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Dacre Knight, M.D.

  1. Internist


  1. Jacksonville, Florida



Dacre Knight, M.D., is a general internal medicine physician, with specialty interest in consultative and diagnostic medicine. His clinical focus includes:

  • Expertise in management of chronic diseases for both international and domestic patients
  • Comprehensive evaluation and diagnosis of unresolved illness
  • Providing coordinated care for Ehlers-Danlos Syndrome patients, offering personalized diagnostic evaluation, and treatment catered to the unique needs of each patient
  • Promoting each patient's understanding of disease and empowering patients to reach their individual health goals
  • Improving medical literacy and communication risks to prevent chronic disease

Dr. Knight is board certified in internal medicine. In addition to his clinical activities, Dr. Knight is active in research and education, providing mentorship to residents and students.

Prior to joining Mayo Clinic, Dr. Knight was an Assistant Professor of Medicine at Saint Louis University. He also served 4 years as an Air Force physician at Scott Air Force Base, Illinois. He was Director of the Phase II Clinical Laboratory education program, and Chairman of the Life Support Function Committee. In addition, he served overseas deployment for 7 months in Afghanistan with NATO Operation Resolute Support. He was Chairman of the hospital Infection Control Committee. He briefed command staff on biodefense exercises, and managed combat trauma patients.

Dr. Knight has diverse research interests, including treatment of complex patients using the latest technological advances, such as machine learning, and artificial intelligence.

Dr. Knight is married, and a father of three children. He is a former NCAA Division III Collegiate Soccer athlete, and a traveling enthusiast.

  1. 2015
    Residency - Internal MedicineUniversity of Mississippi Medical Center
  2. 2012
    MDSt. George's University Medical School
  3. 2009
    Medical School - Diploma Health StudiesUniversity of Northumbria
  4. 2006
    MS - Biodefense; Master’s thesis: novel detection methods for Bioterror events using mass spectroscopy to investigate antibody activity of Vaccinia virus as a platform for smallpox infection.George Mason University
  5. 2005
    BS with Distinction - Biology, Honors research on antimicrobial activity of Honokiol, a small molecular-weight phytochemical compound. Minor in French LanguageHampden-Sydney College
  6. 2003
    Pre-Medical - Undergraduate International StudiesUniversity of St. Andrews


  1. 2015
    Internal MedicineAmerican Board of Internal Medicine

Awards and honors

  1. 2021
    Mayo Clinic Quality Review Board Outstanding Project for 2020. Mayo Clinic Quality Academy
  2. 2020
    Department of Medicine Procedural Innovation Team Annual Award Department of Medicine Division
  3. 2019
    Air Force Commendation MedalUnited States Air Force
  4. 2017
    Air Force Meritorious Unit AwardUnited States Air Force
  5. 2017
    Outstanding Clinical Educator Award for a Faculty Member in Inpatient MedicineSchool of Medicine, St. Louis University
  6. 2005
    Honor's Research in BiologyHonors in Biology
  7. 2004
    Jas T. Hewitt Award for Excellence in BiologyDepartment of Biological Sciences, Hampden-Sydney College
  8. 2004
    Pre-Medical ScholarHampden-Sydney College
  9. 2003
    James Madison Honors ScholarHampden-Sydney College

Professional memberships

  1. 2020 - present
    Active MemberSOAR MERG
  2. 2020 - present
    Active MemberDigital Innovation Lab
  3. 2019 - present
    Active MemberMayo Medical Education and Research Group (MERG), Mayo Clinic Task Forces/Work Groups
  4. 2019 - present
    MemberAmerican College of Physicians
  5. 2017 - 2019
    Chairman - Life Support Function CommitteeUnited States Air Force
  6. 2005 - present
    Member, Nominating CommitteeChi Beta Phi National Science Honorary Society
  7. 2005 - present
    MemberOmicron Delta Kappa National Leadership
  8. 2004 - present
    MemberPhi Sigma Iota International Foreign Language Honor Society


Research activities

See a description of research activities.