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Pietro Di Santo, M.D., Ph.D.

  1. Critical Care Specialist
  2. Interventional Cardiologist
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Publications

  1. Motazedian P, Di Santo P, Prosperi-Porta G, Nelson D, Morgan B, Ratelle C, Feagan H, Koopman Z, Jung R, Mathieu ME, Knoll W, Parlow S, Abdel-Razek O, Mathew R, Wells GA, Chiu MH, Ballantyne B, Hibbert B, Ramirez FD. Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design. Am Heart J. 2026 May; 295:107358 Epub 2026 Jan 25
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  2. Jung RG, Gupta A, Stotts C, McNeely C, Mihic A, Hanycz S, Kamra M, Shore I, Hakimjavadi R, Parlow S, Shorr R, Motazedian P, Prosperi-Porta G, Mathew R, Di Santo P, Klompas M, Fernando SM, Rochwerg B, Hibbert B. Prognostic factors associated with mortality in septic shock: a systematic review and meta-analysis. Lancet Respir Med. 2026 Mar; 14 (3):225-232 Epub 2026 Jan 28
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  3. Parlow S, Jung RG, Almoosawy SA, Lepage-Ratte MF, Durr M, Mathieu ME, Di Santo P, Motazedian P, Sterling LH, Abdel-Razek O, Fan E, Thiele H, Price S, van Diepen S, Visintini S, Basir MB, Kapur NK, Hibbert B, Tran A, Moller JE, Rochwerg B, Mathew R, Fernando SM. Prognostic Factors Among Patients Receiving Microaxial Flow Pump for Acute Myocardial Infarction-Related Cardiogenic Shock: A Systematic Review and Meta-Analysis. Crit Care Med. 2026 Mar 1; 54 (3):584-593 Epub 2026 Jan 08
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  4. Ten Berg S, Bogerd M, Peters EJ, Ameloot K, Grand J, Russo JJ, Jentzer JC, Santo PD, Mathew R, Hibbert B, Kjaergaard J, Meyer MAS, Skrifvars MB, Roberts BW, Levy B, Merdji H, Malekzadeh A, Lagrand WK, Engstrom AE, Vlaar APJ, Otterspoor LC, Henriques JPS. Mean Arterial Pressure and Mortality in Infarction-Related Cardiogenic Shock with and without Cardiac Arrest: A Meta-Analysis. J Card Fail. 2026 Jan 2 Epub 2026 Jan 02
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  5. Boudreau R, Chih S, Le May M, Di Santo P, Mathew R, Boodhwani M, Toeg H, Wilson B, Chong AY, So DYF. Balancing Costs and Benefits: A Less DanGerous Protocol for Myocardial Infarction Complicated by Cardiogenic Shock. Can J Cardiol. 2025 Oct; 41(10):2064-2068. Epub 2025 Jun 10.
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  6. Mathew R, Di Santo P, Hibbert B. The Training Program as a Catalyst for Clinical Trials in Cardiac Critical Care: The DOREMI Experience Journal of Cardiac Failure - Intersections. 2025; 1(1):66-71.
  7. Motazedian P, Prosperi-Porta G, Mathieu ME, Beauregard N, Knoll W, Quinn N, Parlow S, Di Santo P, Abdel-Razek O, Jung R, Kolobaric N, Barbour W, Nelson D, Simard T, Jentzer JC, Mathew R, Wells GA, Ramirez FD, Hibbert B. The lack of evidence-based management in electrical storm: a scoping review. BMC Cardiovasc Disord 2025 Jul 30; 25 (1):556 Epub 2025 July 30
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  8. Motazedian P, Prosperi-Porta G, Hibbert B, Jalal H, Labinaz M, Burwash IG, Abdel-Razek O, Di Santo P, Simard T, Wells G, Coyle D. Cost-effectiveness of population screening for aortic stenosis. Eur Heart J Qual Care Clin Outcomes. 2025 Jun 23; 11 (4):378-387
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  9. Theriault-Lauzier P, Perrin N, Sarshoghi A, Ly S, Knafo M, Grandchamp A, Rong YX, Lessard MG, Corbin D, Taji B, Tastet O, Chong AY, Froeschl M, Dick A, Labinaz M, Glover C, Le May M, Ahmed Z, Abdel-Razek O, Di Santo P, Messika-Zeitoun D, Tison GH, Russo J, Marquis-Gravel G, Tanguay JF, Gallo R, Ly QH, Asgar A, Doucet S, Gosselin G, Gregorie J, Ibrahim R, L'allier PL, Nosair M, So DYF, Avram R. Clinical Deployment of Real-Time Left Ventricular Ejection Fraction Estimation from Coronary Angiography New England Journal of Medicine. 2025; 2(5).
  10. Boudreau R, Le May M, Malhotra N, Clifford C, Barry Q, Knoll W, Laverdure M, Glover T, Helmeczi W, Boroujeni SF, Labinaz M, Dick A, Glover C, Froeschl M, Ahmed Z, Abdel-Razek O, Di Santo P, Chih S, Mathew R, Boodhwani M, Toeg H, Wilson B, Chong AY, So DYF. Evaluating Volume and Resource Needs for Implementing an ST-Elevation Myocardial Infarction Shock Protocol. Can J Cardiol. 2025 Apr; 41(4):784-788. Epub 2025 Feb 06.
