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Publications
Batton AD, Blaha CD,
Bieber A
, Lee KH, Boschen SL. Stimulation of the subparafascicular thalamic nucleus modulates dopamine release in the inferior colliculus of rats. Synapse. 2018 Oct 6; e22073 Epub 2018 Oct 06
View PubMed
Painter MM, Morrison JH, Zoecklein LJ, Rinkoski TA, Watzlawik JO, Papke LM, Warrington AE,
Bieber AJ
, Matchett WE, Turkowski KL, Poeschla EM, Rodriguez M. Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity. PLoS Pathog. 2015 Dec; 11 (12):e1005311 Epub 2015 Dec 03
View PubMed
Grahn PJ, Lee KH, Kasasbeh A, Mallory GW, Hachmann JT, Dube JR, Kimble CJ, Lobel DA,
Bieber A
, Jeong JH, Bennet KE, Lujan JL. Wireless control of intraspinal microstimulation in a rodent model of paralysis. J Neurosurg. 2015 Jul; 123 (1):232-242 Epub 2014 Dec 05
View PubMed
Paek SB, Min HK, Kim I, Knight EJ, Baek JJ,
Bieber AJ
, Lee KH, Chang SY. Frequency-dependent functional neuromodulatory effects on the motor network by ventral lateral thalamic deep brain stimulation in swine. Neuroimage. 2015 Jan 15; 105:181-8 Epub 2014 Oct 14
View PubMed
Kim I, Paek S, Nelson BD, Knight EJ, Marsh MP,
Bieber AJ
, Bennet KE, Lee KH. Implementation of a chronic unilateral intraparenchymal drug delivery system in a swine model. J Neurosci Methods. 2014 Apr 30; 227:29-34 Epub 2014 Jan 31
View PubMed
Grahn PJ, Mallory GW, Khurram OU, Berry BM, Hachmann JT,
Bieber AJ
, Bennet KE, Min HK, Chang SY, Lee KH, Lujan JL. A neurochemical closed-loop controller for deep brain stimulation: toward individualized smart neuromodulation therapies. Front Neurosci. 2014; 8:169 Epub 2014 June 25
View PubMed
Johnson HL, Hanson LM, Chen Y,
Bieber AJ
, Buono RJ, Ferraro TN, Pirko I, Johnson AJ. Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption. BMC Genomics. 2013 Oct 3; 14:678 Epub 2013 Oct 03
View PubMed
Hachmann JT, Jeong JH, Grahn PJ, Mallory GW, Evertz LQ,
Bieber AJ
, Lobel DA, Bennet KE, Lee KH, Lujan JL. Large animal model for development of functional restoration paradigms using epidural and intraspinal stimulation. PLoS One. 2013; 8 (12):e81443 Epub 2013 Dec 05
View PubMed
Kasasbeh A, Lee K,
Bieber A
, Bennet K, Chang SY. Wireless neurochemical monitoring in humans. Stereotact Funct Neurosurg. 2013; 91 (3):141-7 Epub 2013 Feb 27
View PubMed
Ta LE, Schmelzer JD,
Bieber AJ
, Loprinzi CL, Sieck GC, Brederson JD, Low PA, Windebank AJ. A novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathy. PLoS One. 2013; 8 (1):e54161 Epub 2013 Jan 10
View PubMed
Xu X, Denic A, Warrington AE,
Bieber AJ
, Rodriguez M. Therapeutics to promote CNS repair: a natural human neuron-binding IgM regulates membrane-raft dynamics and improves motility in a mouse model of multiple sclerosis. J Clin Immunol. 2013 Jan; 33 Suppl 1:S50-6 Epub 2012 Sept 19
View PubMed
Denic A, Pirko I, Wootla B,
Bieber A
, Macura S, Rodriguez M. Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis. Brain Pathol. 2012 Sep; 22 (5):698-708 Epub 2012 Mar 08
View PubMed
Xu X, Warrington AE, Wright BR,
Bieber AJ
, Van Keulen V, Pease LR, Rodriguez M. A human IgM signals axon outgrowth: coupling lipid raft to microtubules. J Neurochem. 2011 Oct; 119 (1):100-12 Epub 2011 Sept 01
View PubMed
Wootla B, Lacroix-Desmazes S, Warrington AE,
Bieber AJ
, Kaveri SV, Rodriguez M. Autoantibodies with enzymatic properties in human autoimmune diseases. J Autoimmun. 2011 Sep; 37 (2):144-50 Epub 2011 May 31
View PubMed
Denic A, Zoecklein L, Kerkvliet J, Papke L, Edukulla R, Warrington A,
Bieber A
, Pease LR, David CS, Rodriguez M. Transgenic expression of viral capsid proteins predisposes to axonal injury in a murine model of multiple sclerosis. Brain Pathol. 2011 Sep; 21 (5):501-15 Epub 2011 Feb 11
View PubMed
Podratz JL, Staff NP, Froemel D, Wallner A, Wabnig F,
Bieber AJ
, Tang A, Windebank AJ. Drosophila melanogaster: a new model to study cisplatin-induced neurotoxicity. Neurobiol Dis. 2011 Aug; 43(2):330-7. Epub 2011 Apr 15.
