المنشورات طباعة Garmany R, Castrichini M, Neves R, Pereira NL, MacIntyre C, Schneider JW, Ackerman MJ, Giudicessi JR. Age at onset and clinical course of RBM20-mediated cardiomyopathy. Sci Rep. 2025 Mar 28; 15 (1):10716 View PubMed Clemens DJ, Ye D, Zhou W, Kim CSJ, Pease DR, Navaratnarajah CK, Barkhymer A, Tester DJ, Nelson TJ, Cattaneo R, Schneider JW, Ackerman MJ. SARS-CoV-2 spike protein-mediated cardiomyocyte fusion may contribute to increased arrhythmic risk in COVID-19. PLoS One. 2023; 18(3):e0282151. Epub 2023 Mar 08. View PubMed Navaratnarajah CK, Pease DR, Halfmann PJ, Taye B, Barkhymer A, Howell KG, Charlesworth JE, Christensen TA, Kawaoka Y, Cattaneo R, Schneider JW, Wanek Family Program for HLHS-Stem Cell Pipeline. Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition. J Virol. 2021 Nov 23; 95(24):e0136821. Epub 2021 Oct 06. View PubMed Schneider JW, Oommen S, Qureshi MY, Goetsch SC, Pease DR, Sundsbak RS, Guo W, Sun M, Sun H, Kuroyanagi H, Webster DA, Coutts AW, Holst KA, Edwards BS, Newville N, Hathcock MA, Melkamu T, Briganti F, Wei W, Romanelli MG, Fahrenkrug SC, Frantz DE, Olson TM, Steinmetz LM, Carlson DF, Nelson TJ, Wanek Program Preclinical Pipeline. Author Correction: Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs. Nat Med. 2021 Jul; 27(7):1309. View PubMed Schneider JW, Oommen S, Qureshi MY, Goetsch SC, Pease DR, Sundsbak RS, Guo W, Sun M, Sun H, Kuroyanagi H, Webster DA, Coutts AW, Holst KA, Edwards BS, Newville N, Hathcock MA, Melkamu T, Briganti F, Wei W, Romanelli MG, Fahrenkrug SC, Frantz DE, Olson TM, Steinmetz LM, Carlson DF, Nelson TJ, Wanek Program Preclinical Pipeline. Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs. Nat Med. 2020 Nov; 26 (11):1788-1800 Epub 2020 Nov 13 View PubMed Zheng C, Schneider JW, Hsieh J. Role of RB1 in human embryonic stem cell-derived retinal organoids. Dev Biol. 2020 Jun 15; 462 (2):197-207 Epub 2020 Mar 19 View PubMed Burchfield JS, Paul AL, Lanka V, Tan W, Kong Y, McCallister C, Rothermel BA, Schneider JW, Gillette TG, Hill JA. Pharmacological priming of adipose-derived stem cells promotes myocardial repair J Investig Med. 2019; 64(1):500-62. View PubMed Altamirano F, Schiattarella GG, French KM, Kim SY, Engelberger F, Kyrychenko S, Villalobos E, Tong D, Schneider JW, Ramirez-Sarmiento CA, Lavandero S, Gillette TG, Hill JA. Polycystin-1 Assembles With Kv Channels to Govern Cardiomyocyte Repolarization and Contractility. Circulation. 2019 Sep 10; 140(11):921-936. Epub 2019 Jun 21. View PubMed Parra V, Altamirano F, Hernández-Fuentes CP, Tong D, Kyrychenko V, Rotter D, Pedrozo Z, Hill JA, Eisner V, Lavandero S, Schneider JW, Rothermel BA. Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network. Circ Res. 2018 Mar 16; 122(6):e20-e33. Epub 2018 Jan 23. View PubMed Meng XL, Arning E, Wight-Carter M, Day TS, Jabbarzadeh-Tabrizi S, Chen S, Ziegler RJ, Bottiglieri T, Schneider JW, Cheng SH, Schiffmann R, Shen JS. Priapism in a Fabry disease mouse model is associated with upregulated penile nNOS and eNOS expression. J Inherit Metab Dis. 2018 Mar; 41(2):231-238. Epub 2017 Nov 06. View PubMed Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing. Sci Adv. 2018 Jan; 4(1):eaap9004. Epub 2018 Jan 31. View PubMed Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton JM, Long C, Schneider JW, Zimmermann WH, Bassel-Duby R, Olson EN. Functional correction of dystrophin actin binding domain mutations by genome editing. JCI Insight. 2017 Sep 21; 2(18). View PubMed Matsui T, Nieto-Estévez V, Kyrychenko S, Schneider JW, Hsieh J. Retinoblastoma protein controls growth, survival and neuronal migration in human cerebral organoids. Development. 2017 Mar 15; 144(6):1025-1034. Epub 2017 Jan 13. View PubMed Li DL, Wang ZV, Ding G, Tan W, Luo X, Criollo A, Xie M, Jiang N, May H, Kyrychenko V, Schneider JW, Gillette TG, Hill JA. Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome Acidification. Circulation. 