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  11. Prosperi-Porta G, Dryden A, Nicholson D, Hynes M, Chan V, Jung RG, Di Santo P, Simard T, Labinaz M, Hibbert B, Abdel-Razek O. Concomitant Transcatheter Edge-to-Edge Repair and Left Atrial Appendage Occlusion. J Clin Med. 2025 Mar 26; 14 (7)
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  12. Parlow S, Jung RG, Di Santo P, Joseph J, Skanes S, Abdel-Razek O, Prosperi-Porta G, Motazedian P, Froeschl M, Labinaz M, Mathew R, Ramirez FD, Simard T, Hibbert B. Utility of Noninvasive Testing Before Invasive Coronary Angiography in the Assessment for Revascularization. Mayo Clin Proc Innov Qual Outcomes. 2025 Feb; 9 (1):100589 Epub 2025 Jan 02
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  13. Al-Abcha A, Di Santo P, Rihal CS, Simard T, Hibbert B, Alkhouli M. Outcomes of Combined Left Atrial Appendage Occlusion and Transcatheter Mitral Edge-to-Edge Repair: The WATCH-TEER Study. JACC Adv. 2025 Feb; 4 (2):101541 Epub 2025 Jan 08
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  14. Di Santo P, Abdel-Razek O, Prosperi-Porta G, Motazedian P, Theriault-Lauzier P, Alhassani S, Sterling LH, Parlow S, Mathieu ME, Jung RG, Morgan B, Coyle D, Fergusson DA, Kyeremanteng K, Mathew R, Labinaz M, Froeschl M, Hibbert R, Simard T, Bird JG, Wells GA, Hibbert B. Point-of-Care Ultrasound for the Detection of Vascular Access Site Complications-The ULTRASITCOM Study. J Soc Cardiovasc Angiogr Interv. 2025 Feb; 4 (2):102516 Epub 2025 Feb 18
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  15. Jung RG, Stotts C, Gupta A, Prosperi-Porta G, Dhaliwal S, Motazedian P, Abdel-Razek O, Di Santo P, Parlow S, Belley-Cote E, Tran A, van Diepen S, Harel-Sterling L, Goyal V, Lepage-Ratte MF, Mathew R, Jentzer JC, Price S, Naidu SS, Basir MB, Kapur NK, Thiele H, Ramirez FD, Wells G, Rochwerg B, Fernando SM, Hibbert B. Prognostic Factors Associated with Mortality in Cardiogenic Shock - A Systematic Review and Meta-Analysis. NEJM Evid. 2024 Nov; 3 (11):EVIDoa2300323 Epub 2024 Oct 22
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  16. Motazedian P, Beauregard N, Letourneau I, Olaye I, Syed S, Lam E, Di Santo P, Mathew R, Clark EG, Sood MM, Lalu MM, Hibbert B, Bugeja A. Central Venous Oxygen Saturation for Estimating Mixed Venous Oxygen Saturation and Cardiac Index in the ICU: A Systematic Review and Meta-Analysis. Crit Care Med. 2024 Nov 1; 52 (11):e568-e577 Epub 2024 Sept 11
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  17. Motazedian P, Quinn N, Wells GA, Beauregard N, Lam E, Mathieu ME, Knoll W, Prosperi-Porta G, Ly V, Parlow S, Di Santo P, Abdel-Razek O, Jung R, Simard T, Jentzer JC, Mathew R, Ramirez FD, Hibbert B. Efficacy of stellate ganglion block in treatment of electrical storm: a systematic review and meta-analysis. Sci Rep. 2024 Oct 21; 14(1):24719.
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  18. Parlow S, Fernando SM, Pugliese M, Qureshi D, Talarico R, Sterling LH, van Diepen S, Herridge MS, Price S, Brodie D, Fan E, McIsaac DI, Di Santo P, Jung RG, Slutsky AS, Scales DC, Combes A, Hibbert B, Thiele H, Tanuseputro P, Mathew R, LOTUS-ICU Research Group. Resource Utilization and Costs Associated With Cardiogenic Shock Complicating Myocardial Infarction: A Population-Based Cohort Study. JACC Adv. 2024 Aug; 3 (8):101047 Epub 2024 July 02
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  19. Fernando SM, Qureshi D, Talarico R, Vigod SN, McIsaac DI, Sterling LH, van Diepen S, Price S, Di Santo P, Kyeremanteng K, Fan E, Needham DM, Brodie D, Bienvenu OJ, Combes A, Slutsky AS, Scales DC, Herridge MS, Thiele H, Hibbert B, Tanuseputro P, Mathew R. Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study. Intensive Care Med. 2024 Jun; 50(6):901-912. Epub 2024 May 02.
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  20. Abdel-Razek O, Jung RG, Di Santo P, Mathew R, Hibbert B. Impact of hypoxic hepatitis in cardiogenic shock: a substudy of the DOREMI trial. Eur Heart J Open. 2024 May; 4 (3):oeae024 Epub 2024 Mar 22
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  21. Stotts C, Jung RG, Prosperi-Porta G, Di Santo P, Abdel-Razek O, Parlow S, Ramirez FD, Simard T, Labinaz M, Morgan B, Robinson L, Mathew R, Hibbert B. Management and Outcomes of Type I and Type II Myocardial Infarction in Cardiogenic Shock. CJC Open. 2024 Feb; 6 (2Part A):122-132 Epub 2023 Oct 16
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  22. Joseph J, Scerbo J, Di Santo P, Hibbert B. Percutaneous repair of a sinotubular junction aortic pseudoaneurysm with an atrial septal defect occluder: a case report. Eur Heart J Case Rep. 2023 Dec; 7(12):ytad597. Epub 2023 Nov 28.
