Search for a doctor

Matthew T. Drake, M.D., Ph.D.

  1. Endocrinologist

Publications

  1. Dutta A, Ferrero A, Rajendran K, Drake MT, Ou FS, Giri S, Fletcher JG, McCollough CH, Baffour FI. Correction to: Quantitative metrics of bone quality determined at the distal radius using photon‑counting CT. Skeletal Radiol. 2024 Sep 17 Epub 2024 Sept 17
    View PubMed
  2. Farr JN, Atkinson EJ, Achenbach SJ, Volkman TL, Tweed AJ, Vos SJ, Ruan M, Sfeir J, Drake MT, Saul D, Doolittle ML, Bancos I, Yu K, Tchkonia T, LeBrasseur NK, Kirkland JL, Monroe DG, Khosla S. Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial. Nat Med. 2024 Sep; 30 (9):2605-2612 Epub 2024 July 02
    View PubMed
  3. Dutta A, Ferrero A, Rajendran K, Drake MT, Ou FS, Giri S, Fletcher JG, McCollough CH, Baffour FI. Quantitative metrics of bone quality determined at the distal radius using photon-counting CT. Skeletal Radiol. 2024 Aug 9 Epub 2024 Aug 09
    View PubMed
  4. Drake MT. Optimising zoledronate treatment holiday duration without loss of fracture prevention. Lancet Diabetes Endocrinol. 2024 Apr; 12 (4):217-219 Epub 2024 Mar 04
    View PubMed
  5. Lee RH, Curtis J, Drake MT, Bobo Tanner S 4th, Lenert L, Schmader K, Pieper C, North R, Lyles KW. Association of prior treatment with nitrogen-containing bisphosphonates on outcomes of COVID-19 positive patients. Osteoporos Int. 2024 Jan; 35 (1):181-187 Epub 2023 Sept 13
    View PubMed
  6. Cawthon PM, Drake M. It is not "just a fracture". JBMR Plus. 2024; 8 (5):ziae022
  7. Mc Donald D, Drake MT, Crowley RK. Treatment of hypercalcaemia of malignancy in adults. Clin Med (Lond). 2023 Sep; 23 (5):503-507
    View PubMed
  8. Mc Donald D, Drake MT, Crowley RK. Treatment of hypercalcaemia of malignancy in adults. Clin Med (Lond). 2023 Sep; 23 (5):503-507 Epub 2023 Sept 29
    View PubMed
  9. Clinical manifestations, diagnosis, and treatment of osteomalacia UpToDate. 2023.
  10. Epidemiology and etiology of osteomalacia UpToDate. 2023.
  11. El-Hajj Fuleihan G, Drake MT. Commentary on the endocrine society clinical practice guideline on the "treatment of hypercalcemia of malignancy in adults". Metabolism 2023 Jun; 143:155553 Epub 2023 Apr 05
    View PubMed
  12. Ho M, Dasari S, Visram A, Drake MT, Charlesworth MC, Johnson KL, Pujari GP, Jevremovic D, Kourelis T. An atlas of the bone marrow bone proteome in patients with dysproteinemias. Blood Cancer J. 2023 Apr 28; 13 (1):63
    View PubMed
  13. Seisa MO, Nayfeh T, Hasan B, Firwana M, Saadi S, Mushannen A, Shah SH, Rajjoub NS, Farah MH, Prokop LJ, Wang Z, Fuleihan GE, Drake MT, Murad MH. A Systematic Review Supporting the Endocrine Society Clinical Practice Guideline on the Treatment of Hypercalcemia of Malignancy in Adults. J Clin Endocrinol Metab. 2023 Feb 15; 108 (3):585-591
    View PubMed
  14. Bassatne A, Murad MH, Piggott T, Drake MT, Rahme M, El-Hajj Fuleihan G. Patient and Physician Decisional Factors Regarding Hypercalcemia of Malignancy Treatment: A Novel Mixed-Methods Study. J Clin Endocrinol Metab. 2023 Feb 15; 108 (3):563-584
    View PubMed
  15. El-Hajj Fuleihan G, Clines GA, Hu MI, Marcocci C, Murad MH, Piggott T, Van Poznak C, Wu JY, Drake MT. Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2023 Feb 15; 108 (3):507-528
    View PubMed
  16. Nasr JT, Tohme J, Collins MT, Drake MT, Hartley IR, Sfeir J, Dockery K, Taskin M. Tumour-induced osteomalacia: a rare cause of chronic pain and weakness. Pract Neurol. 2022 Dec; 22 (6):528-531 Epub 2022 July 27
    View PubMed
  17. Nasr JT, Tohme J, Collins MT, Drake MT, Hartley IR, Sfeir J, Dockery K, Taskin M. Tumour-induced osteomalacia: a rare cause of chronic pain and weakness. Pract Neurol. 2022 Dec; 22(6):528-531. Epub 2022 Jul 27.