2016 Apr 26; 133(17):1668-87. Epub 2016 Mar 16. View PubMed Kalwat MA, Huang Z, Wichaidit C, McGlynn K, Earnest S, Savoia C, Dioum EM, Schneider JW, Hutchison MR, Cobb MH. Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in ß-Cells. ACS Chem Biol. 2016 Apr 15; 11(4):1128-36. Epub 2016 Feb 10. View PubMed Morales CR, Li DL, Pedrozo Z, May HI, Jiang N, Kyrychenko V, Cho GW, Kim SY, Wang ZV, Rotter D, Rothermel BA, Schneider JW, Lavandero S, Gillette TG, Hill JA. Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression. Sci Signal. 2016 Apr 05; 9(422):ra34. View PubMed Zhu M, Goetsch SC, Wang Z, Luo R, Hill JA, Schneider J, Morris SM Jr, Liu ZP. FoxO4 promotes early inflammatory response upon myocardial infarction via endothelial Arg1. Circ Res. 2015 Nov 6; 117 (11):967-77 Epub 2015 Oct 05 View PubMed Shen JS, Meng XL, Wight-Carter M, Day TS, Goetsch SC, Forni S, Schneider JW, Liu ZP, Schiffmann R. Blocking hyperactive androgen receptor signaling ameliorates cardiac and renal hypertrophy in Fabry mice. Hum Mol Genet. 2015 Jun 01; 24(11):3181-91. Epub 2015 Feb 20. View PubMed Singh S, Canseco DC, Manda SM, Shelton JM, Chirumamilla RR, Goetsch SC, Ye Q, Gerard RD, Schneider JW, Richardson JA, Rothermel BA, Mammen PP. Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):E129-38. Epub 2013 Dec 23. View PubMed Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM. Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):16850-5. Epub 2013 Sep 30. View PubMed Hsieh J, Schneider JW. Neural sem cells, excited. Science. 2013; 339:1534-35. View PubMed Schneider JW, Goetsch SC, Leng X, Ludwig SM, Russell JL, Yang CP, Zhang QJ. Coupling hippocampal neurogenesis to brain pH through proneurogenic small molecules that regulate proton sensing G protein-coupled receptors. ACS Chem Neurosci. 2012 Jul 18; 3(7):557-68. Epub 2012 Mar 14. View PubMed Russell JL, Goetsch SC, Aguilar HR, Frantz DE, Schneider JW. Targeting native adult heart progenitors with cardiogenic small molecules. ACS Chem Biol. 2012 Jun 15; 7(6):1067-76. Epub 2012 Apr 13. View PubMed Russell JL, Goetsch SC, Aguilar HR, Coe H, Luo X, Liu N, van Rooij E, Frantz DE, Schneider JW. Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease. ACS Chem Biol. 2012 Jun 15; 7(6):1077-83. Epub 2012 May 09. View PubMed Kato M, Han TW, Xie S, Shi K, Du X, Wu LC, Mirzaei H, Goldsmith EJ, Longgood J, Pei J, Grishin NV, Frantz DE, Schneider JW, Chen S, Li L, Sawaya MR, Eisenberg D, Tycko R, McKnight SL. Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell. 2012 May 11; 149(4):753-67. View PubMed Dioum EM, Osborne JK, Goetsch S, Russell J, Schneider JW, Cobb MH. A small molecule differentiation inducer increases insulin production by pancreatic ß cells. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20713-8. Epub 2011 Dec 05. View PubMed Zhang L, Li P, Hsu T, Aguilar HR, Frantz DE, Schneider JW, Bachoo RM, Hsieh J. Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression. Differentiation. 2011 Apr; 81(4):233-42. Epub 2011 Mar 17. View PubMed Russell JL, Goetsch SC, Gaiano NR, Hill JA, Olson EN, Schneider JW. A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circ Res. 2011 Jan 07; 108(1):51-9. Epub 2010 Nov 24. View PubMed Khakoo AY, Liu PP, Force T, Lopez-Berestein G, Jones LW, Schneider J, Hill J. Cardiotoxicity due to cancer therapy. Tex Heart Inst J. 2011; 38 (3):253-6 View PubMed Simsek T, Kocabas F, Zheng J, Deberardinis RJ, Mahmoud AI, Olson EN, Schneider JW, Zhang CC, Sadek HA. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell. 2010 Sep 03; 7(3):380-90. View PubMed Schneider JW, Gao Z, Li S, Farooqi M, Tang TS, Bezprozvanny I, Frantz DE, Hsieh J. Small-molecule activation of neuronal cell fate. Nat Chem Biol. 2008 Jul; 4(7):408-10. Epub 2008 Jun 15. View PubMed Barth AS, Kizana E, Smith RR, Terrovitis J, Dong P, Leppo MK, Zhang Y, Miake J, Olson EN, Schneider JW, Abraham MR, Marbán E. Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cells. Mol Ther. 2008 May; 16(5):957-64. Epub 2008 Mar 18. View PubMed Sadek H, Hannack B, Choe E, Wang J, Latif S, Garry MG, Garry DJ, Longgood J, Frantz DE, Olson EN, Hsieh J, Schneider JW. Cardiogenic small molecules that enhance myocardial repair by stem cells. Proc Natl Acad Sci U S A. 2008 Apr 22; 105(16):6063-8. Epub 2008 Apr 17. View PubMed Chang AY, Schneider JW. Inpatient evaluation and management of acute decompensated heart failure. Diagnostic approach; treatment options; risk factor reduction; role of specialist. J Clin Outcomes Management. 2003. Schneider JW, Chang AY, Garratt A. Trastuzumab cardiotoxicity: Speculations regarding pathophysiology and targets for further study. Semin Oncol. 2002 Jun; 29(3 Suppl 11):22-8. View PubMed Schneider JW, Chang AY, Rocco TP. Cardiotoxicity in signal transduction therapeutics: erbB2 antibodies and the heart. Semin Oncol. 2001 Oct; 28(5 Suppl 16):18-26. View PubMed Kaushal S, Schneider JW, Nadal-Ginard B, Mahdavi V. Activation of the myogenic lineage by MEF2A, a factor that induces and cooperates with MyoD. Science. 1994 Nov 18; 266(5188):1236-40. View PubMed Schneider JW, Gu W, Zhu L, Mahdavi V, Nadal-Ginard B. Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells. Science. 1994 Jun 03; 264(5164):1467-71. View PubMed Gu W, Schneider JW, Condorelli G, Kaushal S, Mahdavi V, Nadal-Ginard B. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell. 1993 Feb 12; 72(3):309-24. View PubMed Gilmore-Hebert M, Schneider JW, Greene AL, Berliner N, Stolle CA, Lomax K, Mercer RW, Benz EJ Jr. Expression of multiple Na+,K+-adenosine triphosphatase isoform genes in human hematopoietic cells. Behavior of the novel A3 isoform during induced maturation of HL60 cells. J Clin Invest. 1989 Jul; 84(1):347-51. View PubMed Yang-Feng TL, Schneider JW, Lindgren V, Shull MM, Benz EJ Jr, Lingrel JB, Francke U. Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes. Genomics. 1988 Feb; 2(2):128-38. View PubMed Schneider JW, Mercer RW, Gilmore-Hebert M, Utset MF, Lai C, Greene A, Benz EJ Jr. Tissue specificity, localization in brain, and cell-free translation of mRNA encoding the A3 isoform of Na+,K+-ATPase. Proc Natl Acad Sci U S A. 1988 Jan; 85(1):284-8. View PubMed Mercer RW, Schneider JW, Benz EJ Jr. Molecular cloning and characterization of alpha-subunit isoforms of the Na,K-ATPase. Prog Clin Biol Res. 1988; 268B:119-26. View PubMed Gilmore-Hebert M, Mercer RW, Schneider JW, Benz EJ. In vitro expression of the alpha and beta subunits of the Na,K-ATPase. Prog Clin Biol Res. 1988; 268B:71-6. View PubMed Schneider JW, Mercer RW, Benz EJ Jr, Levenson R. Molecular cloning of Na+,K+-ATPase alpha subunit gene using antibody probes. Methods Enzymol. 1988; 156:379-92 View PubMed High KA, Stolle CA, Schneider JW, Hu W, Benz EJ Jr. c-myc gene inactivation during induced maturation of HL-60 cells. Transcriptional repression and loss of a specific DNAse I hypersensitive site. J Clin Invest. 1987 Jan; 79(1):93-9. View PubMed Schneider JW, Mercer RW, Emanuel J, Levenson RM, Benz EJ Jr. Expression of genes for the alpha and beta subunits of the Na,K-ATPase in normal and drug resistant cells. Blood Cells. 1987; 13(1-2):299-307. View PubMed Mercer RW, Schneider JW, Savitz A, Emanuel J, Benz EJ Jr, Levenson R. Rat-brain Na,K-ATPase beta-chain gene: primary structure, tissue-specific expression, and amplification in ouabain-resistant HeLa C+ cells. Mol Cell Biol. 1986 Nov; 6(11):3884-90. View PubMed Emanuel JR, Garetz, Schneider, Ash, Benz, Levenson. Amplification of DNA sequences coding for the Na,K-ATPase a -subunit in ouabain-resistant C+ cells. Mol Cell Biol. 1986; 6(7):2476-81. View PubMed Schneider JW, Mercer RW, Caplan M, Emanuel JR, Sweadner KJ, Benz EJ, Levenson R. Molecular cloning of rat brain Na,K-ATPase alpha-subunit cDNA. Proc Natl Acad Sci U S A. 1985 Sep; 82(18):6357-61. View PubMed PST-20527101 الصفحة الرئيسية المنشورات