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  23. Motazedian P, Marbach JA, Prosperi-Porta G, Parlow S, Di Santo P, Abdel-Razek O, Jung R, Bradford WB, Tsang M, Hyon M, Pacifici S, Mohanty S, Ramirez FD, Huggins GS, Simard T, Hon S, Hibbert B. Diagnostic accuracy of point-of-care ultrasound with artificial intelligence-assisted assessment of left ventricular ejection fraction. NPJ Digit Med. 2023 Oct 28; 6 (1):201
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  24. Simard T, Jung R, Di Santo P, Sarathy K, Majeed K, Motazedian P, Short S, Dhaliwal S, Labinaz A, Sarma D, Ramirez FD, Froeschl M, Labinaz M, Holmes DR, Alkhouli M, Hibbert B. Evaluation of a Rabbit Model of Vascular Stent Healing: Application of Optical Coherence Tomography. J Cardiovasc Transl Res. 2023 Oct; 16 (5):1194-1204 Epub 2023 May 25
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  25. Sterling LH, Fernando SM, Talarico R, Qureshi D, van Diepen S, Herridge MS, Price S, Brodie D, Fan E, Di Santo P, Jung RG, Parlow S, Basir MB, Scales DC, Combes A, Mathew R, Thiele H, Tanuseputro P, Hibbert B. Long-Term Outcomes of Cardiogenic Shock Complicating Myocardial Infarction. J Am Coll Cardiol. 2023 Sep 5; 82 (10):985-995
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  26. Abdel-Razek O, Di Santo P, Jung RG, Parlow S, Motazedian P, Prosperi-Porta G, Visintini S, Marbach JA, Ramirez FD, Simard T, Labinaz M, Mathew R, Hibbert B. Efficacy of Milrinone and Dobutamine in Cardiogenic Shock: An Updated Systematic Review and Meta-Analysis. Crit Care Explor. 2023 Sep; 5 (9):e0962 Epub 2023 Aug 28
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  27. Parlow S, Santo PD, Sterling LH, Goodliffe L, Motazedian P, Prosperi-Porta G, Morgan B, Koopman Z, Jung RG, Lepage-Ratte MF, Robinson L, Feagan H, Simard T, Wells GA, Kyeremanteng K, Ainsworth C, Amin F, Marbach JA, Fernando SM, Labinaz M, Belley-Cote EP, Hibbert B, Mathew R. Inotrope versus placebo therapy in cardiogenic shock: Rationale and study design of the CAPITAL DOREMI2 trial. Am Heart J. 2023 Aug; 262:83-89. Epub 2023 Apr 23.
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  28. Di Santo P, Dehghan K, Mao B, Jung RG, Fadare D, Paydar J, Parlow S, Motazedian P, Prosperi-Porta G, Abdel-Razek O, Joseph J, Goh CY, Chung K, Mulloy A, Ramirez FD, Simard T, Hibbert B, Mathew R, Russo JJ. Milrinone vs Dobutamine for the Management of Cardiogenic Shock: Implications of Renal Function and Injury. JACC Adv. 2023 Jul; 2 (5):100393 Epub 2023 July 05
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  29. Di Santo P, Abdel-Razek O, Jung R, Parlow S, Poulin A, Bernick J, Morgan B, Robinson L, Feagan H, Wade J, Goh CY, Singh K, Froeschl M, Labinaz M, Fergusson DA, Coyle D, Kyeremanteng K, Abunassar J, Wells GA, Simard T, Hibbert B. Rationale and Design of the Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion Trial (CAPITAL-RAPTOR). BMJ Open. 2023 May 12; 13 (5):e070720
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  30. Di Santo P, Boland PW, Abdel-Razek O, Simard T, Jung RG, Parlow S, Motazedian P, Joseph J, Theriault-Lauzier P, Alomar A, Hillani A, Alhassani S, Ali MB, Kyeremanteng K, Coyle D, Fergusson D, Wells GA, Froeschl M, Labinaz M, Russo JJ, Hibbert B. Association Between the Access Site for Coronary Angiography and Catheter-induced Coronary Artery Dissection. J Soc Cardiovasc Angiogr Interv. 2023 May-Jun; 2 (3):100606 Epub 2023 Mar 04
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  31. Jung RG, Di Santo P, Mathew R, Simard T, Parlow S, Weng W, Abdel-Razek O, Malhotra N, Cheung M, Hutson JH, Marbach JA, Motazedian P, Thibert MJ, Fernando SM, Nery PB, Nair GM, Russo JJ, Hibbert B, Ramirez FD. Arrhythmic Events and Mortality in Patients With Cardiogenic Shock on Inotropic Support: Results of the DOREMI Randomized Trial. Can J Cardiol. 2023 Apr; 39 (4):394-402 Epub 2022 Sept 20
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  32. Willner N, Prosperi-Porta G, Lau L, Nam Fu AY, Boczar K, Poulin A, Di Santo P, Unni RR, Visintini S, Ronksley PE, Chan KL, Beauchesne L, Burwash IG, Messika-Zeitoun D. Aortic Stenosis Progression: A Systematic Review and Meta-Analysis. JACC Cardiovasc Imaging. 2023 Mar; 16 (3):314-328 Epub 2022 Dec 14
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  33. Simard T, Jung R, Di Santo P, Labinaz A, Short S, Motazedian P, Dhaliwal S, Sarma D, Rasheed A, Ramirez FD, Froeschl M, Labinaz M, Holmes DR, Alkhouli M, Hibbert B. Dipyridamole and vascular healing following stent implantation. Front Cardiovasc Med. 2023; 10:1130304 Epub 2023 Sept 08
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  34. Fernando SM, Mathew R, Sadeghirad B, Rochwerg B, Hibbert B, Munshi L, Fan E, Brodie D, Di Santo P, Tran A, McLeod SL, Vaillancourt C, Cheskes S, Feguson ND, Scales DC, Lin S, Sandroni C, Soar J, Dorian P, Perkins GC, Nolan JP. Epinephrine in Out-of-Hospital Cardiac Arrest: A systematic renew and network Meta-Analysis Chest. 2023.
