Description and Brand Names

Drug information provided by: Merative, Micromedex®

US Brand Name

  1. Darzalex

Descriptions


Daratumumab injection is used alone or together with other medicines to treat multiple myeloma (a type of bone marrow cancer). It is used alone in patients who have received at least 3 prior treatments that did not work well, including a proteasome inhibitor and an immunomodulatory agent, or who did not respond to both a proteasome inhibitor and an immunomodulatory agent.

Daratumumab injection is also used in combination with lenalidomide and dexamethasone to treat patients with newly diagnosed multiple myeloma who cannot receive autologous stem cell transplant and patients with relapsed (cancer that has come back) or refractory (cancer that did not respond to treatment) multiple myeloma who have received at least 1 previous treatment.

Daratumumab injection is also used together with bortezomib, melphalan, and prednisone to treat patients with newly diagnosed multiple myeloma who cannot receive autologous stem cell transplant.

Daratumumab injection is also used together with bortezomib, thalidomide, and dexamethasone to treat patients with newly diagnosed multiple myeloma who can receive autologous stem cell transplant.

Daratumumab injection is also used in combination with bortezomib and dexamethasone to treat patients with multiple myeloma who have received at least 1 previous treatment.

Daratumumab injection is also used in combination with carfilzomib and dexamethasone to treat patients with relapsed (cancer that has come back) or refractory (cancer that did not respond to treatment) multiple myeloma who have received 1 to 3 previous treatments.

Daratumumab injection is also used in combination with pomalidomide and dexamethasone to treat patients with multiple myeloma who have received at least two treatments (including lenalidomide and a proteasome inhibitor).

This medicine is to be given only by or under the supervision of your doctor.

This product is available in the following dosage forms:

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