The most common causes of muscle pain are tension, stress, overuse and minor injuries. This type of pain is usually localized, affecting just one or more muscles or parts of your body. Systemic muscle pain, which you feel throughout your body, is different. It's more often the result of an infection, an illness or a side effect of a medication.

Common causes of muscle pain include:

  1. Chronic exertional compartment syndrome
  2. Chronic fatigue syndrome
  3. Claudication
  4. Delayed-onset muscle soreness (DOMS)
  5. Dermatomyositis
  6. Fibromyalgia
  7. Hypothyroidism (underactive thyroid)
  8. Influenza (flu)
  9. Lupus
  10. Lyme disease
  11. Medications, especially statins
  12. Muscle cramp
  13. Muscle strain or rupture
  14. Myofascial pain syndrome
  15. Polymyalgia rheumatica
  16. Polymyositis
  17. Porphyria
  18. Post-polio syndrome
  19. Repetitive strain injuries
  20. Rhabdomyolysis, a potentially life-threatening condition in which muscle fibers break down and enter your bloodstream — sometimes as a side effect of using statin drugs
  21. Rheumatoid arthritis
  22. Rocky Mountain spotted fever
  23. Sprains and strains
  24. Staph infections
  25. Viral infections

Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.

April 09, 2013