المتخصصون في المجالات الطبية

تتوفر أدناه التجارب السريرية الحالية.

83 الدراسات في Cardiovascular Diseases and Cardiac Surgery
(الدراسات المفتوحة فقط).

تصفية قائمة الدراسات هذه حسب الموقع، والحالة والمزيد.

1. A Study of Ticagrelor in the Upstream Setting for Non-ST-Segment Elevation Myocardial Infarction

   Jacksonville, Fla.

   The purpose of this study is to establish a registry that will address the data gap regarding the course of NSTEMI (Non-ST-Elevation Myocardial Infarction) between ED (Emergency Department) arrival and diagnostic angiography in detail, by characterizing and following the ED and peri-ED use of advanced OAP (Oral Anti-Platelet) agents. In addition to exploring ED treatment patterns and success of both ischemic and bleeding risk stratification prior to definition of the coronary anatomy, data generated via the UPSTREAM registry will allow plausible attribution of ischemic and bleeding outcomes to pre-catheterization antiplatelet therapy in the management of NSTEMI. This registry further seeks to demonstrate that contemporary use of upstream ticagrelor is associated with an economically-sound utilization of hospital resources, and smooth transition of care into the outpatient, secondary prevention setting for the first 30 days after hospitalization. Finally, it will allow characterization of patient selection factors and processes for ticagrelor vs alternative OAP agents, carrying out that descriptive comparison through discharge. Patients transferred in to an UPSTREAM hospital are eligible for inclusion, but the timing for OAP agent administration and diagnostic catheterization begin with ED care at the first hospital.

2. A Study To Evaluate Endovascular Ablation Of The Right Greater Splanchnic Nerve In Subjects Having Heart Failure With Preserved Ejection Fraction

   Rochester, Minn.

   The objective of this clinical evaluation is to assess the safety and initial effectiveness of catheter-based unilateral ablation of the right greater splanchnic nerve (GSN) in subjects having heart failure with preserved ejection fraction (HFpEF).

3. Associated Anomalies with Right and Left Cusp Fusion Versus Right and Non-Coronary Cusp Fusion

   Rochester, Minn.

   The goal of this study is to determine whether significant differences exist in the prevalence of associated cardiac anomalies between right/left and right / non-coronary cusp fusion in bicuspid aortic valve.

4. Multimodality Evaluation of Left Ventricular Remodeling

   Rochester, Minn.

   The purpose of this study is to use a multimodal approach to mitral valve evaluation using cardiac CT and MRI, which have shown superior accuracy in assessing anatomic and functional parameters relative to standard-of-care echocardiography. By evaluating 30 patients undergoing robotic mitral annuloplasty, this study aims to establish the feasibility of further prospective evaluation of CT and MRI for preoperative risk stratification. Enhanced risk stratification could significantly improve patient outcomes.

    

5. The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry

   Rochester, Minn.

   The primary goal of this project is to describe the clinical and physiologic characteristics of Spontaneous Coronary Artery Dissections (SCAD) in order to increase awareness, understanding, treatment and prevention of a potentially fatal cardiovascular event.

   This study will be a retrospective and prospective review of medical course and current health of men and women with SCAD.

6. A Study To Develop A Pulmonary Hypertension Association Registry (PHAR)

   Rochester, Minn.

   The primary purpose of this study is to measure and improve quality of care (including assessing differences in adherence to evidence-based guidelines and establishing benchmarks for health outcomes).

7. A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium

   Rochester, Minn.

   The purpose of this study is to evaluate the effect of a pre-ICU admission simulation session on post-operative delirium in the elective cardiothoracic surgical population while in the intensive care unit.

    

    

    

8. International Triadin Knockout Syndrome Registry

   Rochester, Minn.

   The aim of this study is to determine the worldwide prevalence of Triadin Knockout Syndrome (TKOS), and to better define the phenotype of patients with the disease. This information will provide additional insight into which phenotypic markers may be specific to TKOS, and will also help to develop better TKOS specific treatment strategies.

9. A Study to Evaluate Potential Myocardial Injury Following Elective Direct Current Cardioversion

   Rochester, Minn.

   The purpose of this study is to prospectively determine if direct current cardioversion (DCCV) results in myocardial injury as assessed by changes in high sensitivity cardiac troponin T (hs-cTnT) assay.

10. A Study of Arrhythmia in Eisenmenger’s Syndrome

    Rochester, Minn., Jacksonville, Fla.

    The purpose of this study is to describe the incidence and type of arrhythmia seen in patients with Eisenmenger syndrome, to define predisposing factors potentially leading to the onset of arrhythmia, and to describe the influence of arrhythmia on outcomes.