Brand Name

    US Brand Name

    Xipere


    Description

    Triamcinolone suprachoroidal injection is used to treat macular edema associated with uveitis (redness, pain, or swelling of the eye). Macular edema is swelling in the back of the eye and may cause vision loss.

    Triamcinolone injection is also used to treat inflammation of the eyes. This medicine is also used to help see the eyes during a procedure called vitrectomy. Triamcinolone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

    This medicine is to be given only by or under the direct supervision of your doctor.

    This product is available in the following dosage forms:

    • Suspension

    Before Using

    In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Appropriate studies have not been performed on the relationship of age to the effects of triamcinolone suprachoroidal injection in the pediatric population. Safety and efficacy have not been established.

    Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of triamcinolone injection in the pediatric population. However, pediatric patients are more likely to have slower growth and bone problems if triamcinolone injection is used for a long time.

    Geriatric

    Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of triamcinolone suprachoroidal injection in the elderly. However, elderly patients are more likely to have unwanted effects (eg, osteoporosis), which may require caution in patients receiving this medicine.

    Breastfeeding

    There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

    Drug Interactions

    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

    Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

    • Desmopressin
    • Mifepristone

    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

    • Aldesleukin
    • Aspirin
    • Atazanavir
    • Balofloxacin
    • Bemiparin
    • Besifloxacin
    • Carbamazepine
    • Ceritinib
    • Ciprofloxacin
    • Cobicistat
    • Cosyntropin
    • Darunavir
    • Enoxacin
    • Ethinyl Estradiol
    • Fleroxacin
    • Flumequine
    • Fosphenytoin
    • Gatifloxacin
    • Gemifloxacin
    • Insulin Aspart, Recombinant
    • Insulin Glargine, Recombinant
    • Insulin Icodec-abae
    • Levofloxacin
    • Lomefloxacin
    • Lutetium Lu 177 Dotatate
    • Macimorelin
    • Moxifloxacin
    • Nadifloxacin
    • Nadroparin
    • Nirmatrelvir
    • Norfloxacin
    • Ofloxacin
    • Pazufloxacin
    • Pefloxacin
    • Phenytoin
    • Prulifloxacin
    • Relacorilant
    • Ritonavir
    • Rufloxacin
    • Sargramostim

    Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

    • Alcuronium
    • Atracurium
    • Auranofin
    • Bendroflumethiazide
    • Benzthiazide
    • Bumetanide
    • Chlorothiazide
    • Chlorthalidone
    • Clopamide
    • Cyclopenthiazide
    • Cyclothiazide
    • Diazoxide
    • Ethacrynic Acid
    • Etozolin
    • Furosemide
    • Gallamine
    • Hexafluorenium
    • Hydrochlorothiazide
    • Hydroflumethiazide
    • Licorice
    • Methyclothiazide
    • Metocurine
    • Metolazone
    • Piretanide
    • Primidone
    • Quinethazone
    • Rotavirus Vaccine, Live
    • Saiboku-To
    • Torsemide
    • Trichlormethiazide
    • Xipamide

    Other Interactions

    Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

    Other Medical Problems

    The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

    • Adrenal gland problems or
    • Cataracts or
    • Glaucoma or
    • Heart attack, recent or
    • Heart failure or
    • Herpes infection of the eye, history of or
    • Hypertension (high blood pressure) or
    • Kidney disease or
    • Mental health problems (eg, psychosis) or
    • Myasthenia gravis (severe muscle weakness) or
    • Stomach or bowel problems (eg, diverticulitis, ulcers, perforation) or
    • Thyroid problems (eg, overactive or underactive thyroid)—Use with caution. May make these conditions worse.
    • Cerebral malaria or
    • Fungal eye infection or
    • Herpes infection of the eye, active or
    • Mycobacterial eye infection or
    • Vaccinia (smallpox) eye infection or
    • Varicella (chickenpox) eye infection—Should not be used in patients with these conditions.
    • Infection (bacteria, virus, fungus, parasite, or protozoa)—May decrease your body's ability to fight infection.

    Proper Use

    Your eye doctor (ophthalmologist) will give you this medicine in a hospital or clinic. It is given as a shot into the eye.


    Precautions

    Your eye doctor will want to check your progress at regular visits, especially during the first few days after you receive this medicine, to make sure this medicine is working properly and to check for unwanted effects.

    Serious eye problems (eg, cataracts, glaucoma, detached retina, eye infection or swelling) may occur after receiving this medicine. Check with your eye doctor right away if you have blindness, blurred vision, change in vision, eye pain, headache, nausea or vomiting, seeing flashes or sparks of light, seeing floating spots before the eyes, or a veil or curtain appearing across part of vision, or tearing. Also, tell your doctor if you feel an increased pressure in the eye.

    Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor right away if you or your child have blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness.

    This medicine may cause you or your child to get more infections than usual. Avoid people who are sick or have infections and wash your hands often. If you or your child are exposed to chickenpox or measles, tell your doctor right away. If you or your child start to have a fever, chills, sore throat, or any other sign of an infection, call your doctor right away.

    This medicine may cause high blood pressure and salt and water retention. Check with your doctor right away if you have dizziness, headache, irregular heartbeat, nosebleeds, numbness or tingling in the face, arms, or legs, swelling in the hands and feet, trouble breathing, or weight gain. Carefully follow your doctor's instructions about any special diet (especially on salt intake).

    Check with your doctor right away if you have bloody, black, or tarry stools, heartburn, indigestion, nausea, stomach pain, cramps, or burning, trouble breathing, or vomiting of material that looks like coffee grounds, severe and continuing. These may be symptoms of stomach or bowel problems.

    Check with your doctor right away if you have changes in personality, discouragement, false or unusual sense of well-being, feeling sad or empty, irritability, lack of appetite, loss of interest or pleasure, tiredness, trouble concentrating, or trouble sleeping. These may be symptoms of changes in mood or behavior.

    This medicine may cause children to grow more slowly than usual. Talk to your child's doctor if you have any concerns.

    This medicine may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, ask your doctor.

    Check with your doctor right away if you have muscular pain, tenderness, wasting, or weakness. These may be symptoms of a serious muscle problem.

    While you are being treated with triamcinolone injection, do not have any immunizations (vaccines) without your doctor's approval. Triamcinolone may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. If you have questions about this, talk to your doctor.

    This medicine may increase your risk for cancer, including Kaposi's sarcoma. Tell your doctor right away if you have flat, painless spots that are red or purple on white skin or bluish, brownish, or black on dark skin.

    Before you have any skin tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.

    Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium.

    Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


    Side Effects

    Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor or nurse immediately if any of the following side effects occur:

    More common

    • Blindness
    • blurred vision
    • change in vision
    • eye pain
    • increased pressure in the eye
    • loss of vision
    • seeing flashes or sparks of light
    • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision

    Less common

    • Bloody eye
    • change in color vision
    • difficulty seeing at night
    • drooping upper eyelids
    • increased sensitivity of the eyes to sunlight
    • painful irritation of the clear front part of the eye
    • swelling or redness of the eye or inside of the eyelids
    • tearing

    Incidence not known

    • Backache
    • bloating
    • blue lips and fingernails
    • burning, tingling, numbness or pain in the hands, arms, feet, or legs
    • chest pain, discomfort, or tightness
    • chills
    • confusion
    • constipation
    • cough
    • coughing that sometimes produces a pink frothy sputum
    • darkening of the skin
    • decrease in amount of urine
    • decrease in height
    • diarrhea
    • difficulty swallowing
    • dilated neck veins
    • discouragement
    • dizziness
    • drowsiness
    • dry mouth
    • facial hair growth in females
    • fainting
    • false or unusual sense of well-being
    • feeling sad or empty
    • flushed, dry skin
    • fractures
    • fruit-like breath odor
    • full or round face, neck, or trunk
    • hives, itching, skin rash
    • increased hunger
    • increased thirst or urination
    • irritability
    • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    • lightheadedness, dizziness, or fainting
    • loss of appetite
    • loss of interest or pleasure
    • loss of sexual desire or ability
    • menstrual irregularities
    • mental depression
    • muscle wasting or weakness
    • nausea
    • pain in the back, ribs, arms, or legs
    • pain in the chest, groin, or legs, especially the calves
    • pains in stomach, side, or abdomen, possibly radiating to the back
    • pale skin
    • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    • right upper abdominal and stomach pain and fullness
    • seizures
    • sensation of pins and needles
    • slow or irregular heartbeat
    • slurred speech
    • stabbing pain
    • stiff neck or back
    • sudden, severe weakness or numbness in the arm or leg
    • sweating
    • swelling of the face, fingers, feet, or lower legs
    • trouble breathing
    • trouble concentrating
    • trouble sleeping
    • unexplained weight loss
    • unusual tiredness or weakness
    • vomiting
    • weight gain
    • yellow eyes or skin

    Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    More common

    • Headache

    Incidence not known

    • Blemishes on the skin
    • hiccups
    • pimples
    • small red or purple spots on the skin

    Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.






    DRG-20524772

    عطاؤك له أثر كبير — تبرَّع الآن!

    تساهم التبرّعات، وهي قابلة للخصم الضريبي، في دعم آخر التطورات في الأبحاث وطرق الرعاية لإحداث نقلة نوعية في الطب.