    View PubMed
  18. Lewiecki EM, Bilezikian JP, Binkley N, Bouxsein ML, Bukata SV, Dempster DW, Drake MT, McClung MR, Miller PD, Rosenthal E, Tosi LL. Proceedings of the 2022 Santa Fe Bone Symposium: Current Concepts in the Care of Patients with Osteoporosis and Metabolic Bone Diseases. J Clin Densitom. 2022 Oct-Dec; 25 (4):649-667 Epub 2022 Oct 15
    View PubMed
  19. McCartney CR, Corrigan MD, Drake MT, El-Hajj Fuleihan G, Korytkowski MT, Lash RW, Lieb DC, McCall AL, Muniyappa R, Piggott T, Santesso N, Schunemann HJ, Wiercioch W, McDonnell ME, Murad MH. Enhancing the Trustworthiness of the Endocrine Society's Clinical Practice Guidelines. J Clin Endocrinol Metab. 2022 Jul 14; 107 (8):2129-2138
    View PubMed
  20. Sfeir JG, Drake MT, Khosla S, Farr JN. Skeletal Aging. Mayo Clin Proc. 2022 Jun; 97 (6):1194-1208
    View PubMed
  21. Tsourdi E, Drake MT. Pros and Cons of Skeletal Medications in the COVID-19 Era. Curr Treatm Opt Rheumatol. 2022; 8 (3):56-69 Epub 2022 July 16
    View PubMed
  22. Muchtar E, Drake MT, Leung N, Dispenzieri A, Lacy MQ, Buadi FK, Dingli D, Hayman SR, Kapoor P, Hwa YL, Fonder A, Hobbs M, Gonsalves W, Kourelis TV, Warsame R, Russell S, Go RS, Binder M, Kyle RA, Rajkumar SV, Kumar SK, Gertz MA. Hypovitaminosis D Is Prevalent in Patients With Renal AL Amyloidosis and Associated With Renal Outcome. Front Endocrinol (Lausanne). 2022; 13:891712 Epub 2022 June 21
    View PubMed
  23. Salaami O, Kuo CL, Drake MT, Kuchel GA, Kirkland JL, Pignolo RJ. Antidiabetic Effects of the Senolytic Agent Dasatinib. Mayo Clin Proc. 2021 Dec; 96 (12):3021-3029 Epub 2021 Nov 09
    View PubMed
  24. Berger MG, Pandian TK, Lyden ML, McKenzie T, Drake MT, Dy BM. Preoperative Imaging in Renal Transplant Patients with Tertiary Hyperparathyroidism. World J Surg. 2021 Aug; 45 (8):2454-2462 Epub 2021 Mar 27
    View PubMed
  25. Tsourdi E, Yu EW, Jan de Beur SM, Drake MT. Vaccination for Coronavirus Disease 2019 (COVID-19) and Relationship to Osteoporosis Care: Current Evidence and Suggested Approaches. J Bone Miner Res. 2021 Jun; 36 (6):1042-1047 Epub 2021 Apr 14
    View PubMed
  26. Saul D, Drake MT. Update on Approved Osteoporosis Therapies Including Combination and Sequential Use of Agents. Endocrinol Metab Clin North Am. 2021 Jun; 50 (2):179-191
    View PubMed
  27. Clinical manifestations, diagnosis, and treatment of osteomalacia UpToDate. 2021.
  28. Terpos E, Zamagni E, Lentzsch S, Drake MT, Garcia-Sanz R, Abildgaard N, Ntanasis-Stathopoulos I, Schjesvold F, de la Rubia J, Kyriakou C, Hillengass J, Zweegman S, Cavo M, Moreau P, San-Miguel J, Dimopoulos MA, Munshi N, Durie BGM, Raje N, Bone Working Group of the International Myeloma Working Group. Treatment of multiple myeloma-related bone disease: recommendations from the Bone Working Group of the International Myeloma Working Group. Lancet Oncol. 2021 Mar; 22 (3):e119-e130 Epub 2021 Feb 02
    View PubMed
  29. Kennel KA, Sfeir JG, Drake MT. Optimizing DXA to Assess Skeletal Health: Key Concepts for Clinicians. J Clin Endocrinol Metab. 2020 Dec 1; 105 (12)
    View PubMed
  30. Samakkarnthai P, Sfeir JG, Atkinson EJ, Achenbach SJ, Wennberg PW, Dyck PJ, Tweed AJ, Volkman TL, Amin S, Farr JN, Vella A, Drake MT, Khosla S. Determinants of Bone Material Strength and Cortical Porosity in Patients with Type 2 Diabetes Mellitus. J Clin Endocrinol Metab. 2020 Oct 1; 105 (10):e3718-29
    View PubMed
  31. Sfeir JG, Pena Guzman TD, Bedatsova L, Broski SM, Drake MT. Use of trabecular bone score for risk stratification of patients with monoclonal gammopathy of undetermined significance. Bone. 2020 Aug; 137:115394 Epub 2020 Apr 28
    View PubMed
  32. Compston JE, Drake MT. Defining Very High Fracture Risk: Is FRAX Fit for Purpose? J Bone Miner Res. 2020 Aug; 35 (8):1399-1403 Epub 2020 July 31
    View PubMed
  33. Yu EW, Tsourdi E, Clarke BL, Bauer DC, Drake MT. Osteoporosis Management in the Era of COVID-19. J Bone Miner Res 2020 Jun; 35 (6):1009-1013 Epub 2020 May 26
    View PubMed
  34. Athimulam S, Delivanis D, Thomas M, Young WF, Khosla S, Drake MT, Bancos I. The Impact of Mild Autonomous Cortisol Secretion on Bone Turnover Markers. J Clin Endocrinol Metab. 2020 May 1; 105 (5):1469-77
