Primary sclerosing (skluh-ROHS-ing) cholangitis (koh-lan-JIE-tis) is a disease of the liver's bile ducts. These ducts transport bile to the gallbladder and intestines to aid in food digestion. In primary sclerosing cholangitis, your body attacks the bile ducts, causing them to be constantly inflamed (swollen). Over time, the inflamed bile ducts harden and develop scar tissue (cirrhosis), which disrupts bile flow, eventually causing liver damage.
Up to 30 percent of people diagnosed with primary sclerosing cholangitis will eventually develop cancer in their bile ducts.
Mayo Clinic in Rochester, Minn., ranks No. 1 for digestive disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked high performing for digestive disorders by U.S. News & World Report. Mayo Clinic also ranks among the Best Children's Hospitals for digestive disorders.
A liver transplant for primary sclerosing cholangitis brought new strength to Bruce Schwartau. "It's a joy to be able to play a full 18 holes of golf. I know what it's like to be weak, so I value my strength."