The most common causes of muscle pain are tension, stress, overuse and minor injuries. This type of pain is usually localized, affecting just one or more muscles or parts of your body. Systemic muscle pain, which you feel throughout your body, is different. It's more often the result of an infection, an illness or a side effect of a medication.

Common causes of muscle pain include:

  1. Chronic exertional compartment syndrome
  2. Chronic fatigue syndrome
  3. Claudication
  4. Delayed-onset muscle soreness (DOMS)
  5. Dermatomyositis
  6. Dystonia
  7. Fibromyalgia
  8. Hypothyroidism (a thyroid disorder)
  9. Influenza (flu)
  10. Lupus
  11. Lyme disease
  12. Medications, especially statins
  13. Muscle cramp: How to provide relief
  14. Muscle strain or rupture
  15. Myofascial pain syndrome
  16. Polymyalgia rheumatica
  17. Polymyositis
  18. Porphyria
  19. Post-polio syndrome
  20. Repetitive strain injuries
  21. Rhabdomyolysis, a potentially life-threatening condition in which muscle fibers break down and enter your bloodstream — sometimes as a side effect of using statin drugs
  22. Rheumatoid arthritis
  23. Rocky Mountain spotted fever
  24. Sprains and strains
  25. Staph infections
  26. Viral infections

Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.

Apr. 09, 2013