    View PubMed
  35. Ravindran A, Lackore KA, Glasgow AE, Drake MT, Hobbs MA, Kourelis T, Kumar S, Kyle RA, Leung N, Muchtar E, Go RS. Monoclonal Gammopathy of Undetermined Significance: Indications for Prediagnostic Testing, Subsequent Diagnoses, and Follow-up Practice at Mayo Clinic. Mayo Clin Proc. 2020 May; 95 (5):944-954
    View PubMed
  36. O'Grady KL, Khosla S, Farr JN, Bondar OP, Atkinson EJ, Achenbach SJ, Eckhardt BA, Thicke BS, Tweed AJ, Volkman TL, Drake MT, Hines JM, Singh RJ. Development and Application of Mass Spectroscopy Assays for Nepsilon-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes. J Appl Lab Med. 2020 May 1; 5 (3):558-568
    View PubMed
  37. Morris EV, Suchacki KJ, Hocking J, Cartwright R, Sowman A, Gamez B, Lea R, Drake MT, Cawthorn WP, Edwards CM. Myeloma Cells Down-Regulate Adiponectin in Bone Marrow Adipocytes Via TNF-Alpha. J Bone Miner Res. 2020 May; 35 (5):942-955 Epub 2020 Jan 16
    View PubMed
  38. O'Keefe RJ, Tuan RS, Lane NE, Awad HA, Barry F, Bunnell BA, Colnot C, Drake MT, Drissi H, Dyment NA, Fortier LA, Guldberg RE, Kandel R, Little DG, Marshall MF, Mao JJ, Nakamura N, Proffen BL, Rodeo SA, Rosen V, Thomopoulos S, Schwarz EM, Serra R. American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies - Secondary Publication. J Orthop Res. 2020 Mar; 38 (3):485-502 Epub 2020 Jan 29
    View PubMed
  39. Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL, Oursler MJ, Khosla S. Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nat Commun. 2020 Jan 7; 11 (1):87 Epub 2020 Jan 07
    View PubMed
  40. O'Keefe RJ, Tuan RS, Lane NE, Awad HA, Barry F, Bunnell BA, Colnot C, Drake MT, Drissi H, Dyment NA, Fortier LA, Guldberg RE, Kandel R, Little DG, Marshall MF, Mao JJ, Nakamura N, Proffen BL, Rodeo SA, Rosen V, Thomopoulos S, Schwarz EM, Serra R. American Society for Bone and Mineral Research-Orthopaedic Research Society Joint Task Force Report on Cell-Based Therapies. J Bone Miner Res. 2020 Jan; 35 (1):3-17 Epub 2019 Sept 23
    View PubMed
  41. Berent TE, Dorschner JM, Craig TA, Drake MT, Westendorf JJ, Kumar R. Lung tumor cells inhibit bone mineralization and osteoblast activity. Biochem Biophys Res Commun. 2019 Nov 12; 519 (3):566-571 Epub 2019 Sept 16
    View PubMed
  42. Bedatsova L, Drake MT. The skeletal impact of cancer therapies. Br J Clin Pharmacol. 2019 Jun; 85 (6):1161-1168 Epub 2019 Feb 21
    View PubMed
  43. Cremers S, Drake MT, Ebetino FH, Bilezikian JP, Russell RGG. Pharmacology of bisphosphonates. Br J Clin Pharmacol. 2019 Jun; 85 (6):1052-1062 Epub 2019 Feb 28
    View PubMed
  44. Hillengass J, Usmani S, Rajkumar SV, Durie BGM, Mateos MV, Lonial S, Joao C, Anderson KC, Garcia-Sanz R, Riva E, Du J, van de Donk N, Berdeja JG, Terpos E, Zamagni E, Kyle RA, San Miguel J, Goldschmidt H, Giralt S, Kumar S, Raje N, Ludwig H, Ocio E, Schots R, Einsele H, Schjesvold F, Chen WM, Abildgaard N, Lipe BC, Dytfeld D, Wirk BM, Drake M, Cavo M, Lahuerta JJ, Lentzsch S. International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders. Lancet Oncol. 2019 Jun; 20 (6):e302-e312
    View PubMed
  45. Clinical manifestations, diagnosis, and treatment of osteomalacia UpToDate. 2019.
  46. Epidemiology and etiology of osteomalacia UpToDate. 2019.
  47. Sfeir JG, Drake MT, Sonawane VJ, Sinaki M. Vertebral compression fractures associated with yoga: a case series. Eur J Phys Rehabil Med. 2018 Dec; 54 (6):947-951 Epub 2018 Apr 24
    View PubMed
  48. Khosla S, Drake MT, Volkman TL, Thicke BS, Achenbach SJ, Atkinson EJ, Joyner MJ, Rosen CJ, Monroe DG, Farr JN. Sympathetic beta1-adrenergic signaling contributes to regulation of human bone metabolism. J Clin Invest. 2018 Nov 1; 128 (11):4832-4842 Epub 2018 Oct 02
    View PubMed
  49. Drake MT. Hypothyroidism in Clinical Practice. Mayo Clin Proc 2018 Sep; 93 (9):1169-1172
    View PubMed
  50. Sfeir JG, Drake MT, Atkinson EJ, Achenbach SJ, Camp JJ, Tweed AJ, McCready LK, Yu L, Adkins MC, Amin S, Khosla S. Evaluation of cross-sectional and longitudinal changes in volumetric bone mineral density in postmenopausal women using single- versus dual-energy quantitative computed tomography. Bone. 2018 Jul; 112:145-152. Epub 2018 Apr 25.
