermia after cardiac arrest. Ther Hypothermia Temp Manag. 2012 Mar; 2: (1)24-9.
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  63. O'Horo JC, Omballi M, Tran TK, Jordan JP, Baumgardner DJ, Gennis MA. Effect of audit and feedback on improving handovers: a nonrandomized comparative study. J Grad Med Educ. 2012 Mar; 4: (1)42-6.
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  64. Wang D, O'Horo J. Antifibrotic effects of omega-3 fatty acids in the heart: one possible treatment for diastolic heart failure. Trends Cardiovasc Med. 2011 Apr; 21(3):90-5.
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  65. O'Horo JC, Silva GL, Safdar N. Anti-infective locks for treatment of central line-associated bloodstream infection: a systematic review and meta-analysis. Am J Nephrol. 2011; 34(5):415-22. Epub 2011 Sep 21.
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  66. O'Horo J, Safdar N. The role of immunoglobulin for the treatment of Clostridium difficile infection: a systematic review. Int J Infect Dis. 2009 Nov; 13(6):663-7. Epub 2009 Jan 30.
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PST-20215920