  35. Fernando SM, Mathew R, Sadeghirad B, Brodie D, Belley-Cote EP, Thiele H, van Diepen S, Fan E, Di Santo P, Simard T, Russo JJ, Tran A, Levy B, Combes A, Hibbert B, Rochwerg B. Inotropes, vasopressors, and mechanical circulatory support for treatment of cardiogenic shock complicating myocardial infarction: a systematic review and network meta-analysis. Can J Anaesth. 2022 Dec; 69 (12):1537-1553 Epub 2022 Oct 04
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  36. Parlow S, Di Santo P, Jung RG, Fam N, Czarnecki A, Horlick E, Abdel-Razek O, Chan V, Hynes M, Nicholson D, Dryden A, Fernando SM, Wells GA, Bernick J, Labinaz M, Mathew R, Simard T, Hibbert B. Transcatheter mitral valve repair for inotrope dependent cardiogenic shock - Design and rationale of the CAPITAL MINOS trial. Am Heart J. 2022 Dec; 254:81-87 Epub 2022 Aug 21
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  37. Gillmore T, Jung RG, Moreland R, Di Santo P, Stotts C, Makwana D, Abdel-Razek O, Ahmed Z, Chung K, Parlow S, Simard T, Froeschl M, Labinaz M, Hibbert B. Impact of intracoronary assessments on revascularization decisions: A contemporary evaluation. Catheter Cardiovasc Interv. 2022 Nov; 100 (6):955-963 Epub 2022 Oct 19
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  38. Prosperi-Porta G, Motazedian P, Di Santo P, Jung RG, Parlow S, Abdel-Razek O, Simard T, Hutson J, Malhotra N, Fu A, Ramirez FD, Froeschl M, Mathew R, Hibbert B, CAPITAL DOREMI investigators. No sex-based difference in cardiogenic shock: A post-hoc analysis of the DOREMI trial. J Cardiol. 2022 Oct; 80 (4):358-364 Epub 2022 June 17
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  39. Jung RG, Duchez AC, Simard T, Dhaliwal S, Gillmore T, Di Santo P, Labinaz A, Ramirez FD, Rasheed A, Robichaud S, Ouimet M, Short S, Clifford C, Xiao F, Lordkipanidze M, Burger D, Gadde S, Rayner KJ, Hibbert B. Plasminogen Activator Inhibitor-1-Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype. JACC Basic Transl Sci. 2022 Oct; 7 (10):985-997 Epub 2022 Sept 21
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  40. Tritschler T, Patel A, Kraaijpoel N, Bhatt DL, De Luca G, Di Santo P, Feres F, Costa RA, Hibbert B, Isshiki T, Le Gal G, Castellucci LA. Case-fatality rate of major bleeding events in patients on dual antiplatelet therapy after percutaneous coronary intervention: A systematic review and meta-analysis. Res Pract Thromb Haemost. 2022 Oct; 6 (7):e12834 Epub 2022 Nov 04
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  41. Jung RG, Abdel-Razek O, Di Santo P, Gillmore T, Stotts C, Makwana D, Soriano J, Moreland R, Verreault-Julien L, Goh CY, Parlow S, Sypkes C, Ramirez DF, Sadek M, Chan V, Toeg H, Simard T, Froeschl MPV, Labinaz M, Hibbert B. Impact of atrial fibrillation on the risk of major adverse cardiac events following coronary revascularisation. Open Heart. 2022 Sep; 9 (2)
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  42. Marbach JA, Faugno AJ, Pacifici S, Chweich H, Marbach JK, Rabinowitz JB, Thayer KL, Di Santo P, Kapur NK. Strategies to reduce limb ischemia in peripheral venoarterial extracorporeal membrane oxygenation: A systematic review and Meta-analysis. Int J Cardiol. 2022 Aug 15; 361:77-84 Epub 2022 May 09
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  43. Parlow S, Weng W, Di Santo P, Jung RG, Lepage-Ratte MF, Motazedian P, Prosperi-Porta G, Abdel-Razek O, Simard T, Chan V, Labinaz M, Froeschl M, Mathew R, Hibbert B, CAPITAL DOREMI Investigators. Significant Valvular Dysfunction and Outcomes in Cardiogenic Shock: Insights From the Randomized DOREMI Trial. Can J Cardiol. 2022 Aug; 38 (8):1211-1219 Epub 2022 Apr 14
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  44. Jung RG, Simard T, Di Santo P, Hibbert B. Transcatheter edge-to-edge repair in patients with mitral regurgitation and cardiogenic shock: a new therapeutic target. Curr Opin Crit Care. 2022 Aug 1; 28 (4):426-433
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  45. Abdel-Razek O, Jung Y, Jung R, Skanes S, Dhaliwal S, Stotts C, Di Santo P, Goh CY, Verreault-Julien L, Visintini S, Bradley J, Simard T, Ramirez FD, Russo JJ, Froeschl M, Labinaz M, Hibbert B. Safety of same-day discharge in patients with left main percutaneous intervention. Coron Artery Dis. 2022 Aug 1; 33 (5):415-418 Epub 2022 Apr 27
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  46. Parlow S, Lepage-Ratte MF, Jung RG, Fernando SM, Visintini S, Sterling LH, Di Santo P, Simard T, Russo JJ, Labinaz M, Hibbert B, Nolan JP, Rochwerg B, Mathew R. Inhaled anaesthesia compared with conventional sedation in post cardiac arrest patients undergoing temperature control: A systematic review and meta-analysis. Resuscitation. 2022 Jul; 176:74-79 Epub 2022 May 27
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  47. Mathew R, Fernando SM, Hu K, Parlow S, Di Santo P, Brodie D, Hibbert B. Optimal Perfusion Targets in Cardiogenic Shock JACC Adv. 2022; 1(2):1-14.