    View PubMed
  51. Drake MT, Fenske JS, Blocki FA, Zierold C, Appelman-Dijkstra N, Papapoulos S, Khosla S. Validation of a novel, rapid, high precision sclerostin assay not confounded by sclerostin fragments. Bone. 2018 Jun; 111:36-43 Epub 2018 Mar 14
    View PubMed
  52. Kumar S, Drake MT, Schleck CD, Johnson ML, Alexander JA, Katzka DA, Iyer PG. Incidence and predictors of osteoporotic fractures in patients with Barrett's oesophagus: a population-based nested case-control study. Aliment Pharmacol Ther. 2017 Dec; 46 (11-12):1094-1102 Epub 2017 Oct 05
    View PubMed
  53. Ammann EM, Drake MT, Haraldsson B, Wallace RB, Johnson KC, Desai P, Lin EM, Link BK. Incidence of hematologic malignancy and cause-specific mortality in the Women's Health Initiative randomized controlled trial of calcium and vitamin D supplementation. Cancer. 2017 Nov 1; 123 (21):4168-4177 Epub 2017 June 27
    View PubMed
  54. Drake MT, Collins MT, Hsiao EC. The Rare Bone Disease Working Group: report from the 2016 American Society for Bone and Mineral Research Annual Meeting. Bone. 2017 Sep; 102:80-84 Epub 2017 Jan 20
    View PubMed
  55. Farr JN, Xu M, Weivoda MM, Monroe DG, Fraser DG, Onken JL, Negley BA, Sfeir JG, Ogrodnik MB, Hachfeld CM, LeBrasseur NK, Drake MT, Pignolo RJ, Pirtskhalava T, Tchkonia T, Oursler MJ, Kirkland JL, Khosla S. Targeting cellular senescence prevents age-related bone loss in mice. Nat Med. 2017 Sep; 23(9):1072-1079. Epub 2017 Aug 21.
    View PubMed
  56. Tracy SI, Maurer MJ, Witzig TE, Drake MT, Ansell SM, Nowakowski GS, Thompson CA, Inwards DJ, Johnston PB, Micallef IN, Allmer C, Macon WR, Weiner GJ, Slager SL, Habermann TM, Link BK, Cerhan JR. Vitamin D insufficiency is associated with an increased risk of early clinical failure in follicular lymphoma. Blood Cancer J. 2017 Aug 25; 7 (8):e595
    View PubMed
  57. Hillengass J, Moulopoulos LA, Delorme S, Koutoulidis V, Mosebach J, Hielscher T, Drake M, Rajkumar SV, Oestergaard B, Abildgaard N, Hinge M, Plesner T, Suehara Y, Matsue K, Withofs N, Caers J, Waage A, Goldschmidt H, Dimopoulos MA, Lentzsch S, Durie B, Terpos E. Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group. Blood Cancer J. 2017 Aug 25; 7 (8):e599
    View PubMed
  58. Lapid MI, Kung S, Frye MA, Biernacka JM, Geske JR, Drake MT, Jankowski MD, Clarke BL. Association of the serotonin transporter-linked polymorphic region genotype with lower bone mineral density. Transl Psychiatry. 2017 Aug 22; 7 (8):e1213
    View PubMed
  59. Drake MT, Clarke BL, Oursler MJ, Khosla S. Cathepsin K Inhibitors for Osteoporosis: Biology, Potential Clinical Utility, and Lessons Learned. Endocr Rev. 2017 Aug 1; 38 (4):325-350
