الطب المختبري وعلم الأمراض

بالأسفل التجارب السريرية الحالية.

19 دراسات في الطب المختبري وعلم الأمراض
(افتح الدراسات فقط).

غربل قائمة الدراسات هذه بالموقع والحالة وغيرها.

1. Clinical Biochemical Genetic Assays Associated with Inborn Errors of Metabolism and Other Heritable or Congenital Conditions

   Rochester, Minn.

   The objectives of this protocol are to develop and validate clinical assays for inborn errors of metabolism (IEMs) using specimens collected from consenting individuals who have a confirmed diagnosis of an IEM or are a first degree relative of an individual with an IEM and to improve the diagnosis of IEMs by establishing and/or refining disease ranges for each analyte measured and to improve the care of these patients by reducing the number of false positive results and unnecessary follow-up.

2. Device Evaluation for Point of Care Anticoagulation Testing

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is:

   • To Evaluate and validate the Roche Coaguchek XS Plus analyzer at MCA to replace the ITC Hemochron Jr. Signature + for fingerstick INR.
   • To familiarize the Coumadin Clinic nurses with the new POC device
   • To develop a compliance plan for daily operation..

3. A Study to Analyze Whole Methylome for Identification of Epigenetic Variations in Undiagnosed Congenital Disorders

   Rochester, Minn.

   The purpose of this study is to analyze genome-wide methylation patterns in DNA from patients with suspected hereditary disorders but for whom all previous genetic testing has been negative and/or equivocal.

4. A Study to Evaluate the QuantiFERON-TB Gold-Plus Test for Blood Detection of Tuberculosis without Symptoms

   Rochester, Minn.

   The purpose of this study is to evaluate the new QFT-Plus assay compared to the QFT-Gold assay and the tuberculin skin test results (as available) for the detection of tuberculosis without symptoms in high-risk patients.

                  

5. A Study to Create a Biobank of Fallopian Tube Organoids (Small, Simplified Organs) in Women Undergoing Salpingectomy (Surgical Removal of the Fallopian Tubes)

   Rochester, Minn., Jacksonville, Fla.

   The aim of this study is to develop and bank organoids for collaborative use in subsequent etiological, biomarker and chemoprevention studies that will culminate in launching chemoprevention trials at Mayo.

6. Collection of Peripheral Blood Mononuclear Cells from Normal Healthy Donors via Apheresis for use in Laboratory Development Studies

   Rochester, Minn.

   The purpose of this research protocol is to systematically investigate the optimal conditions for isolating and culturing (referred to as manufacturing) of mononuclear cells (MNCs) from healthy volunteers collected via apheresis.

7. Circulating Tumor Nucleic Acids to Monitor Treatment Response in Metastatic Melanoma Patients

   Scottsdale/Phoenix, Ariz.

   This project will investigate whether the analysis of nucleic acids circulating in the blood from tumors can allow real-time monitoring of treatment response to targeted therapy and immunotherapy for patients who have stage IV metastatic melanoma.

8. A Study of the Health Issues of Bleeding Disorders

   Rochester, Minn.

   The purpose of this study is to monitor and better understand the health issues of people with bleeding disorders.

9. Allogeneic Mesenchymal Stromal Cell Donor Bank

   Rochester, Minn.

   The purpose of this study is to collect adipose tissue from patients undergoing elective surgery, or from healthy volunteers, test the donors to assure that they comply with all regulatory aspects required of healthy donors, expand and test mesenchymal stromal cells (MSC), and bank them for future use.