  48. Goh CY, Parlow S, Di Santo P, Simard T, Jung R, Ahmed Z, Verreault-Julien L, Kuhar P, Chan V, Al-Atassi T, Toeg H, Bernick J, Wells GA, Ruel M, Hibbert B. Utility of a smartphone application in assessing palmar circulation prior to radial artery harvesting for coronary artery bypass grafting: rationale and design of the randomised CAPITAL iRADIAL-CABG trial. BMJ Open. 2022 Apr 08; 12(4):e055580.
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  49. Marbach JA, Di Santo P, Kapur NK, Thayer KL, Simard T, Jung RG, Parlow S, Abdel-Razek O, Fernando SM, Labinaz M, Froeschl M, Mathew R, Hibbert B. Lactate Clearance as a Surrogate for Mortality in Cardiogenic Shock: Insights From the DOREMI Trial. J Am Heart Assoc. 2022 Mar 15; 11 (6):e023322 Epub 2022 Mar 09
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  50. Verreault-Julien L, Bhatt DL, Jung RG, Di Santo P, Simard T, Avram R, Hibbert B. Predictors of angina resolution after percutaneous coronary intervention in stable coronary artery disease. Coron Artery Dis. 2022 Mar 1; 33 (2):98-104
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  51. Parlow S, Cheung M, Verreault-Julien L, Wu KY, Berardi P, Nair V, Di Santo P, Jung RG, Mathew R, Hibbert B. An Unusual Case of Obstructive Shock. JACC Case Rep. 2021 Dec 15; 3 (18):1913-1917
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  52. Simard T, Jung RG, Di Santo P, Harnett DT, Abdel-Razek O, Ramirez FD, Motazedian P, Parlow S, Labinaz A, Moreland R, Marbach J, Poulin A, Levi A, Majeed K, Boland P, Couture E, Sarathy K, Promislow S, Russo JJ, Chong AY, So D, Froeschl M, Dick A, Labinaz M, Le May M, Holmes DR Jr, Hibbert B. Modifiable Risk Factors and Residual Risk Following Coronary Revascularization: Insights From a Regionalized Dedicated Follow-Up Clinic. Mayo Clin Proc Innov Qual Outcomes. 2021 Dec; 5 (6):1138-1152 Epub 2021 Dec 04
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  53. Jung RG, Di Santo P, Mathew R, Abdel-Razek O, Parlow S, Simard T, Marbach JA, Gillmore T, Mao B, Bernick J, Theriault-Lauzier P, Fu A, Lau L, Motazedian P, Russo JJ, Labinaz M, Hibbert B. Implications of Myocardial Infarction on Management and Outcome in Cardiogenic Shock. J Am Heart Assoc. 2021 Nov 2; 10 (21):e021570 Epub 2021 Oct 29
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  54. Jung RG, Stotts C, Makwana D, Motazedian P, Di Santo P, Goh CY, Verreault-Julien L, Simard T, Ramirez FD, Hibbert B. Methodological Rigor in Preclinical Cardiovascular Research: Contemporary Performance of AHA Scientific Publications. Circ Res 2021 Oct 15; 129 (9):887-889 Epub 2021 Sept 15
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  55. Parlow S, Di Santo P, Mathew R, Jung RG, Simard T, Gillmore T, Mao B, Abdel-Razek O, Ramirez FD, Marbach JA, Dick A, Glover C, Russo JJ, Froeschl M, Labinaz M, Fernando SM, Hibbert B, CAPITAL DOREMI investigators. The association between mean arterial pressure and outcomes in patients with cardiogenic shock: insights from the DOREMI trial. Eur Heart J Acute Cardiovasc Care. 2021 Oct 01; 10(7):712-720.
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  56. Fernando SM, Di Santo P, Sadeghirad B, Lascarrou JB, Rochwerg B, Mathew R, Sekhon MS, Munshi L, Fan E, Brodie D, Rowan KM, Hough CL, McLeod SL, Vaillancourt C, Cheskes S, Ferguson ND, Scales DC, Sandroni C, Nolan JP, Hibbert B. Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets. Intensive Care Med 2021 Oct; 47 (10):1078-1088 Epub 2021 Aug 13
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  57. Di Santo P, Mathew R, Jung RG, Simard T, Skanes S, Mao B, Ramirez FD, Marbach JA, Abdel-Razek O, Motazedian P, Parlow S, Boczar KE, D'Egidio G, Hawken S, Bernick J, Wells GA, Dick A, So DY, Glover C, Russo JJ, McGuinty C, Hibbert B, CAPITAL DOREMI investigators. Impact of baseline beta-blocker use on inotrope response and clinical outcomes in cardiogenic shock: a subgroup analysis of the DOREMI trial. Crit Care. 2021 Aug 10; 25 (1):289
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  58. Mathew R, Di Santo P, Jung RG, Marbach JA, Hutson J, Simard T, Ramirez FD, Harnett DT, Merdad A, Almufleh A, Weng W, Abdel-Razek O, Fernando SM, Kyeremanteng K, Bernick J, Wells GA, Chan V, Froeschl M, Labinaz M, Le May MR, Russo JJ, Hibbert B. Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. N Engl J Med. 2021 Aug 05; 385(6):516-525.