View PubMed
Xu X, Warrington AE,
Bieber AJ
, Rodriguez M. Enhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the network. CNS Drugs. 2011 Jul; 25 (7):555-73
View PubMed
Denic A, Johnson AJ,
Bieber AJ
, Warrington AE, Rodriguez M, Pirko I. The relevance of animal models in multiple sclerosis research. Pathophysiology. 2011 Feb; 18 (1):21-9
View PubMed
Wootla B, Denic A, Keegan BM, Winters JL, Astapenko D, Warrington AE,
Bieber AJ
, Rodriguez M. Evidence for the role of B cells and immunoglobulins in the pathogenesis of multiple sclerosis. Neurol Res Int. 2011; 2011:780712 Epub 2011 Sept 22
View PubMed
Ta LE,
Bieber AJ
, Carlton SM, Loprinzi CL, Low PA, Windebank AJ. Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice. Mol Pain. 2010 Mar 5; 6:15 Epub 2010 Mar 05
View PubMed
Bieber AJ
, Suwansrinon K, Kerkvliet J, Zhang W, Pease LR, Rodriguez M. Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair. Proc Natl Acad Sci U S A. 2010 Jan 12; 107 (2):792-7 Epub 2009 Dec 22
View PubMed
Kerkvliet J, Zoecklein L, Papke L, Denic A,
Bieber AJ
, Pease LR, David CS, Rodriguez M. Transgenic expression of the 3D polymerase inhibits Theiler's virus infection and demyelination. J Virol. 2009 Dec; 83 (23):12279-89 Epub 2009 Sept 16
View PubMed
Denic A,
Bieber A
, Warrington A, Mishra PK, Macura S, Rodriguez M. Brainstem 1H nuclear magnetic resonance (NMR) spectroscopy: marker of demyelination and repair in spinal cord. Ann Neurol. 2009 Oct; 66 (4):559-64
View PubMed
Bieber AJ
. Genetic analysis of CNS remyelination. Curr Top Microbiol Immunol. 2008; 318:177-92
View PubMed
Warrington AE,
Bieber AJ
, Ciric B, Pease LR, Van Keulen V, Rodriguez M. A recombinant human IgM promotes myelin repair after a single, very low dose. J Neurosci Res. 2007 Apr; 85 (5):967-76
View PubMed
Suznovich CT, Pu R,
Bieber AJ
. CaM kinase II isoforms are expressed at lower levels in brains of shiverer mutants. J Mol Neurosci. 2007; 31(3):297-305.
View PubMed
Bieber AJ
, Ure DR, Rodriguez M. Genetically dominant spinal cord repair in a murine model of chronic progressive multiple sclerosis. J Neuropathol Exp Neurol. 2005 Jan; 64 (1):46-57
View PubMed
Nelson AL,
Bieber AJ
, Rodriguez M. Contrasting murine models of MS. Int MS J. 2004 Dec; 11: (3)95-9.