    View PubMed
  60. Clinical manifestations, diagnosis, and treatment of osteomalacia UpToDate. 2017.
  61. Drake MT, Khosla S. Hormonal and systemic regulation of sclerostin. Bone. 2017 Mar; 96:8-17 Epub 2016 Dec 10
    View PubMed
  62. Lwin ST, Fowler JA, Drake MT, Edwards JR, Lynch CC, Edwards CM. A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo. Mol Cancer. 2017 Feb 28; 16 (1):49
    View PubMed
  63. Sfeir JG, Drake MT, LaPlant BR, Maurer MJ, Link BK, Berndt TJ, Shanafelt TD, Cerhan JR, Habermann TM, Feldman AL, Witzig T. Validation of a vitamin D replacement strategy in vitamin D-insufficient patients with lymphoma or chronic lymphocytic leukemia. Blood Cancer J. 2017 Feb 3; 7 (2):e526 Epub 2017 Feb 03
    View PubMed
  64. Farr JN, Fraser DG, Wang H, Jaehn K, Ogrodnik MB, Weivoda MM, Drake MT, Tchkonia T, LeBrasseur NK, Kirkland JL, Bonewald LF, Pignolo RJ, Monroe DG, Khosla S. Identification of Senescent Cells in the Bone Microenvironment. J Bone Miner Res. 2016 Nov; 31 (11):1920-1929 Epub 2016 Oct 24
    View PubMed
  65. Elraiyah T, Ahmed AH, Wang Z, Farr JN, Murad MH, Drake MT. Predictors of teriparatide treatment failure in patients with low bone mass. Bone Rep. 2016 Jun; 4:17-22 Epub 2015 Nov 17
    View PubMed
  66. Drake MT. Commentary. Clin Chem 2016 May; 62 (5):687-8
    View PubMed
  67. Nicks KM, Fujita K, Fraser D, McGregor U, Drake MT, McGee-Lawrence ME, Westendorf JJ, Monroe DG, Khosla S. Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice. J Bone Miner Res. 2016 Mar; 31 (3):606-14 Epub 2015 Oct 13
    View PubMed
  68. Adler RA, El-Hajj Fuleihan G, Bauer DC, Camacho PM, Clarke BL, Clines GA, Compston JE, Drake MT, Edwards BJ, Favus MJ, Greenspan SL, McKinney R Jr, Pignolo RJ, Sellmeyer DE. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016 Jan; 31 (1):16-35
    View PubMed
  69. Siontis B, Kumar S, Dispenzieri A, Drake MT, Lacy MQ, Buadi F, Dingli D, Kapoor P, Gonsalves W, Gertz MA, Rajkumar SV. Positron emission tomography-computed tomography in the diagnostic evaluation of smoldering multiple myeloma: identification of patients needing therapy. Blood Cancer J. 2015 Oct 23; 5:e364
    View PubMed
  70. Shah M, Bancos I, Thompson GB, Richards ML, Kasperbauer JL, Clarke BL, Drake MT, Stan MN. Teriparatide Therapy and Reduced Postoperative Hospitalization for Postsurgical Hypoparathyroidism. JAMA Otolaryngol Head Neck Surg. 2015 Sep; 141: (9)822-7.
    View PubMed
  71. Stan MN, Haglind EG, Drake MT. Early Hypoparathyroidism Reversibility with Treatment of Riedel's Thyroiditis. Thyroid. 2015 Sep; 25: (9)1055-9.
    View PubMed
  72. Drake MT, Clarke BL, Lewiecki EM. The Pathophysiology and Treatment of Osteoporosis. Clin Ther. 2015 Aug; 37 (8):1837-50 Epub 2015 July 07
    View PubMed
  73. Roforth MM, Farr JN, Fujita K, McCready LK, Atkinson EJ, Therneau TM, Cunningham JM, Drake MT, Monroe DG, Khosla S. Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women. Bone. 2015 Jul; 76:49-57 Epub 2015 Mar 27
    View PubMed
  74. Al Bawardy BF, Simonetto DA, Drake MT. 62-year-old man with persistent postoperative nausea and vomiting. Mayo Clin Proc. 2015 Feb; 90(2):280-3.
    View PubMed
  75. Farr JN, Roforth MM, Fujita K, Nicks KM, Cunningham JM, Atkinson EJ, Therneau TM, McCready LK, Peterson JM, Drake MT, Monroe DG, Khosla S. Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing. PLoS One. 2015; 10 (9):e0138347 Epub 2015 Sept 24
    View PubMed
  76. Drake MT. unveiling skeletal fragility in patients diagnosed with MGUS: no longer a condition of undetermined significance? J Bone Miner Res. 2014 Dec; 29 (12):2529-33
    View PubMed
  77. Drake MT. The Battle for Bone Health Endocrine Today. 2014.
  78. Inwards DJ, Fishkin PA, LaPlant BR, Drake MT, Kurtin PJ, Nikcevich DA, Wender DB, Lair BS, Witzig TE. Phase I trial of rituximab, cladribine, and temsirolimus (RCT) for initial therapy of mantle cell lymphoma. Ann Oncol. 2014 Oct; 25 (10):2020-2024 Epub 2014 July 23
