Wayne L. Miller, M.D., Ph.D.

Wayne L. Miller, MD, PhD is a board-certified cardiologist and staff member of the Mayo Clinic Department of Cardiovascular Medicine, Professor of Medicine, Mayo Clinic College of Medicine, and member of the Mayo Heart Failure Clinic and Research Group. He attended Jefferson Medical College at Thomas Jefferson University, Philadelphia, PA and specialty training in internal medicine and cardiovascular diseases at Mayo Clinic, Rochester, MN. Research training has included a 3-year National Institutes of Health post-doctoral fellowship at the University of Virginia (Dr. Robert Berne's laboratory) in basic research studying myocardial physiology and myocardial metabolism and energetics and an NIH fellowship at the Mayo Clinic (Dr. John Burnett’s laboratory) pursuing research in cardio-renal physiology and mechanisms of heart failure disease. Research and clinical interests focus on heart failure both chronic and acute with assessment of the pathophysiologic roles of clinical biomarkers and also interstitial and intravascular volume congestion in patients with chronic heart failure and cardio-renal syndrome. Subsequent clinical and basic research has branched to assessing neurohormonal biomarkers of cardiac function (cardiac natriuretic peptides ANP and BNP/NT-pro BNP). Ongoing novel studies have been directed at assessing the clinical significance and prognostic contribution of intravascular volume overload and it heterogeneity in relation to neurhormonal activation and renal function in patients with chronic heart failure. Clinical expertise focuses mainly on the practice of heart failure cardiology, mainly with patients experiencing advanced heart failure and patients with cardiac complications of amyloidosis. Additional professional time is spent in resident/cardiology fellow education, as well as, clinical research working with heart failure patients.