المتخصصون في المجالات الطبية

تتوفر أدناه التجارب السريرية الحالية.

تصفية قائمة الدراسات هذه حسب الموقع، والحالة والمزيد.

1. A Study Of Larsucosterol In Alcohol-associated Hepatitis

   Scottsdale/Phoenix, Ariz., Jacksonville, Fla.

   The purpose of this study is to evaluate the safety and efficacy of larsucosterol, as determined by transplant-free survival through Day 90, in participants with severe alcohol-associated hepatitis (AH) with pre-treatment Maddrey Discriminant Function (MDF) score ≥ 32 and MELD scores 21-30, inclusive.

2. A Study Of Senseera Liquid Biopsy In Detecting ACR

   Jacksonville, Fla.

   The purpose of the study is to optimize and validate the performance of the Senseera liquid biopsy cfChIP-seq assay for the detection of Acute Cellular Rejection (ACR) of the liver in patients who underwent a liver graft, as compared to the standard of care biopsy of the liver and histopathological examination by specialized pathologists.

   The sensitivity and specificity of the test will be compared to the reference standard, based on the biopsy results, and the overall diagnostic accuracy of the assay will be assessed.

3. Study Of Gastric Cancer And Limited Peritoneal Metastasis Using Robotic Cytoreduction And Hyperthermic Intraperitoneal Chemotherapy

   Rochester, Minn.

   The purpose of this study is to assess short-term morbidity and disease-free survival outcomes for patients with gastric adenocarcinoma with limited low volume peritoneal metastasis and/or positive peritoneal cytology undergoing robotic cytoreduction and hyperthermic intraperitoneal chemotherapy.

4. Study to Better Understand the Development of Irritable Bowel Disease (IBD) and Related Diseases as a Step Toward Improving Disease Outcomes.

   Rochester, Minn.

   The purpose of this study is to better understand disease development of Irritiable Bowel Disease (IBD) and related diseases as a step to improving disease outcomes.

5. Early Pancreatic Cancer Detection

   Jacksonville, Fla.

   The primary purpose of this study is to standardize the collection of demographic, clinical, and imaging data, and biosamples for a large high-risk familial Pancreatic Ductal Adenocarinoma (PDAC) cohort at consortium clinical cancer centers, worldwide.

6. A Study to Evaluate the Effectiveness of a Healthy Living Weight Loss Program in Obese Patients Undergoing Bariatric Endoscopy on Weight Loss Outcomes

   Rochester, Minn.

   The purpose of this study is to compare weight loss, improvement of comorbidities, improvement of lipid profile, blood sugar in patients undergoing endoscopic sleeve gastroplasty or intragastric balloon between patients who are in a weight loss program and those who are not.

7. Validation Of DNA Methylation Markers For Universal And Site-specific Guided Cancer Detection, VANGUARD Study

   Rochester, Minn.

   This study explores the potential value of a new blood test approach for early detection of cancer.

8. A Study to Better Understand Why Patients Gain Weight After Undergoing Liver Transplantation

   Rochester, Minn.

   The purpose of this study is to understanding the mechanisms of weight gain in patients following liver transplantation, action, and indicate approaches to prevent weight gain.

9. Transforming Healthcare And Outcomes For Children With Inflammatory Bowel Disease

   Rochester, Minn., La Crosse, Wis., Mankato, Minn., Eau Claire, Wis.

   The purpose is to put the information into a very large database, which can then be used to improve patient care and achieve the best health outcomes possible for children with IBD.

10. Genomic and Environmental Basis of Imperforate Anus

    Rochester, Minn.

    The study aims are to develop a consent-based IRB proposal that will enroll newborns who have imperforate anus.  The proposal will include permission for chart review and database information storage, to develop a database that will include MRN, imperforate anus phenotype, information on other congenital malformations, syndromic diagnosis if available, demographic information, and to develop a biobank of DNA and white blood cell samples from infants with imperforate anus. If patients are undergoing a skin biopsy for a medically indicated reason, cells will be requested.

    Imperforate Anus, also known as anal atresia, is a rare birth defect.  Unable to pass stool through the gastrointestinal tract, this condition can result in death of the newborn and emergency surgery is required once discovered.  More than two thirds of affected infants have other birth defects that include other parts of the gastrointestinal tract, airway, heart, skeleton, kidneys, eyes, or ears. The exact prevalence of imperforate anus in the newborn population is unknown.