    View PubMed
  79. PTH in post-surgical hypoparathyroidism 84th Annual Meeting of the American Thyroid Association Program. 2014.
  80. Drake MT, Farr JN. Inhibitors of sclerostin: emerging concepts. Curr Opin Rheumatol. 2014 Jul; 26 (4):447-52
    View PubMed
  81. Farr JN, Drake MT, Amin S, Melton LJ 3rd, McCready LK, Khosla S. In vivo assessment of bone quality in postmenopausal women with type 2 diabetes. J Bone Miner Res. 2014 Apr; 29 (4):787-95
    View PubMed
  82. Fujita K, Roforth MM, Atkinson EJ, Peterson JM, Drake MT, McCready LK, Farr JN, Monroe DG, Khosla S. Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture. Osteoporos Int. 2014 Mar; 25 (3):887-95 Epub 2013 Oct 11
    View PubMed
  83. Roforth MM, Fujita K, McGregor UI, Kirmani S, McCready LK, Peterson JM, Drake MT, Monroe DG, Khosla S. Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans. Bone. 2014 Feb; 59:1-6 Epub 2013 Oct 29
    View PubMed
  84. Farr JN, Zhang W, Kumar SK, Jacques RM, Ng AC, McCready LK, Rajkumar SV, Drake MT. Altered cortical microarchitecture in patients with monoclonal gammopathy of undetermined significance. Blood. 2014 Jan 30; 123 (5):647-9 Epub 2013 Nov 13
    View PubMed
  85. Fujita K, Roforth MM, Demaray S, McGregor U, Kirmani S, McCready LK, Peterson JM, Drake MT, Monroe DG, Khosla S. Effects of estrogen on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in postmenopausal women. J Clin Endocrinol Metab. 2014 Jan; 99 (1):E81-8 Epub 2013 Dec 20
    View PubMed
  86. Drake MT. Osteoporosis and cancer. Curr Osteoporos Rep. 2013 Sep; 11 (3):163-70
    View PubMed
  87. Kennel KA, Drake MT. Vitamin D in the cancer patient. Curr Opin Support Palliat Care. 2013 Sep; 7 (3):272-7
    View PubMed
  88. Ng AC, Melton LJ 3rd, Atkinson EJ, Achenbach SJ, Holets MF, Peterson JM, Khosla S, Drake MT. Relationship of adiposity to bone volumetric density and microstructure in men and women across the adult lifespan. Bone. 2013 Jul; 55 (1):119-25 Epub 2013 Feb 18
    View PubMed
  89. Terpos E, Morgan G, Dimopoulos MA, Drake MT, Lentzsch S, Raje N, Sezer O, Garcia-Sanz R, Shimizu K, Turesson I, Reiman T, Jurczyszyn A, Merlini G, Spencer A, Leleu X, Cavo M, Munshi N, Rajkumar SV, Durie BG, Roodman GD. International Myeloma Working Group recommendations for the treatment of multiple myeloma-related bone disease. J Clin Oncol. 2013 Jun 20; 31(18):2347-57. Epub 2013 May 20.
    View PubMed
  90. Berkseth KE, Tebben PJ, Drake MT, Hefferan TE, Jewison DE, Wermers RA. Clinical spectrum of hypophosphatasia diagnosed in adults. Bone. 2013 May; 54(1):21-7. Epub 2013 Jan 22.
    View PubMed
  91. Leedahl DD, Cunningham JL, Drake MT, Mundis CB, Kung S, Frye MA, Lapid MI. Hypovitaminosis D in psychiatric inpatients: clinical correlation with depressive symptoms, cognitive impairment, and prescribing practices. Psychosomatics. 2013 May-Jun; 54(3):257-62. Epub 2012 Dec 01.
    View PubMed
  92. Mikhael JR, Dingli D, Roy V, Reeder CB, Buadi FK, Hayman SR, Dispenzieri A, Fonseca R, Sher T, Kyle RA, Lin Y, Russell SJ, Kumar S, Bergsagel PL, Zeldenrust SR, Leung N, Drake MT, Kapoor P, Ansell SM, Witzig TE, Lust JA, Dalton RJ, Gertz MA, Stewart AK, Rajkumar SV, Chanan-Khan A, Lacy MQ, Mayo Clinic. Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines 2013. Mayo Clin Proc. 2013 Apr; 88 (4):360-76
    View PubMed
  93. Lapid MI, Drake MT, Geske JR, Mundis CB, Hegard TL, Kung S, Frye MA. Hypovitaminosis D in psychogeriatric inpatients. J Nutr Health Aging. 2013 Mar; 17 (3):231-4
    View PubMed
  94. Clarke BL, Drake MT. Clinical utility of serum sclerostin measurements. Bonekey Rep. 2013; 2:361 Epub 2013 June 05
    View PubMed
  95. Drake MT, Khosla S. Male osteoporosis. Endocrinol Metab Clin North Am. 2012 Sep; 41 (3):629-41 Epub 2012 June 17
    View PubMed
  96. Kelly JL, Drake MT, Fredericksen ZS, Asmann YW, Liebow M, Shanafelt TD, Feldman AL, Ansell SM, Macon WR, Herr MM, Wang AH, Nowakowski GS, Call TG, Habermann TM, Slager SL, Witzig TE, Cerhan JR. Early life sun exposure, vitamin D-related gene variants, and risk of non-Hodgkin lymphoma. Cancer Causes Control. 2012 Jul; 23: (7)1017-29.
    View PubMed
  97. Watts NB, Adler RA, Bilezikian JP, Drake MT, Eastell R, Orwoll ES, Finkelstein JS, Endocrine Society. Osteoporosis in men: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012 Jun; 97(6):1802-22.
