الجراحة

بالأسفل التجارب السريرية الحالية.

غربل قائمة الدراسات هذه بالموقع والحالة وغيرها.

1. Optimizing Rehabilitation Effect With Electrical Stimulation Therapy Rehab

   Jacksonville, Fla., Rochester, Minn.

   The purpose of this study is to evaluate the safety and effectiveness of deep brain stimulation (DBS) of the dentate nucleus area for improving functional status in patients with moderate to severe residual upper-extremity motor impairment due to stroke.

    

    

2. A Study to Evaluate Outcomes of Pectoralis Minor and Brachial Plexus Release

   Rochester, Minn.

   The purpose of this study is to to assess the clinical and radiographic outcomes of patients who have undergone shoulder arthroplasty.

3. Mayo Clinic Cardiovascular Disease Biobank

   Rochester, Minn.

   The purpose of this study is to determine the innate immune, cell death and oxidative stress changes in the myocardium, and aorta of patients with heart failure compared to patients with normal hearts.

4. Trifecta-Lung CfDNA-MMDx Study

   Jacksonville, Fla.

   The purpose of this study is to demonstrate the relationship between dd-cfDNA levels and HLA antibodies in blood transplant recipient and Demonstrate the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from lung transplants.

5. A Study Of Intravital Microscopy (IVM) In Human Solid Tumors

   Jacksonville, Fla.

   The purpose of this study is to determine the feasibility of performing HIVM in patients with deep space solid tumors during standard course of surgical resection.

6. Testing Docetaxel-Cetuximab Or The Addition Of An Immunotherapy Drug, Atezolizumab, To The Usual Chemotherapy And Radiation Therapy In High-Risk Head And Neck Cancer

   Rochester, Minn.

   This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cetuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to compare the usual treatment (radiation therapy with cisplatin chemotherapy) to using radiation therapy with docetaxel and cetuximab chemotherapy, and using the usual treatment plus an immunotherapy drug, atezolizumab.

7. Cognitive Advancement and Recovery in VNS-Rehabilitation (CARE)

   Rochester, Minn.

   The purpose of this study is to investigate whether VNS therapy leads to any changes in the cognitive functions of individuals who have survived a stroke.

8. A Study to Evaluate Manipulation Under Anesthesia After Bilateral Primary Total Knee Arthroplasty

   Rochester, Minn.

   The purpose of this study is to determine unique genetic profile of patients requiring MUA following bilateral pTKA via genetic sequencing, to determine outcomes of patients receiving MUA in terms of KSS, implant durability, survival free of reoperation, and to define characteristics and comorbidities of patients undergoing unilateral and bilateral MUA.

9. A Study to Evaluate Awake vs. Asleep Spine Surgery

   Jacksonville, Fla.

   Patients undergoing spine lumbar surgery will be asked to perform short exams/questionnaires aimed at determining cognitive function, quality of life, health outcomes twice post surgery with a baseline performance prior to surgery.

10. Renal Intervention For Chronic Hypertension Pilot Trial Using The Verve Medical RPDTM System (RPD Pilot Trial)

    Rochester, Minn.

    The RPD Pilot trial will evaluate the safety and effectiveness of Verve Medical's RPDTM renal denervation system for hypertensive patients with uncontrolled blood pressure, despite use of two anti-hypertensive medications and lifestyle changes. The novelty of the RPDTM system relates to its placement via natural orifice into the pelvis of the kidney (bilaterally) for delivery of radiofrequency energy to ablate the nerves that pass through the outer wall of the renal pelvis, a technique referred to as renal pelvic denervation (RPD).

بالأسفل التجارب السريرية الحالية.

غربل قائمة الدراسات هذه بالموقع والحالة وغيرها.

1. Optimizing Rehabilitation Effect With Electrical Stimulation Therapy Rehab

   Jacksonville, Fla., Rochester, Minn.

   The purpose of this study is to evaluate the safety and effectiveness of deep brain stimulation (DBS) of the dentate nucleus area for improving functional status in patients with moderate to severe residual upper-extremity motor impairment due to stroke.

    

    

2. A Study to Evaluate Outcomes of Pectoralis Minor and Brachial Plexus Release

   Rochester, Minn.

   The purpose of this study is to to assess the clinical and radiographic outcomes of patients who have undergone shoulder arthroplasty.

3. Mayo Clinic Cardiovascular Disease Biobank

   Rochester, Minn.

   The purpose of this study is to determine the innate immune, cell death and oxidative stress changes in the myocardium, and aorta of patients with heart failure compared to patients with normal hearts.

4. Trifecta-Lung CfDNA-MMDx Study

   Jacksonville, Fla.

   The purpose of this study is to demonstrate the relationship between dd-cfDNA levels and HLA antibodies in blood transplant recipient and Demonstrate the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from lung transplants.

5. A Study Of Intravital Microscopy (IVM) In Human Solid Tumors

   Jacksonville, Fla.

   The purpose of this study is to determine the feasibility of performing HIVM in patients with deep space solid tumors during standard course of surgical resection.

6. Testing Docetaxel-Cetuximab Or The Addition Of An Immunotherapy Drug, Atezolizumab, To The Usual Chemotherapy And Radiation Therapy In High-Risk Head And Neck Cancer

   Rochester, Minn.

   This phase II/III trial studies how well radiation therapy works when given together with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating patients with high-risk stage III-IV head and neck cancer the begins in the thin, flat cells (squamous cell). Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Cetuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to compare the usual treatment (radiation therapy with cisplatin chemotherapy) to using radiation therapy with docetaxel and cetuximab chemotherapy, and using the usual treatment plus an immunotherapy drug, atezolizumab.

7. Cognitive Advancement and Recovery in VNS-Rehabilitation (CARE)

   Rochester, Minn.

   The purpose of this study is to investigate whether VNS therapy leads to any changes in the cognitive functions of individuals who have survived a stroke.

8. A Study to Evaluate Manipulation Under Anesthesia After Bilateral Primary Total Knee Arthroplasty

   Rochester, Minn.

   The purpose of this study is to determine unique genetic profile of patients requiring MUA following bilateral pTKA via genetic sequencing, to determine outcomes of patients receiving MUA in terms of KSS, implant durability, survival free of reoperation, and to define characteristics and comorbidities of patients undergoing unilateral and bilateral MUA.

9. A Study to Evaluate Awake vs. Asleep Spine Surgery

   Jacksonville, Fla.

   Patients undergoing spine lumbar surgery will be asked to perform short exams/questionnaires aimed at determining cognitive function, quality of life, health outcomes twice post surgery with a baseline performance prior to surgery.

10. Renal Intervention For Chronic Hypertension Pilot Trial Using The Verve Medical RPDTM System (RPD Pilot Trial)

    Rochester, Minn.

    The RPD Pilot trial will evaluate the safety and effectiveness of Verve Medical's RPDTM renal denervation system for hypertensive patients with uncontrolled blood pressure, despite use of two anti-hypertensive medications and lifestyle changes. The novelty of the RPDTM system relates to its placement via natural orifice into the pelvis of the kidney (bilaterally) for delivery of radiofrequency energy to ablate the nerves that pass through the outer wall of the renal pelvis, a technique referred to as renal pelvic denervation (RPD).