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  59. Sarathy K, Jung RG, Simard T, Parlow S, Di Santo P, Moreland R, Jung Y, Abdel-Razek O, Boland P, Russo JJ, Chong AY, So D, Froeschl M, Dick A, Glover C, Labinaz M, Le May M, Hibbert B. Physician prediction of 1-year mortality in the cardiac catheterization laboratory: comparison to a validated risk score. Coron Artery Dis. 2021 Aug 1; 32 (5):403-410
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  60. Marbach JA, Wells G, Santo PD, So D, Chong AY, Russo J, Labinaz M, Dick A, Froeschl M, Glover C, Hibbert B, Marquis JF, MacDougall A, Kass M, Paddock V, Quraishi AUR, Chandrasekhar J, Ghosh N, Bernick J, Le May M. Acute kidney injury after radial or femoral artery access in ST-segment elevation myocardial infarction: AKI-SAFARI. Am Heart J. 2021 Apr; 234:12-22 Epub 2021 Jan 07
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  61. Simard T, Motazedian P, Dhaliwal S, Di Santo P, Jung RG, Ramirez FD, Labinaz A, Short S, Parlow S, Joseph J, Rasheed A, Rockley M, Marbach J, Domecq MC, Russo JJ, Chong AY, Beanlands RS, Hibbert B. Revisiting the Evidence for Dipyridamole in Reducing Restenosis: A Systematic Review and Meta-analysis. J Cardiovasc Pharmacol. 2021 Apr 1; 77 (4):450-457
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  62. Di Santo P, Simard T, Wells GA, Jung RG, Ramirez FD, Boland P, Marbach JA, Parlow S, Kyeremanteng K, Coyle D, Fergusson D, Russo JJ, Chong AY, Froeschl M, So DY, Dick A, Glover C, Labinaz M, Hibbert B, Le May M. Transradial Versus Transfemoral Access for Percutaneous Coronary Intervention in ST-Segment-Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis. Circ Cardiovasc Interv. 2021 Mar; 14 (3):e009994 Epub 2021 Mar 09
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  63. Jung RG, Di Santo P, Clifford C, Prosperi-Porta G, Skanes S, Hung A, Parlow S, Visintini S, Ramirez FD, Simard T, Hibbert B. Methodological quality of COVID-19 clinical research. Nat Commun. 2021 Feb 11; 12 (1):943
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  64. Jung RG, Simard T, Kovach C, Flint K, Don C, Di Santo P, Adamo M, Branca L, Valentini F, Benito-Gonzalez T, Fernandez-Vazquez F, Estevez-Loureiro R, Berardini A, Conti N, Rapezzi C, Biagini E, Parlow S, Shorr R, Levi A, Manovel A, Cardenal-Piris R, Diaz Fernandez J, Shuvy M, Haberman D, Sala A, Alkhouli MA, Marini C, Bargagna M, Schiavi D, Denti P, Markovic S, Buzzatti N, Chan V, Hynes M, Mesana T, Labinaz M, Pappalardo F, Taramasso M, Hibbert B. Transcatheter Mitral Valve Repair in Cardiogenic Shock and Mitral Regurgitation: A Patient-Level, Multicenter Analysis. JACC Cardiovasc Interv. 2021 Jan 11; 14 (1):1-11 Epub 2020 Oct 14
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  65. Simard T, Jung RG, Di Santo P, Ramirez FD, Labinaz A, Gaudet C, Motazedian P, Parlow S, Joseph J, Moreland R, Marbach J, Boland P, Promislow S, Russo JJ, Chong AY, So D, Froeschl M, Le May M, Hibbert B. Performance of Plasma Adenosine as a Biomarker for Predicting Cardiovascular Risk. Clin Transl Sci. 2021 Jan; 14 (1):354-361 Epub 2020 Dec 02
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  66. Fernando SM, Qureshi D, Tanuseputro P, Talarico R, Hibbert B, Mathew R, Rochwerg B, Belley-Cote EP, Fan E, Combes A, Brodie D, Schmidt M, Simard T, Di Santo P, Kyeremanteng K. Long-term mortality and costs following use of Impella(R) for mechanical circulatory support: a population-based cohort study. Can J Anaesth. 2020 Dec; 67 (12):1728-1737 Epub 2020 July 15
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  67. Marbach JA, Almufleh A, Di Santo P, Simard T, Jung R, Diemer G, West FM, Millington SJ, Mathew R, Le May MR, Hibbert B. A Shifting Paradigm: The Role of Focused Cardiac Ultrasound in Bedside Patient Assessment. Chest. 2020 Nov; 158 (5):2107-2118 Epub 2020 July 21
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  68. Simard T, Thangarasa T, Di Santo P, Labinaz A, Hibbert B. The balloon impasse sign in percutaneous transvenous mitral valvuloplasty. Oxf Med Case Reports. 2020 Aug; 2020 (8):omaa062 Epub 2020 Aug 10
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  69. Jung RG, Simard T, Di Santo P, Dhaliwal S, Sypkes C, Duchez AC, Moreland R, Taylor K, Parlow S, Visintini S, Labinaz A, Marbach J, Sarathy K, Bernick J, Joseph J, Boland P, Abdel-Razek O, Harnett DT, Ramirez FD, Hibbert B. Evaluation of plasminogen activator inhibitor-1 as a biomarker of unplanned revascularization and major adverse cardiac events in coronary angiography and percutaneous coronary intervention. Thromb Res. 2020 Jul; 191:125-133 Epub 2020 Apr 24