    View PubMed
  98. Drake MT, Murad MH, Mauck KF, Lane MA, Undavalli C, Elraiyah T, Stuart LM, Prasad C, Shahrour A, Mullan RJ, Hazem A, Erwin PJ, Montori VM. Clinical review. Risk factors for low bone mass-related fractures in men: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2012 Jun; 97 (6):1861-70 Epub 2012 Mar 30
    View PubMed
  99. Murad MH, Drake MT, Mullan RJ, Mauck KF, Stuart LM, Lane MA, Abu Elnour NO, Erwin PJ, Hazem A, Puhan MA, Li T, Montori VM. Clinical review. Comparative effectiveness of drug treatments to prevent fragility fractures: a systematic review and network meta-analysis. J Clin Endocrinol Metab. 2012 Jun; 97 (6):1871-80
    View PubMed
  100. Ng AC, Drake MT, Clarke BL, Sems SA, Atkinson EJ, Achenbach SJ, Melton LJ 3rd. Trends in subtrochanteric, diaphyseal, and distal femur fractures, 1984-2007. Osteoporos Int. 2012 Jun; 23 (6):1721-6 Epub 2011 Sept 10
    View PubMed
  101. Zhang W, Drake MT. Potential role for therapies targeting DKK1, LRP5, and serotonin in the treatment of osteoporosis. Curr Osteoporos Rep. 2012 Mar; 10 (1):93-100
    View PubMed
  102. Ng AC, Khosla S, Charatcharoenwitthaya N, Kumar SK, Achenbach SJ, Holets MF, McCready LK, Melton LJ 3rd, Kyle RA, Rajkumar SV, Drake MT. Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1alpha levels in patients with MGUS. Blood. 2011 Dec 15; 118 (25):6529-34 Epub 2011 Oct 31
    View PubMed
  103. Pardanani A, Drake MT, Finke C, Lasho TL, Rozell SA, Jimma T, Tefferi A. Vitamin D insufficiency in myeloproliferative neoplasms and myelodysplastic syndromes: clinical correlates and prognostic studies. Am J Hematol. 2011 Dec; 86(12):1013-6.
    View PubMed
  104. Fowler JA, Lwin ST, Drake MT, Edwards JR, Kyle RA, Mundy GR, Edwards CM. Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease. Blood. 2011 Nov 24; 118(22):5872-82. Epub 2011 Sep 08.
    View PubMed
  105. Drake MT, Srinivasan B, Modder UI, Ng AC, Undale AH, Roforth MM, Peterson JM, McCready LK, Riggs BL, Khosla S. Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women. Bone. 2011 Sep; 49 (3):349-55 Epub 2011 May 11
    View PubMed
  106. Shanafelt TD, Drake MT, Maurer MJ, Allmer C, Rabe KG, Slager SL, Weiner GJ, Call TG, Link BK, Zent CS, Kay NE, Hanson CA, Witzig TE, Cerhan JR. Vitamin D insufficiency and prognosis in chronic lymphocytic leukemia. Blood. 2011 Feb 3; 117 (5):1492-8 Epub 2010 Nov 03
    View PubMed
  107. Undale A, Srinivasan B, Drake M, McCready L, Atkinson E, Peterson J, Riggs BL, Amin S, Modder UI, Khosla S. Corrigendum to "Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women" [Bone 47 (2010) 83-92]. Bone. 2011; 48(3):671.
  108. Burrus TM, Drake MT, Sanderson SO, Keegan BM. A case of endocrinologic crisis in a woman with subacute blindness. Neurology. 2010 Nov 2; 75(18 Suppl 1):S65.
    View PubMed
  109. Drake MT, Srinivasan B, Modder UI, Peterson JM, McCready LK, Riggs BL, Dwyer D, Stolina M, Kostenuik P, Khosla S. Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab. 2010 Nov; 95 (11):5056-62 Epub 2010 July 14
    View PubMed
  110. Drake MT, McCready LK, Hoey KA, Atkinson EJ, Khosla S. Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women. J Clin Endocrinol Metab. 2010 Nov; 95 (11):5063-8 Epub 2010 July 07
    View PubMed
  111. Terpos E, Dimopoulos MA, Sezer O, Roodman D, Abildgaard N, Vescio R, Tosi P, Garcia-Sanz R, Davies F, Chanan-Khan A, Palumbo A, Sonneveld P, Drake MT, Harousseau JL, Anderson KC, Durie BG, International Myeloma. The use of biochemical markers of bone remodeling in multiple myeloma: a report of the International Myeloma Working Group. Leukemia. 2010 Oct; 24(10):1700-12. Epub 2010 Sep 02.
    View PubMed
  112. Drake MT, Maurer MJ, Link BK, Habermann TM, Ansell SM, Micallef IN, Kelly JL, Macon WR, Nowakowski GS, Inwards DJ, Johnston PB, Singh RJ, Allmer C, Slager SL, Weiner GJ, Witzig TE, Cerhan JR. Vitamin D insufficiency and prognosis in non-Hodgkin's lymphoma. J Clin Oncol. 2010 Sep 20; 28 (27):4191-8 Epub 2010 Aug 16
    View PubMed
  113. Kennel KA, Drake MT, Hurley DL. Vitamin D deficiency in adults: when to test and how to treat. Mayo Clin Proc. 2010 Aug; 85 (8):752-7; quiz 757-8
    View PubMed
  114. Undale A, Srinivasan B, Drake M, McCready L, Atkinson E, Peterson J, Riggs BL, Amin S, Modder UI, Khosla S. Circulating osteogenic cells: characterization and relationship to rates of bone loss in postmenopausal women. Bone. 2010 Jul; 47 (1):83-92 Epub 2010 Mar 31
    View PubMed
  115. Berenson JR, Anderson KC, Audell RA, Boccia RV, Coleman M, Dimopoulos MA, Drake MT, Fonseca R, Harousseau JL, Joshua D, Lonial S, Niesvizky R, Palumbo A, Roodman GD, San-Miguel JF, Singhal S, Weber DM, Zangari M, Wirtschafter E, Yellin O, Kyle RA. Monoclonal gammopathy of undetermined significance: a consensus statement. Br J Haematol. 2010 Jul; 150(1):28-38. Epub 2010 May 09.