View PubMed
Pirko I, Ciric B, Gamez J,
Bieber AJ
, Warrington AE, Johnson AJ, Hanson DP, Pease LR, Macura SI, Rodriguez M. A human antibody that promotes remyelination enters the CNS and decreases lesion load as detected by T2-weighted spinal cord MRI in a virus-induced murine model of MS. FASEB J. 2004 Oct; 18 (13):1577-9 Epub 2004 Aug 19
View PubMed
Warrington AE,
Bieber AJ
, Van Keulen V, Ciric B, Pease LR, Rodriguez M. Neuron-binding human monoclonal antibodies support central nervous system neurite extension. J Neuropathol Exp Neurol. 2004 May; 63 (5):461-73
View PubMed
Howe CL,
Bieber AJ
, Warrington AE, Pease LR, Rodriguez M. Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody. Neurobiol Dis. 2004 Feb; 15 (1):120-31
View PubMed
Ciric B, Howe CL, Paz Soldan M, Paz Soldan M, Warrington AE,
Bieber AJ
, Van Keulen V, Rodriguez M, Pease LR. Human monoclonal IgM antibody promotes CNS myelin repair independent of Fc function. Brain Pathol. 2003 Oct; 13 (4):608-16
View PubMed
Bieber AJ
, Kerr S, Rodriguez M. Efficient central nervous system remyelination requires T cells. Ann Neurol. 2003 May; 53 (5):680-4
View PubMed
Paz Soldan MM, Warrington AE,
Bieber AJ
, Ciric B, Van Keulen V, Pease LR, Rodriguez M. Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair. Mol Cell Neurosci. 2003 Jan; 22 (1):14-24
View PubMed
Mitsunaga Y, Ciric B, Van Keulen V, Warrington AE, Paz Soldan M,
Bieber AJ
, Rodriguez M, Pease LR. Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease. FASEB J. 2002 Aug; 16 (10):1325-7 Epub 2002 June 21
View PubMed
Bieber AJ
, Warrington A, Asakura K, Ciric B, Kaveri SV, Pease LR, Rodriguez M. Human antibodies accelerate the rate of remyelination following lysolecithin-induced demyelination in mice. Glia. 2002 Mar 1; 37 (3):241-9
View PubMed
Bieber AJ
, Warrington A, Warrington A, Pease LR, Rodriguez M, Rodriguez M. Humoral autoimmunity as a mediator of CNS repair. Trends Neurosci. 2001 Nov; 24 (11 Suppl):S39-44
View PubMed
Warrington AE,
Bieber AJ
, Ciric B, Van Keulen V, Pease LR, Mitsunaga Y, Paz Soldan MM, Rodriguez M, Rodriguez M. Immunoglobulin-mediated CNS repair. J Allergy Clin Immunol. 2001 Oct; 108 (4 Suppl):S121-5
View PubMed
Bieber A
, Asakura K, Warrington A, Kaveri SV, Rodriguez M. Antibody-mediated remyelination: relevance to multiple sclerosis. Mult Scler. 2000 Oct 6; (Suppl 2):S1-5, discussion S33.
Warrington AE, Asakura K,
Bieber AJ
, Ciric B, Van Keulen V, Kaveri SV, Kyle RA, Pease LR, Rodriguez M. Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis. Proc Natl Acad Sci U S A. 2000 Jun 6; 97 (12):6820-5
View PubMed
Wang YE, Chandler R, Lau P,
Bieber AJ
. Drosophila nerve cord culture: a tool for studying neural development. J Neurosci Methods. 1998 Nov 1; 85(1):21-6.
View PubMed
Hall SG,
Bieber AJ
. Mutations in the Drosophila neuroglian cell adhesion molecule affect motor neuron pathfinding and peripheral nervous system patterning. J Neurobiol. 1997 Mar; 32(3):325-40.
View PubMed
Hortsch M, Wang YM, Marikar Y,
Bieber AJ
. The cytoplasmic domain of the drosophila cell adhesion molecule neuroglian is not essential for its homophilic adhesive properties in S2 cells. J Biol Chem. 1995 Aug 11; 270(32):18809-17.
View PubMed
Clark HF, Brentrup D, Schneitz K,
Bieber A
, Goodman C, Noll M. Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila. Genes Dev. 1995 Jun 15; 9(12):1530-42.
View PubMed
Huber AH, Wang YM,
Bieber AJ
, Bjorkman PJ. Crystal structure of tandem type III fibronectin domains from drosophila neuroglian at 2.0 A. Neuron. 1994 Apr; 12(4):717-31.
View PubMed
Hortsch M, Patel NH,
Bieber AJ
, Traquina ZR, Goodman CS. Drosophila neurotactin, a surface glycoprotein with homology to serine esterases, is dynamically expressed during embryogenesis. Development. 1990 Dec; 110(4):1327-40.
View PubMed
Elkins T, Hortsch M,
Bieber AJ
, Snow PM, Goodman CS. Drosophila fasciclin I is a novel homophilic adhesion molecule that along with fasciclin III can mediate cell sorting. J Cell Biol. 1990 May; 110(5):1825-32.
View PubMed
Hortsch M,
Bieber AJ
, Patel NH, Goodman CS. Differential splicing generates a nervous system-specific form of drosophila neuroglian. Neuron. 1990 May; 4(5):697-709.
View PubMed
Snow PM,
Bieber AJ
, Goodman CS. Fasciclin III: a novel homophilic adhesion molecule in drosophila. Cell. 1989 Oct 20; 59(2):313-23.
View PubMed
Bieber AJ
, Snow PM, Hortsch M, Patel NH, Jacobs JR, Traquina ZR, Schilling J, Goodman CS. Drosophila neuroglian: a member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1. Cell. 1989; 59:447-60.
View PubMed
Mahmoud IY, Cyrus RV, Woller MJ,
Bieber A
. Development of the ovarian follicles in relation to changes in plasma parameters and 5 delta,3 beta-HSD in snapping turtle, chelydra serpentina. Comp Biochem Physiol. 1985; 82:131-6.
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