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  70. Kansal V, Simard T, Di Santo P, Chong AY, So D, Hossain A, Small G, Chow BJW, Hibbert B. Impact of trainee involvement on patient radiation exposure and contrast volumes during invasive cardiac procedures. Clin Invest Med. 2020 Apr 5; 43 (1):E18-E21 Epub 2020 Apr 05
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  71. Fernando SM, Mathew R, Hibbert B, Rochwerg B, Munshi L, Walkey AJ, Moller MH, Simard T, Di Santo P, Ramirez FD, Tanuseputro P, Kyeremanteng K. New-onset atrial fibrillation and associated outcomes and resource use among critically ill adults-a multicenter retrospective cohort study. Crit Care. 2020 Jan 13; 24 (1):15
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  72. Simard T, Motazedian P, Majeed K, Sarathy K, Jung RG, Feder J, Ramirez FD, Di Santo P, Marbach J, Dhaliwal S, Short S, Labinaz A, Schultz C, Russo JJ, So D, Chong AY, Le May M, Hibbert B. Contrast-free optical coherence tomography:Systematic evaluation of non-contrast media for intravascular assessment. PLoS One. 2020; 15 (8):e0237588 Epub 2020 Aug 20
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  73. Perry-Nguyen D, Jung RG, Labinaz A, Duchez AC, Dewidar O, Simard T, Karunakaran D, Majeed K, Sarathy K, Li R, Ramirez FD, Di Santo P, Rochman R, So D, Foin N, Hibbert B. Evaluation of an in vitro coronary stent thrombosis model for preclinical assessment. Platelets. 2020; 31 (2):167-173 Epub 2019 Apr 11
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  74. Ramirez FD, Jung RG, Motazedian P, Perry-Nguyen D, Di Santo P, MacDonald Z, Clancy AA, Labinaz A, Promislow S, Simard T, Provencher S, Bonnet S, Graham ID, Wells GA, Hibbert B. Journal Initiatives to Enhance Preclinical Research: Analyses of Stroke, Nature Medicine, Science Translational Medicine. Stroke. 2020 Jan; 51 (1):291-299 Epub 2019 Nov 13
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  75. Jung RG, Sarathy K, Di Santo P, Parlow S, Abdel-Razek O, Boland P, Simard T, Hibbert B. Physician prediction of mortality outcomes in the cardiac cath lab: comparisons to a validated risk score Coronary Artery Disease. 2020.
  76. Jung RG, Simard T, Di Santo P, Labinaz A, Moreland R, Duchez AC, Majeed K, Motazedian P, Rochman R, Jung Y, Hibbert B. Performance of plasminogen activator inhibitor-1 as a biomarker in patients undergoing coronary angiography: Analytical and biological considerations. Diab Vasc Dis Res. 2019 Sep; 16 (5):478-482 Epub 2019 May 08
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  77. Marbach JA, Almufleh A, Di Santo P, Jung R, Simard T, McInnes M, Salameh JP, McGrath TA, Millington SJ, Diemer G, West FM, Domecq MC, Hibbert B. Comparative Accuracy of Focused Cardiac Ultrasonography and Clinical Examination for Left Ventricular Dysfunction and Valvular Heart Disease: A Systematic Review and Meta-analysis. Ann Intern Med. 2019 Aug 20; 171 (4):264-272 Epub 2019 Aug 06
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  78. Simard T, Jung R, Labinaz A, Faraz MA, Ramirez FD, Di Santo P, Perry-Nguyen D, Pitcher I, Motazedian P, Gaudet C, Rochman R, Marbach J, Boland P, Sarathy K, Alghofaili S, Russo JJ, Couture E, Promislow S, Beanlands RS, Hibbert B. Evaluation of Plasma Adenosine as a Marker of Cardiovascular Risk: Analytical and Biological Considerations. J Am Heart Assoc. 2019 Aug 6; 8 (15):e012228 Epub 2019 Aug 05
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  79. Labinaz A, Marbach JA, Jung RG, Moreland R, Motazedian P, Di Santo P, Clancy AA, MacDonald Z, Simard T, Hibbert B, Ramirez FD. Female Authorship in Preclinical Cardiovascular Research: Temporal Trends and Influence on Experimental Design. JACC Basic Transl Sci. 2019 Aug; 4 (4):471-477 Epub 2019 Aug 26
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  80. Russo JJ, Aleksova N, Pitcher I, Couture E, Parlow S, Faraz M, Visintini S, Simard T, Di Santo P, Mathew R, So DY, Takeda K, Garan AR, Karmpaliotis D, Takayama H, Kirtane AJ, Hibbert B. Left Ventricular Unloading During Extracorporeal Membrane Oxygenation in Patients With Cardiogenic Shock. J Am Coll Cardiol. 2019 Feb 19; 73(6):654-662.
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  81. Russo JJ, Aleksova N, Pitcher I, Couture E, Parlow S, Faraz M, Visintini S, Simard T, Di Santo P, Mathew R, So DY, Takeda K, Gara AR, Karmapaliotis D. Takayama H, Kirtane A, Hibbert B. Left ventricular decompression during extracorporeal membrane oxygenation for cardiogenic shock: A systematic review and meta-analysis JACC. 2019; 73(6).