    View PubMed
  116. Drake MT, Cremers SC. Bisphosphonate therapeutics in bone disease: the hard and soft data on osteoclast inhibition. Mol Interv. 2010 Jun; 10(3):141-52.
    View PubMed
  117. Drake MT, Ng AC. Vitamin D deficiency in multiple myeloma. European journal of Clinical and Medical Oncology. 2010; 2(1).
  118. Drake MT. Bone disease in multiple myeloma. Oncology (Williston Park). 2009 Dec; 23(14 Suppl 5):28-32.
    View PubMed
  119. Kennel KA, Drake MT. Adverse effects of bisphosphonates: implications for osteoporosis management. Mayo Clin Proc. 2009 Jul; 84 (7):632-7; quiz 638
    View PubMed
  120. Ng AC, Kumar SK, Rajkumar SV, Drake MT. Impact of vitamin D deficiency on the clinical presentation and prognosis of patients with newly diagnosed multiple myeloma. Am J Hematol. 2009 Jul; 84 (7):397-400
    View PubMed
  121. Lee I, Drake MT, Traub LM, Kornfeld S. Cargo-sorting signals promote polymerization of adaptor protein-1 in an Arf-1.GTP-independent manner. Arch Biochem Biophys. 2008 Nov 1; 479(1):63-8. Epub 2008 Aug 20.
    View PubMed
  122. Drake MT, Clarke BL, Khosla S. Bisphosphonates: mechanism of action and role in clinical practice. Mayo Clin Proc. 2008 Sep; 83 (9):1032-45
    View PubMed
  123. Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ. beta-arrestin-biased agonism at the beta2-adrenergic receptor. J Biol Chem. 2008 Feb 29; 283(9):5669-76. Epub 2007 Dec 17.
    View PubMed
  124. Wisler JW, DeWire SM, Whalen EJ, Violin JD, Drake MT, Ahn S, Shenoy SK, Lefkowitz RJ. A unique mechanism of beta-blocker action: Carvedilol stimulates beta-arrestin signaling. Proc Natl Acad Sci U S A. 2007 Oct 16; 104(42):16657-62. Epub 2007 Oct 9.
    View PubMed
  125. Drake MT, Shenoy SK, Lefkowitz RJ. Trafficking of G protein-coupled receptors. Circ Res. 2006 Sep 15; 99(6):570-82.
    View PubMed
  126. Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J Biol Chem. 2006 Jan 13; 281(2):1261-73. Epub 2005 Nov 09.
    View PubMed
  127. Green AD, Colon-Emeric CS, Bastian L, Drake MT, Lyles KW. Does this woman have osteoporosis? JAMA. 2004 Dec 15; 292(23):2890-900.
    View PubMed
  128. Drake MT, Traub LM. Interaction of two structurally distinct sequence types with the clathrin terminal domain beta-propeller. J Biol Chem. 2001 Aug 3; 276(31):28700-9. Epub 2001 May 29.
    View PubMed
  129. Zhu Y, Drake MT, Kornfeld S. Adaptor protein 1-dependent clathrin coat assembly on synthetic liposomes and Golgi membranes. Methods Enzymol. 2001; 329:379-87.
    View PubMed
  130. Drake MT, Zhu Y, Kornfeld S. The assembly of AP-3 adaptor complex-containing clathrin-coated vesicles on synthetic liposomes. Mol Biol Cell. 2000 Nov; 11(11):3723-36.
    View PubMed
  131. Drake MT, Downs MA, Traub LM. Epsin binds to clathrin by associating directly with the clathrin-terminal domain. Evidence for cooperative binding through two discrete sites. J Biol Chem. 2000 Mar 3; 275(9):6479-89.
    View PubMed
  132. Zhu Y, Drake MT, Kornfeld S. ADP-ribosylation factor 1 dependent clathrin-coat assembly on synthetic liposomes. Proc Natl Acad Sci U S A. 1999 Apr 27; 96(9):5013-8.
    View PubMed
  133. Iida-Klein A, Guo J, Takemura M, Drake MT, Potts JT Jr, Abou-Samra A, Bringhurst FR, Segre GV. Mutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTH-related protein receptor result in selective loss of PTH-stimulated phospholipase C activity. J Biol Chem. 1997 Mar 14; 272(11):6882-9.
    View PubMed
  134. Iida-Klein A, Guo J, Drake MT, Kronenberg HM, Abou-Samra AB, Bringhurst FR, Segre GV. Structural requirements of parathyroid hormone/parathyroid hormone-related peptide receptors for phospholipase C activation and regulation of phosphate uptake. Miner Electrolyte Metab. 1995; 21(1-3):177-9.
    View PubMed
  135. Drake MT, Baldassare JJ, McConkey CL, Gonzalez EA, Martin KJ. Parathyroid hormone increases the expression of receptors for epidermal growth factor in UMR 106-01 cells. Endocrinology. 1994 Apr; 134(4):1733-7.
    View PubMed
PST-20224813