  82. Simard T, Jung R, Labinaz A, Faraz MA, Ramirez FD, Di Santo P, Pitcher I, Motazedian P, Gaudet C, Rochman R, Marbach J, Boland P, Sarathy K, Alghofaili S, Russo JJ, Couture E, Beanlands RS, Hibbert B. Adenosine as a Marker and Mediator of Cardiovascular Homeostasis: A Translational Perspective. Cardiovasc Hematol Disord Drug Targets. 2019; 19 (2):109-131
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  83. Mathew R, Santos G, Visintini S, Ramirez FD, Di Santo P, Simard T, Labinaz M, Hibbert B. Comparative efficacy of Milrinone and Dobutamine in Low cardiac Output States and Cardiogenic Shock: a Systematic Review and Meta-Analysis Clinical and Investigative Medicine. 2019. Epub 2021 Jan 01.
  84. Riberior IB, Dickie S, Nicholson D, Di Santo P. Aortic Dissection and Direct Factor Xa Inhibitors: Unchartered Waters Clinics in Surgery. 2018; 3(2177).
  85. Russo JJ, Di Santo P, Simard T, James TE, Hibbert B, Couture E, Marbach J, Osborne C, Ramirez FD, Wells GA, Labinaz M, Le May MR, from the CAPITAL study group. Optimal mean arterial pressure in comatose survivors of out-of-hospital cardiac arrest: An analysis of area below blood pressure thresholds. Resuscitation. 2018 Jul; 128:175-180 Epub 2018 Apr 22
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  86. Di Santo P, Motazedian P, Jung RG, Simard T, Ramirez FD, Chong AY, Glover C, Hibbert B, Dwivedi G. Evaluation of Cobalt and Chromium Levels Following Implantation of Cobalt Chromium Coronary Stents: A Pilot Study. Heart Lung Circ. 2018 Jun; 27 (6):763-766 Epub 2017 Dec 14
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  87. Di Santo P, Harnett DT, Simard T, Ramirez FD, Pourdjabbar A, Yousef A, Moreland R, Bernick J, Wells G, Dick A, Le May M, Labinaz M, So D, Motazedian P, Jung RG, Chandrasekhar J, Mehran R, Chong AY, Hibbert B. Photoplethysmography using a smartphone application for assessment of ulnar artery patency: a randomized clinical trial. CMAJ. 2018 Apr 3; 190 (13):E380-E388
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  88. Jung RG, Simard T, Labinaz A, Ramirez FD, Di Santo P, Motazedian P, Rochman R, Gaudet C, Faraz MA, Beanlands RSB, Hibbert B. Role of plasminogen activator inhibitor-1 in coronary pathophysiology. Thromb Res. 2018 Apr; 164:54-62 Epub 2018 Feb 20
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  89. Jung RG, Motazedian P, Ramirez FD, Simard T, Di Santo P, Visintini S, Faraz MA, Labinaz A, Jung Y, Hibbert B. Association between plasminogen activator inhibitor-1 and cardiovascular events: a systematic review and meta-analysis. Thromb J. 2018; 16:12 Epub 2018 June 05
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  90. Marbach JA, Feder J, Yousef A, Ramirez FD, Simard T, DiSanto P, Russo JJ, Boland P, Labinaz M, Glover C, Dick A, Hibbert B. Predicting Acute Kidney Injury following Transcatheter Aortic Valve Replacement. Clin Invest Med. 2017 Dec 17; 40 (6):E243-E251
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  91. Ramirez FD, Motazedian P, Jung RG, Di Santo P, MacDonald ZD, Moreland R, Simard T, Clancy AA, Russo JJ, Welch VA, Wells GA, Hibbert B. Methodological Rigor in Preclinical Cardiovascular Studies: Targets to Enhance Reproducibility and Promote Research Translation. Circ Res. 2017 Jun 9; 120 (12):1916-1926 Epub 2017 Apr 03
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  92. Di Santo P, Simard T, Marquis JF, Hibbert B. Left Atrial Dissection After Percutaneous Transluminal Mitral Valvuloplasty. Can J Cardiol. 2017 Jun; 33 (6):831.e5-831.e6 Epub 2017 Mar 02
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  93. Ramirez FD, Chen Y, Di Santo P, Simard T, Motazedian P, Hibbert B. Association Between Self-Reported Potentially Modifiable Cardiac Risk Factors and Perceived Need to Improve Physical Health: A Population-Based Study. J Am Heart Assoc. 2017 May 3; 6 (5) Epub 2017 May 03
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  94. Simard T, Jung RG, Motazedian P, Di Santo P, Ramirez FD, Russo JJ, Labinaz A, Yousef A, Anantharam B, Pourdjabbar A, Hibbert B. Progenitor Cells for Arterial Repair: Incremental Advancements towards Therapeutic Reality. Stem Cells Int. 2017; 2017:8270498. Epub 2017 Jan 23.
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  95. Simard T, Hibbert B, Natarajan MK, Mercuri M, Hetherington SL, Wright R, Delewi R, Piek JJ, Lehmann R, Ruzsa Z, Lange HW, Geijer H, Sandborg M, Kansal V, Bernick J, Di Santo P, Pourdjabbar A, Ramirez FD, Chow BJ, Chong AY, Labinaz M, Le May MR, O'Brien ER, Wells GA, So D. Impact of Center Experience on Patient Radiation Exposure During Transradial Coronary Angiography and Percutaneous Intervention: A Patient-Level, International, Collaborative, Multi-Center Analysis. J Am Heart Assoc. 2016 May 31; 5(6).
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  96. Di Santo P, Simard T, Ramirez FD, Pourdjabbar A, Harnett DT, Singh K, Moreland R, Chong AY, Dick A, Labinaz M, Froeschl M, Froeschl M, Le May MR, So DY, Hibbert B. Does stent strut design impact clinical outcomes: comparative safety and efficacy of Endeavor Resolute versus Resolute Integrity zotarolimus-eluting stents. Clin Invest Med. 2015 Oct 07; 38(5):E296-304.
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